Cheap flights from Mexico City to Santiago

Flights overview

Useful information for finding cheap flights from Mexico City to Santiago and booking your next trip
Cheapest round-trip flights $585
Arajet 1 stop 15 hr Thu, Jun 11 — Wed, Jun 17
The cheapest round-trip flight from Mexico City to Santiago is currently $585
Cheapest one-way flight $348
Arajet 1 stop 16 hr Sun, May 24
The cheapest one-way flight from Mexico City to Santiago is currently $348
Cheapest nonstop flights $754
LATAM Nonstop 9 hr Mon, Jun 1 — Wed, Jun 10
The cheapest nonstop round-trip flight from Mexico City to Santiago is currently $754
Last-minute weekend getaway $712
COPA 1 stop 12 hr Thu, May 7 — Sun, May 10
The cheapest last-minute weekend getaway from Mexico City to Santiago is currently $712
Cheapest business class flights $1,575
Avianca 1 stop 13 hr Thu, May 14 — Wed, May 20
The cheapest business class round-trip flight from Mexico City to Santiago is currently $1,575
Fastest flight 8 hr 50 min The fastest nonstop flight from Mexico City to Santiago takes 8 hr 50 min
Nonstop flights Some days There are direct flights on this route 6 days a week: Mon, Wed, Thu, Fri, Sat, Sun.

When is the cheapest time to fly?

The cheapest month to fly from Mexico City to Santiago is typically November. The most expensive month to fly is typically February.
November
Cheapest
Typical prices: $510–760
February
Most expensive
Typical prices: $630–870

Popular airlines from Mexico City to Santiago

  • LATAM
    Nonstop
    from $742
    Typical price: $650–1,200
    4 weekly nonstop flights
    MEX - SCL Every Mon, Tue, Wed, Fri, Sun
    72 weekly connecting flights
    MEX - SCL Every day
  • COPA
    from $712
    Typical price: $590–1,050
    153 weekly connecting flights
    MEX - SCL Every day
  • Avianca
    from $697
    Typical price: $600–1,050
    70 weekly connecting flights
    MEX - SCL Every day
  • Delta
    from $2,704
    Typical price: $2,750–3,100
    28 weekly connecting flights
    MEX - SCL Every day
  • American
    from $1,516
    Typical price: $1,750–3,050
    21 weekly connecting flights
    MEX - SCL Every day
  • Arajet
    from $585
    Typical price: $520–800
    5 weekly connecting flights
    NLU - SCL Every Mon, Wed, Thu, Sat, Sun

Popular airports near Mexico City

  • Mexico City International Airport Benito Juárez (MEX)
    Mexico City Mexico 24 min 4 mi
  • Felipe Ángeles International Airport (NLU)
    Mexico City Mexico 1 hr 22 min 23 mi
  • Lic. Adolfo López Mateos International Airport (TLC)
    Mexico City Mexico 1 hr 7 min 29 mi
  • Queretaro International Airport (QRO)
    Santiago de Querétaro Mexico 2 hr 43 min 106 mi

Popular airports near Santiago

  • Arturo Merino Benitez International Airport (SCL)
    Santiago Chile 27 min 8 mi

Frequently asked questions about flying from Mexico City to Santiago

The cheapest flights from Mexico City to Santiago are usually in November. Typical ticket prices in November range from $510 to $760.
The cheapest round-trip flight from Mexico City to Santiago recently found on Google Flights was with Arajet from $585. The cheapest one-way flight was with Arajet from $348.

Some of the cheapest round-trip deals we found with different airlines:
  • The cheapest LATAM flight from Mexico City to Santiago is $742, flying from Jun 4 to Jun 13.
  • The cheapest COPA flight from Mexico City to Santiago is $712, flying from May 7 to May 13.
  • The cheapest Avianca flight from Mexico City to Santiago is $697, flying from May 14 to May 23.
  • The cheapest Delta flight from Mexico City to Santiago is $2,704, flying from May 10 to May 16.
  • The cheapest American flight from Mexico City to Santiago is $1,516, flying from Jul 16 to Jul 23.
  • The cheapest Arajet flight from Mexico City to Santiago is $585, flying from Jun 11 to Jun 17.
The cheapest round-trip flight from Mexico City to Santiago starts at $585 from Thu, Jun 11 to Wed, Jun 17. The cheapest one-way flight starts at $348 and departs on Sun, May 24.
8 hr 50 min is the shortest flight time from Mexico City to Santiago.
Peak season is summer (Nov–Apr). Temperatures are mild year-round, but winter (May–Sep) sees frequent rain (snow in the Andes). The Santiago a Mil international theater festival takes place in Jan, as well as the Festival Nacional del Folklore, a days-long festival of traditional Chilean music and dance in the suburb of San Bernardo. The Fiesta del Vino (Apr) celebrates the fall grape harvest in the nearby wine capital of Pirque. The Fiestas Patrias (Sep) mark Chile’s freedom from Spanish rule.
It's easy to use Google Flights to find the cheapest days to fly from Mexico City to Santiago.
Just click the Departure label near the top of the page to open the calendar. Choose a start date and a return date to see how the round-trip fare changes on those specific days.
Adjust the trip type to see one-way fares. The cheapest available flights are highlighted and easy to spot. Once you settle on dates, click the Search button to see flight options and book the deal.

