학회 | 한국화학공학회 |
학술대회 | 2014년 가을 (10/22 ~ 10/24, 대전 DCC) |
권호 | 20권 2호, p.2479 |
발표분야 | 신진연구자 심포지엄 |
제목 | Enzyme-based biocatalysts for CO 2 sequestration |
초록 | Carbonic anhydrase (CA) is an enzyme that catalyzes reversible hydration of CO 2
. It has been recently suggested that this remarkably fast enzyme can be used for sequestration of CO 2
, making this a promising alternative for chemical CO 2
mitigation. For its practical application, we developed efficient and economic biocatalysts with high stability, mainly based on a recombinant CA originated from Neisseria gonorrhoeae (ngCA). First, we engineered ngCA in the periplasm of E. coli to promote the economical use of enzymes, thereby creating a bacterial whole-cell catalyst. Next, we developed and characterized bioinspired silica nanoparticle with recombinant ngCA autoencapsulated by the silica-condensing R5 peptide fused to the ngCA. Finally, we found and characterized thermophilic α-CAs originated from Persephonella marina and Thermovibrio ammonificans, demonstrating their remarkable thermostabilities. |
저자 | 조병훈 |
소속 | 포항공과대 |
키워드 | Carbonic Anhydrase ; Carbon Capture ; Biocatalyst |
VOD | VOD 보기 |
원문파일 | 초록 보기 |