학회 한국화학공학회
학술대회 2012년 가을 (10/24 ~ 10/26, 부산 BEXCO)
권호 18권 2호, p.1736
발표분야 분리기술
제목 “Backfill” Strategy for Improving the Separation Performance in Simulated Moving Bed Chromatography
초록 Simulated moving bed (SMB) is a continuous chromatographic separation process and it has been adapted to the petrochemical, fine chemistry and pharmaceuticals. In a conventional SMB, the majority of impurity component for each product node emerged on one side in a switching period. Therefore, many operating strategies improved the separation performance of SMB by periodic modulation of certain operating parameters during a switching period such as VariCol, Partial-feed, ModiCon, and OSS SMB.  
In the previous work, our group suggested the Partial-Discard (PD) and Recycling Partial-Discard (RPD) operations from discarding and re-feeding the part of impurity in the product. As another re-feeding process, the product was re-fed to the SMB circuit in the “Backfill” operation in this work. Several methods of re-feeding were introduced and compared in the “Backfill” operation. And from the results, the guide line for “Backfill” operation design was suggested.
저자 김경민 , 이창하
소속 연세대
키워드 Simulated Moving Bed ; Backfill
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