You can also turn on price tracking to get alerts if the price changes for a route or flight.
What counts as the best airline for your flights from Mexico City to Santiago really depends on your individual needs. You may have a favorite carrier or a loyalty program you like, but price, convenience, and airports served also come into play. Flexibility and booking terms – Can you change flights if you want to stay longer or get a refund if you have to postpone your trip? – are also factors that help determine which airline is best to fly from Mexico City to Santiago.

In terms of nonstop flights, LATAM is the most popular. LATAM offers 4 nonstop flights and 72 connecting flights per week. LATAM flies from Mexico City International Airport Benito Juárez (MEX) to Arturo Merino Benitez International Airport (SCL) .

In terms of flights, COPA is the most popular. COPA offers 153 connecting flights per week. COPA flies from Mexico City International Airport Benito Juárez (MEX) to Arturo Merino Benitez International Airport (SCL) .

Other popular airlines flying from Mexico City to Santiago are:
  • Avianca offers 70 connecting flights per week. Avianca flies from Mexico City International Airport Benito Juárez (MEX) to Arturo Merino Benitez International Airport (SCL) .
  • Delta offers 28 connecting flights per week. Delta flies from Mexico City International Airport Benito Juárez (MEX) to Arturo Merino Benitez International Airport (SCL) .
  • American offers 21 connecting flights per week. American flies from Mexico City International Airport Benito Juárez (MEX) to Arturo Merino Benitez International Airport (SCL) .
  • Arajet offers 5 connecting flights per week. Arajet flies from Felipe Ángeles International Airport (NLU) to Arturo Merino Benitez International Airport (SCL) .
The number of connecting flights refers to distinct flights with at least one stop between Mexico City and Santiago.
The cheapest round-trip flight from Mexico City to Santiago recently found on Google Flights was with Arajet from $585. The cheapest one-way flight was with Arajet from $348.

Some of the cheapest round-trip deals we found with different airlines:
  • The cheapest LATAM flight from Mexico City to Santiago is $742, flying from Jun 4 to Jun 13.
  • The cheapest COPA flight from Mexico City to Santiago is $712, flying from May 7 to May 13.
  • The cheapest Avianca flight from Mexico City to Santiago is $697, flying from May 14 to May 23.
  • The cheapest Delta flight from Mexico City to Santiago is $2,704, flying from May 10 to May 16.
  • The cheapest American flight from Mexico City to Santiago is $1,516, flying from Jul 16 to Jul 23.
  • The cheapest Arajet flight from Mexico City to Santiago is $585, flying from Jun 11 to Jun 17.
LATAM flies direct from Mexico City to Santiago.
  • There are 4 LATAM direct flights from Mexico City to Santiago per week. Flights are available on Monday, Tuesday, Wednesday, Friday and Sunday.
Use the Stops filter while searching for flights, to see only nonstop options in your results.
The cheapest last-minute deal between Mexico City and Santiago at price $712 is offered by COPA from Thu, May 7 to Sun, May 10.
LATAM flies direct from Mexico City to Santiago.
  • There are 4 LATAM direct flights from Mexico City to Santiago per week. Flights are available on Monday, Tuesday, Wednesday, Friday and Sunday.
Use the Stops filter while searching for flights, to see only nonstop options in your results.
Direct flights from Mexico City to Santiago are only available on Monday, Wednesday, Thursday, Friday, Saturday and Sunday.
The cheapest direct (nonstop) round-trip flights between Mexico City and Santiago start at $754 from Mon, Jun 1 to Wed, Jun 10 with LATAM.
It's easy to find nonstop flights with Google Flights! Once you've searched for flights from Mexico City to Santiago, just select the nonstop flights only option in the 'Stops’ filter in the search form and view all available direct flights and their prices.
The cheapest business class round-trip flights between Mexico City and Santiago start at $1,575 from Thu, May 14 to Wed, May 20 with Avianca.
The cheapest economy class round-trip flights between Mexico City and Santiago start at $585 from Thu, Jun 11 to Wed, Jun 17.
To book business class trips from Mexico City to Santiago, look for the default Economy selection at the top, and change it to your desired cabin class such as Premium Economy, Business Class, or First Class. You can then select your departure and arrival dates, consider available options, and book your business travel.

You can also adjust the trip type to view one-way fares.
The best last-minute getaway deal for the next weekend between Mexico City and Santiago starts at $712 from Thu, May 7 to Sun, May 10 with COPA.
The cheapest last-minute deal between Mexico City and Santiago at price $712 is offered by COPA from Thu, May 7 to Sun, May 10.
To find last-minute flight deals from Mexico City to Santiago, start by entering the city names, select the desired departure and return dates, and hit the Search button to view flight options.

You can check for last-minute flights for the same day or adjust the trip type to see one-way fares.

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