Cheap flights from Mexico City to Panama City

Flights overview

Useful information for finding cheap flights from Mexico City to Panama City and booking your next trip
Cheapest round-trip flights $342
Avianca 1 stop 10 hr Thu, Jun 11 — Thu, Jun 18
The cheapest round-trip flight from Mexico City to Panama City is currently $342
Cheapest one-way flight $184
Avianca 1 stop 9 hr Wed, Jun 3
The cheapest one-way flight from Mexico City to Panama City is currently $184
Cheapest nonstop flights $344
COPA Nonstop 4 hr Thu, Jun 11 — Thu, Jun 18
The cheapest nonstop round-trip flight from Mexico City to Panama City is currently $344
Last-minute weekend getaway $404
Avianca 1 stop 8 hr Thu, May 7 — Mon, May 11
The cheapest last-minute weekend getaway from Mexico City to Panama City is currently $404
Cheapest business class flights $512
Aeromexico Nonstop 4 hr Thu, Jun 11 — Thu, Jun 18
The cheapest business class round-trip flight from Mexico City to Panama City is currently $512
Fastest flight 3 hr 36 min The fastest nonstop flight from Mexico City to Panama City takes 3 hr 36 min
Nonstop flights Every day There are direct flights on this route every day.

When is the cheapest time to fly?

The cheapest month to fly from Mexico City to Panama City is typically February. The most expensive month to fly is typically June.
February
Cheapest
Typical prices: $265–320
June
Most expensive
Typical prices: $320–390

Popular airlines from Mexico City to Panama City

  • COPA
    Nonstop
    from $344
    Typical price: $305–520
    42 weekly nonstop flights
    MEX - PTY Every day
  • Aeromexico
    Nonstop
    from $345
    Typical price: $310–750
    7 weekly nonstop flights
    MEX - PTY Every day
    127 weekly connecting flights
    NLU - PTY Every day
  • Avianca
    from $342
    Typical price: $305–530
    89 weekly connecting flights
    MEX - PTY Every day
  • United
    from $1,080
    Typical price: $1,050–1,750
    43 weekly connecting flights
    MEX - PTY Every day
  • American
    from $1,110
    Typical price: $1,050–1,500
    21 weekly connecting flights
    MEX - PTY Every day
  • Delta
    from $4,587
    Typical price: $4,650–5,100
    21 weekly connecting flights
    MEX - PTY Every day

Popular airports near Mexico City

  • Mexico City International Airport Benito Juárez (MEX)
    Mexico City Mexico 24 min 4 mi
  • Felipe Ángeles International Airport (NLU)
    Mexico City Mexico 1 hr 22 min 23 mi
  • Lic. Adolfo López Mateos International Airport (TLC)
    Mexico City Mexico 1 hr 7 min 29 mi
  • Queretaro International Airport (QRO)
    Santiago de Querétaro Mexico 2 hr 44 min 106 mi

Popular airports near Panama City

  • Tocumen International Airport Panama (PTY)
    Panama City Panama 28 min 11 mi
  • Panamá Pacífico International Airport (BLB)
    Balboa Panama 23 min 7 mi
  • Marcos A. Gelabert International Airport (PAC)
    Panama City Panama 14 min 2 mi
  • Rio Hato Scarlett Martinez International (RIH)
    Rio Hato Panama 1 hr 42 min 58 mi

Frequently asked questions about flying from Mexico City to Panama City

The cheapest flights from Mexico City to Panama City are usually in February. Typical ticket prices in February range from $265 to $320.
The cheapest round-trip flight from Mexico City to Panama City recently found on Google Flights was with Avianca from $342. The cheapest one-way flight was with Avianca from $184.

Some of the cheapest round-trip deals we found with different airlines:
  • The cheapest COPA flight from Mexico City to Panama City is $344, flying from Jun 11 to Jun 18.
  • The cheapest Aeromexico flight from Mexico City to Panama City is $345, flying from Jun 11 to Jun 18.
  • The cheapest Avianca flight from Mexico City to Panama City is $342, flying from Jun 11 to Jun 18.
  • The cheapest United flight from Mexico City to Panama City is $1,080, flying from Jun 5 to Jun 13.
  • The cheapest American flight from Mexico City to Panama City is $1,110, flying from Jul 16 to Jul 22.
  • The cheapest Delta flight from Mexico City to Panama City is $4,587, flying from May 7 to May 13.
The cheapest round-trip flight from Mexico City to Panama City starts at $342 from Thu, Jun 11 to Thu, Jun 18. The cheapest one-way flight starts at $184 and departs on Wed, Jun 3.
3 hr 36 min is the shortest flight time from Mexico City to Panama City.
Panama City is warm and humid year-round. Peak travel is Dec–Jan. Carnival (dates vary, Feb/Mar) is celebrated with street parties and costumed parades. During Semana Santa (dates vary, Mar/Apr), major Christian observances culminate in Easter Sunday. Rainy season is May–Nov.
It's easy to use Google Flights to find the cheapest days to fly from Mexico City to Panama City.
Just click the Departure label near the top of the page to open the calendar. Choose a start date and a return date to see how the round-trip fare changes on those specific days.
Adjust the trip type to see one-way fares. The cheapest available flights are highlighted and easy to spot. Once you settle on dates, click the Search button to see flight options and book the deal.

