| 학회 | 한국화학공학회 |
| 학술대회 | 2011년 가을 (10/26 ~ 10/28, 송도컨벤시아) |
| 권호 | 17권 2호, p.1453 |
| 발표분야 | 생물화공 |
| 제목 | Nanoscale enzyme reactors of organophosphorous hydrolase in mesoporous carbons for reliable and sensitive detection of organophosphate nerve agents |
| 초록 | It has been demonstrated that the approach of nanoscale enzyme reactors (NERs), consisting of enzyme adsorption and crosslinking, can improve both the enzyme stability and loading in mesoporous materials with a bottle-neck structure. These advantageous features of NERs result from the ship-in-a-bottle mechanism, in which crosslinked enzymes in larger-sized mesocellular pores cannot be leached out through smaller-sized bottle-neck mesopores. In the present presentation, we prepared the NERs of organophosphate hydrolase (NER-OPH) in conductive mesoporous carbons for the electrochemical detection of paraoxon. The improved performance of NER-OPH in activity, stability, sensitivity, and sensitivity stability will be presented in comparison with free and adsorbed OPH. |
| 저자 | 김재현 1 , 전철민 1 , 김창섭 2 , 차형준 2 , 김중배 1 |
| 소속 | 1 고려대, 2 포항공과대 |
| 키워드 | Biosensor ; Enzyme stabilization |
| VOD | VOD 보기 |
| 원문파일 | 초록 보기 |
