| 학회 | 한국화학공학회 |
| 학술대회 | 2008년 가을 (10/23 ~ 10/24, 부산 BEXCO) |
| 권호 | 14권 2호, p.2691 |
| 발표분야 | 생물화공 |
| 제목 | Construction of Chiral Selector Modified Surface for Recognition of Chiral Mandelic Acid by Quartz Crystal Microbalance |
| 초록 | The selective detection of individual chiral enantiomers is one of the most challenged analytical tasks. Quartz crystal microbalance (QCM) is a powerful tool for the study of chiral recognition due to its excellent mass sensitivity. The key step for selectively sensing chiral compounds on QCM is to build a chiral surface. In this study, two molecules, namely L-phenylalanine (L-Phe) and L-cysteine (L-Cys), were used as the chiral selectors to fabricate QCM chiral sensor for selective sensing L-mandelic acid (L-MA). The immobilization of these chiral selectors was fulfilled by using the self-assembled monolayers technique. The chiral recognizability of the modified surface to L-MA was investigated using a vapor diffused molecular assembly reaction method, and then determined by QCM detection and atomic force microscope (AFM) analysis. Results showed that L-Phe and L-Cys are good chiral selectors for L-MA. The high chiral recognition ability of the modified surface could be the result of the specific host-guest interactions between L-MA and the immobilized chiral selectors. |
| 저자 | Guo Hui-shi 1 , 김종민 2 , 장상목 2 , 김우식 1 |
| 소속 | 1 경희대, 2 동아대 |
| 키워드 | chiral recognition ; quartz crystal microbalance |
| VOD | VOD 보기 |
| 원문파일 | 초록 보기 |