You can also turn on price tracking to get alerts if the price changes for a route or flight.
What counts as the best airline for your flights from Mexico City to Panama City really depends on your individual needs. You may have a favorite carrier or a loyalty program you like, but price, convenience, and airports served also come into play. Flexibility and booking terms – Can you change flights if you want to stay longer or get a refund if you have to postpone your trip? – are also factors that help determine which airline is best to fly from Mexico City to Panama City.

In terms of nonstop flights, COPA is the most popular. COPA offers 42 nonstop flights per week. COPA flies from Mexico City International Airport Benito Juárez (MEX) to Tocumen International Airport Panama (PTY) .

In terms of flights, Aeromexico is the most popular. Aeromexico offers 7 nonstop flights and 127 connecting flights per week. Aeromexico flies from Felipe Ángeles International Airport (NLU) , Mexico City International Airport Benito Juárez (MEX) to Tocumen International Airport Panama (PTY) .

Other popular airlines flying from Mexico City to Panama City are:
  • Avianca offers 89 connecting flights per week. Avianca flies from Mexico City International Airport Benito Juárez (MEX) to Tocumen International Airport Panama (PTY) .
  • United offers 43 connecting flights per week. United flies from Mexico City International Airport Benito Juárez (MEX) to Tocumen International Airport Panama (PTY) .
  • American offers 21 connecting flights per week. American flies from Mexico City International Airport Benito Juárez (MEX) to Tocumen International Airport Panama (PTY) .
  • Delta offers 21 connecting flights per week. Delta flies from Mexico City International Airport Benito Juárez (MEX) to Tocumen International Airport Panama (PTY) .
The number of connecting flights refers to distinct flights with at least one stop between Mexico City and Panama City.
The cheapest round-trip flight from Mexico City to Panama City recently found on Google Flights was with Avianca from $342. The cheapest one-way flight was with Avianca from $184.

Some of the cheapest round-trip deals we found with different airlines:
  • The cheapest COPA flight from Mexico City to Panama City is $344, flying from Jun 11 to Jun 18.
  • The cheapest Aeromexico flight from Mexico City to Panama City is $345, flying from Jun 11 to Jun 18.
  • The cheapest Avianca flight from Mexico City to Panama City is $342, flying from Jun 11 to Jun 18.
  • The cheapest United flight from Mexico City to Panama City is $1,080, flying from Jun 5 to Jun 13.
  • The cheapest American flight from Mexico City to Panama City is $1,110, flying from Jul 16 to Jul 22.
  • The cheapest Delta flight from Mexico City to Panama City is $4,587, flying from May 7 to May 13.
COPA and Aeromexico fly direct from Mexico City to Panama City.
  • There are 42 COPA direct flights from Mexico City to Panama City per week. Flights are available every day.
  • There are 7 Aeromexico direct flights from Mexico City to Panama City per week. Flights are available every day.
Use the Stops filter while searching for flights, to see only nonstop options in your results.
The cheapest last-minute deal between Mexico City and Panama City at price $404 is offered by Avianca from Thu, May 7 to Mon, May 11.
COPA and Aeromexico fly direct from Mexico City to Panama City.
  • There are 42 COPA direct flights from Mexico City to Panama City per week. Flights are available every day.
  • There are 7 Aeromexico direct flights from Mexico City to Panama City per week. Flights are available every day.
Use the Stops filter while searching for flights, to see only nonstop options in your results.
There are direct flights from Mexico City to Panama City on a daily basis.
The cheapest direct (nonstop) round-trip flights between Mexico City and Panama City start at $344 from Thu, Jun 11 to Thu, Jun 18 with COPA.
It's easy to find nonstop flights with Google Flights! Once you've searched for flights from Mexico City to Panama City, just select the nonstop flights only option in the 'Stops’ filter in the search form and view all available direct flights and their prices.
The cheapest business class round-trip flights between Mexico City and Panama City start at $512 from Thu, Jun 11 to Thu, Jun 18 with Aeromexico.
The cheapest economy class round-trip flights between Mexico City and Panama City start at $342 from Thu, Jun 11 to Thu, Jun 18.
To book business class trips from Mexico City to Panama City, look for the default Economy selection at the top, and change it to your desired cabin class such as Premium Economy, Business Class, or First Class. You can then select your departure and arrival dates, consider available options, and book your business travel.

You can also adjust the trip type to view one-way fares.
The best last-minute getaway deal for the next weekend between Mexico City and Panama City starts at $404 from Thu, May 7 to Mon, May 11 with Avianca.
The cheapest last-minute deal between Mexico City and Panama City at price $404 is offered by Avianca from Thu, May 7 to Mon, May 11.
To find last-minute flight deals from Mexico City to Panama City, start by entering the city names, select the desired departure and return dates, and hit the Search button to view flight options.

You can check for last-minute flights for the same day or adjust the trip type to see one-way fares.

Search more flights

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