| 학회 | 한국화학공학회 |
| 학술대회 | 2010년 봄 (04/22 ~ 04/23, 대구 EXCO) |
| 권호 | 16권 1호, p.353 |
| 발표분야 | 생물화공 |
| 제목 | Bimetallic core-satellites single nanoprobe for the detection of Pb 2+ ion |
| 초록 | The accurate detection of metal ions is important, since they can have harmful effects on the environment and human health. In this research, bimetallic core-satellites nanoprobe was developed for the precise detection of Pb2+ ion.Core and satellite metallic nanoparticles was linked with each other by DNAzyme/substrate RNA complex which shows enzymatic activity with Pb2+ ion. In the presence of Pb2+ ions, substrate RNA can be cleavaged into two fragments by the enzymatic reaction and the satellite nanoparticles are detached from a core nanoparticle. From the structural change, the contents of Pb2+ ion can be measured by tracking a change of dielectric function of the nanoprobe.Bimetallic core-satellites nanoprobe shows a highly sensitive detection performance, because that structural change of bimetallic nanoprobe can cause a larger change of dielectric functions than that of single nanoprobe due to the interparticle plasmon coupling effect. Moreover, detection area can be reduced so far as one single nanoparticle via dark-field microscopy, scattered spectrum can give precise information according to the structural change without ensemble average. |
| 저자 | 이수승 1 , 정선일 2 , 정의근 2 , 홍수린 1 , 양영인 1 , 송현돈 1 , 최인희 3 , 강태욱 2 , 이종협 1 |
| 소속 | 1 서울대, 2 서강대, 3 Cornell Univ. |
| 키워드 | lead ; nanoprobe ; plasmonics |
| VOD | VOD 보기 |
| 원문파일 | 초록 보기 |
