| 학회 | 한국화학공학회 |
| 학술대회 | 2016년 가을 (10/19 ~ 10/21, 대전컨벤션센터) |
| 권호 | 22권 2호, p.2164 |
| 발표분야 | 재료 |
| 제목 | Fabricating Multi-Compartmental Hydrogel Microparticles for Biochemical Applications |
| 초록 | The multi-compartmentalized hydrogel microparticle has got interest in many research areas, possessing multi-functionality in the one single particle. Compartmentalized particles have been predominantly fabricated by microfluidic or electrohydrodynamic processes which require complex instrument. Here, we fabricated compartmentalized hydrogel microparticle by simple method with well-defined region by combining electrospinning and hydrogel photopatterning. The shapes of the hydrogel microparticles and sizes of each compartment were independently controlled by photomask shape and electrospinning time. Concept experiments were done including sequential protein release and protein binding assay. Microparticle with capacity of independently releasing two growth factors, bFGF and BMP-2 was obtained utilizing nanofibers with different degradation time. Anti-IgG and anti-IgM were bound to IgG and IgM which attached on nanofiber inside hydrogel, demonstrated by fluorescence. |
| 저자 | 조강희 , 한상원 , 민지홍 , 김민수 , 홍혜진 , 고원건 |
| 소속 | 연세대 |
| 키워드 | 화공바이오소재 |
| VOD | VOD 보기 |
| 원문파일 | 초록 보기 |
