Find Cheap Flights from Des Moines to St. Louis (DSM - STL)

Flights overview

Useful information for finding cheap flights from Des Moines to St. Louis and booking your next trip

Cheapest round-trip flights	$231	Frontier 1 stop 6 hr Mon, May 25 — Tue, Jun 2	The cheapest round-trip flight from Des Moines to St. Louis is currently $231
Cheapest one-way flight	$90	Frontier 1 stop 6 hr Wed, May 27	The cheapest one-way flight from Des Moines to St. Louis is currently $90
Last-minute weekend getaway	$419	Delta 1 stop 8 hr Thu, May 7 — Sun, May 10	The cheapest last-minute weekend getaway from Des Moines to St. Louis is currently $419
Cheapest business class flights	$470	American 1 stop 6 hr Sat, May 23 — Sat, May 30	The cheapest business class round-trip flight from Des Moines to St. Louis is currently $470

Fastest flight	3 hr 23 min	The fastest flight with stops from Des Moines to St. Louis takes 3 hr 23 min
Nonstop flights	None	There are no direct flights on this route.

When is the cheapest time to fly?

The cheapest month to fly from Des Moines to St. Louis is typically September. The most expensive month to fly is typically May.

September Cheapest	Typical prices: $110–315
May Most expensive	Typical prices: $255–400

Popular airlines from Des Moines to St. Louis

American

from $288

Typical price: $230–485

400 weekly connecting flights

DSM - STL Every day
United

from $288

Typical price: $230–520

314 weekly connecting flights

DSM - STL Every day
Delta

from $288

Typical price: $235–530

265 weekly connecting flights

DSM - STL Every day
Southwest

from $288

Typical price: $220–495

213 weekly connecting flights

DSM - STL Every day
Frontier

from $231

Typical price: $185–630

5 weekly connecting flights

DSM - STL Every Mon, Fri

Popular airports near Des Moines

Des Moines International Airport (DSM)

Des Moines United States 16 min 4 mi
Kansas City International Airport (MCI)

Kansas City United States 2 hr 57 min 168 mi
Eppley Airfield (OMA)

Omaha United States 2 hr 9 min 119 mi
Eastern Iowa Airport (CID)

Cedar Rapids United States 1 hr 52 min 100 mi

Popular airports near St. Louis

St. Louis Lambert International Airport (STL)

St. Louis United States 21 min 12 mi
General Wayne A. Downing Peoria International Airport (PIA)

Peoria United States 2 hr 36 min 143 mi
Columbia Regional Airport (COU)

Columbia United States 2 hr 8 min 109 mi
Indianapolis International Airport (IND)

Indianapolis United States 3 hr 30 min 222 mi

Frequently asked questions about flying from Des Moines to St. Louis

The cheapest flights from Des Moines to St. Louis are usually in September. Typical ticket prices in September range from $110 to $315.

The cheapest round-trip flight from Des Moines to St. Louis recently found on Google Flights was with Frontier from $231. The cheapest one-way flight was with Frontier from $90.

Some of the cheapest round-trip deals we found with different airlines:

The cheapest American flight from Des Moines to St. Louis is $288, flying from May 28 to Jun 3.
The cheapest United flight from Des Moines to St. Louis is $288, flying from May 28 to Jun 3.
The cheapest Delta flight from Des Moines to St. Louis is $288, flying from Jun 4 to Jun 10.
The cheapest Southwest flight from Des Moines to St. Louis is $288, flying from Jun 8 to Jun 16.
The cheapest Frontier flight from Des Moines to St. Louis is $231, flying from May 25 to Jun 2.

The cheapest round-trip flight from Des Moines to St. Louis starts at $231 from Mon, May 25 to Tue, Jun 2. The cheapest one-way flight starts at $90 and departs on Wed, May 27.

3 hr 23 min is the shortest flight time from Des Moines to St. Louis.

Apr–Sep is the most popular time to visit, coinciding with hot, humid summer and events like Fair St. Louis, a huge Fourth of July festival at Forest Park, and the Taste of St. Louis food festival (Sep). Weather in winter is cold, with occasional snow.

It's easy to use Google Flights to find the cheapest days to fly from Des Moines to St. Louis.
Just click the Departure label near the top of the page to open the calendar. Choose a start date and a return date to see how the round-trip fare changes on those specific days.
Adjust the trip type to see one-way fares. The cheapest available flights are highlighted and easy to spot. Once you settle on dates, click the Search button to see flight options and book the deal.

You can also turn on price tracking to get alerts if the price changes for a route or flight.

What counts as the best airline for your flights from Des Moines to St. Louis really depends on your individual needs. You may have a favorite carrier or a loyalty program you like, but price, convenience, and airports served also come into play. Flexibility and booking terms – Can you change flights if you want to stay longer or get a refund if you have to postpone your trip? – are also factors that help determine which airline is best to fly from Des Moines to St. Louis.

In terms of flights, American is the most popular. American offers 400 connecting flights per week. American flies from Des Moines International Airport (DSM) to St. Louis Lambert International Airport (STL) .

Other popular airlines flying from Des Moines to St. Louis are:

United offers 314 connecting flights per week. United flies from Des Moines International Airport (DSM) to St. Louis Lambert International Airport (STL) .
Delta offers 265 connecting flights per week. Delta flies from Des Moines International Airport (DSM) to St. Louis Lambert International Airport (STL) .
Southwest offers 213 connecting flights per week. Southwest flies from Des Moines International Airport (DSM) to St. Louis Lambert International Airport (STL) .
Frontier offers 5 connecting flights per week. Frontier flies from Des Moines International Airport (DSM) to St. Louis Lambert International Airport (STL) .

The number of connecting flights refers to distinct flights with at least one stop between Des Moines and St. Louis.

The cheapest round-trip flight from Des Moines to St. Louis recently found on Google Flights was with Frontier from $231. The cheapest one-way flight was with Frontier from $90.

Some of the cheapest round-trip deals we found with different airlines:

The cheapest American flight from Des Moines to St. Louis is $288, flying from May 28 to Jun 3.
The cheapest United flight from Des Moines to St. Louis is $288, flying from May 28 to Jun 3.
The cheapest Delta flight from Des Moines to St. Louis is $288, flying from Jun 4 to Jun 10.
The cheapest Southwest flight from Des Moines to St. Louis is $288, flying from Jun 8 to Jun 16.
The cheapest Frontier flight from Des Moines to St. Louis is $231, flying from May 25 to Jun 2.

No airline flies direct from Des Moines to St. Louis.

There are 400 American connecting flights from Des Moines to St. Louis per week. Flights are available every day.
There are 314 United connecting flights from Des Moines to St. Louis per week. Flights are available every day.
There are 265 Delta connecting flights from Des Moines to St. Louis per week. Flights are available every day.
There are 213 Southwest connecting flights from Des Moines to St. Louis per week. Flights are available every day.
There are 5 Frontier connecting flights from Des Moines to St. Louis per week. Flights are available on Monday and Friday.

Use the Stops filter while searching for flights, to see only nonstop options in your results.

The cheapest last-minute deal between Des Moines and St. Louis at price $419 is offered by Delta from Thu, May 7 to Sun, May 10.

No airline flies direct from Des Moines to St. Louis.

There are 400 American connecting flights from Des Moines to St. Louis per week. Flights are available every day.
There are 314 United connecting flights from Des Moines to St. Louis per week. Flights are available every day.
There are 265 Delta connecting flights from Des Moines to St. Louis per week. Flights are available every day.
There are 213 Southwest connecting flights from Des Moines to St. Louis per week. Flights are available every day.
There are 5 Frontier connecting flights from Des Moines to St. Louis per week. Flights are available on Monday and Friday.

Use the Stops filter while searching for flights, to see only nonstop options in your results.

There are no direct flights from Des Moines to St. Louis.

It's easy to find nonstop flights with Google Flights! Once you've searched for flights from Des Moines to St. Louis, just select the nonstop flights only option in the 'Stops’ filter in the search form and view all available direct flights and their prices.

The cheapest business class round-trip flights between Des Moines and St. Louis start at $470 from Sat, May 23 to Sat, May 30 with American.

The cheapest economy class round-trip flights between Des Moines and St. Louis start at $231 from Mon, May 25 to Tue, Jun 2.

To book business class trips from Des Moines to St. Louis, look for the default Economy selection at the top, and change it to your desired cabin class such as Premium Economy, Business Class, or First Class. You can then select your departure and arrival dates, consider available options, and book your business travel.

You can also adjust the trip type to view one-way fares.

The best last-minute getaway deal for the next weekend between Des Moines and St. Louis starts at $419 from Thu, May 7 to Sun, May 10 with Delta.

The cheapest last-minute deal between Des Moines and St. Louis at price $419 is offered by Delta from Thu, May 7 to Sun, May 10.

To find last-minute flight deals from Des Moines to St. Louis, start by entering the city names, select the desired departure and return dates, and hit the Search button to view flight options.

You can check for last-minute flights for the same day or adjust the trip type to see one-way fares.