Cheap flights from San Francisco to Knoxville

Flights overview

Useful information for finding cheap flights from San Francisco to Knoxville and booking your next trip
Cheapest round-trip flights $250
Frontier 1 stop 19 hr Thu, Jul 23 — Wed, Jul 29
The cheapest round-trip flight from San Francisco to Knoxville is currently $250
Cheapest one-way flight $111
Frontier 1 stop 11 hr Wed, Jul 29
The cheapest one-way flight from San Francisco to Knoxville is currently $111
Last-minute weekend getaway $510
Frontier 1 stop 28 hr Thu, May 7 — Mon, May 11
The cheapest last-minute weekend getaway from San Francisco to Knoxville is currently $510
Cheapest business class flights $518
Frontier 1 stop 19 hr Thu, Jul 9 — Wed, Jul 15
The cheapest business class round-trip flight from San Francisco to Knoxville is currently $518
Fastest flight 6 hr 25 min The fastest flight with stops from San Francisco to Knoxville takes 6 hr 25 min
Nonstop flights None There are no direct flights on this route.

When is the cheapest time to fly?

The cheapest month to fly from San Francisco to Knoxville is typically September. The most expensive month to fly is typically March.
September
Cheapest
Typical prices: $270–435
March
Most expensive
Typical prices: $325–610

Popular airlines from San Francisco to Knoxville

  • United
    from $389
    Typical price: $325–670
    588 weekly connecting flights
    SFO - TYS Every day
  • American
    from $389
    Typical price: $325–620
    412 weekly connecting flights
    SFO - TYS Every day
  • Delta
    from $389
    Typical price: $360–810
    352 weekly connecting flights
    SFO - TYS Every day
  • Southwest
    from $411
    Typical price: $460–790
    34 weekly connecting flights
    SFO - TYS Every day
  • Frontier
    from $230
    Typical price: $250–680
    23 weekly connecting flights
    SFO - TYS Every day

Popular airports near San Francisco

  • San Francisco International Airport (SFO)
    San Francisco United States 19 min 11 mi
  • Oakland San Francisco Bay Airport (OAK)
    Oakland United States 27 min 11 mi
  • Sacramento International Airport (SMF)
    Sacramento United States 1 hr 34 min 78 mi
  • San Jose Mineta International Airport (SJC)
    San Jose United States 51 min 39 mi

Popular airports near Knoxville

  • McGhee Tyson Airport (TYS)
    Knoxville United States 21 min 11 mi
  • Nashville International Airport (BNA)
    Nashville United States 2 hr 38 min 154 mi
  • Hartsfield-Jackson Atlanta International Airport (ATL)
    Atlanta United States 3 hr 23 min 163 mi
  • Chattanooga Metropolitan Airport (CHA)
    Chattanooga United States 1 hr 39 min 96 mi

Frequently asked questions about flying from San Francisco to Knoxville

The cheapest flights from San Francisco to Knoxville are usually in September. Typical ticket prices in September range from $270 to $435.
The cheapest round-trip flight from San Francisco to Knoxville recently found on Google Flights was with Frontier from $250. The cheapest one-way flight was with Frontier from $111.

Some of the cheapest round-trip deals we found with different airlines:
  • The cheapest United flight from San Francisco to Knoxville is $389, flying from May 29 to Jun 4.
  • The cheapest American flight from San Francisco to Knoxville is $389, flying from May 28 to Jun 3.
  • The cheapest Delta flight from San Francisco to Knoxville is $389, flying from Jul 9 to Jul 15.
  • The cheapest Southwest flight from San Francisco to Knoxville is $411, flying from Jul 4 to Jul 11.
  • The cheapest Frontier flight from San Francisco to Knoxville is $230, flying from Jul 16 to Jul 22.
The cheapest round-trip flight from San Francisco to Knoxville starts at $250 from Thu, Jul 23 to Wed, Jul 29. The cheapest one-way flight starts at $111 and departs on Wed, Jul 29.
6 hr 25 min is the shortest flight time from San Francisco to Knoxville.
A common time to visit Knoxville is May–Oct, when the weather is warm and relatively dry. Summers (Jun–Aug) are warm to hot, and winters (Dec–Feb) are cool. Rain is possible year-round. The annual Big Ears Music Festival (Mar) features music, film and visual art. The Rhythm N' Blooms Music Festival sees performances in the city's historic district. The Dogwood Arts Festival (Apr) brings arts and crafts booths, live music and food stalls to Market Square.
It's easy to use Google Flights to find the cheapest days to fly from San Francisco to Knoxville.
Just click the Departure label near the top of the page to open the calendar. Choose a start date and a return date to see how the round-trip fare changes on those specific days.
Adjust the trip type to see one-way fares. The cheapest available flights are highlighted and easy to spot. Once you settle on dates, click the Search button to see flight options and book the deal.

You can also turn on price tracking to get alerts if the price changes for a route or flight.
What counts as the best airline for your flights from San Francisco to Knoxville really depends on your individual needs. You may have a favorite carrier or a loyalty program you like, but price, convenience, and airports served also come into play. Flexibility and booking terms – Can you change flights if you want to stay longer or get a refund if you have to postpone your trip? – are also factors that help determine which airline is best to fly from San Francisco to Knoxville.

In terms of flights, United is the most popular. United offers 588 connecting flights per week. United flies from San Francisco International Airport (SFO) to McGhee Tyson Airport (TYS) .

Other popular airlines flying from San Francisco to Knoxville are:
  • American offers 412 connecting flights per week. American flies from San Francisco International Airport (SFO) to McGhee Tyson Airport (TYS) .
  • Delta offers 352 connecting flights per week. Delta flies from San Francisco International Airport (SFO) to McGhee Tyson Airport (TYS) .
  • Southwest offers 34 connecting flights per week. Southwest flies from San Francisco International Airport (SFO) to McGhee Tyson Airport (TYS) .
  • Frontier offers 23 connecting flights per week. Frontier flies from San Francisco International Airport (SFO) to McGhee Tyson Airport (TYS) .
The number of connecting flights refers to distinct flights with at least one stop between San Francisco and Knoxville.
The cheapest round-trip flight from San Francisco to Knoxville recently found on Google Flights was with Frontier from $250. The cheapest one-way flight was with Frontier from $111.

Some of the cheapest round-trip deals we found with different airlines:
  • The cheapest United flight from San Francisco to Knoxville is $389, flying from May 29 to Jun 4.
  • The cheapest American flight from San Francisco to Knoxville is $389, flying from May 28 to Jun 3.
  • The cheapest Delta flight from San Francisco to Knoxville is $389, flying from Jul 9 to Jul 15.
  • The cheapest Southwest flight from San Francisco to Knoxville is $411, flying from Jul 4 to Jul 11.
  • The cheapest Frontier flight from San Francisco to Knoxville is $230, flying from Jul 16 to Jul 22.
No airline flies direct from San Francisco to Knoxville.
  • There are 588 United connecting flights from San Francisco to Knoxville per week. Flights are available every day.
  • There are 412 American connecting flights from San Francisco to Knoxville per week. Flights are available every day.
  • There are 352 Delta connecting flights from San Francisco to Knoxville per week. Flights are available every day.
  • There are 34 Southwest connecting flights from San Francisco to Knoxville per week. Flights are available every day.
  • There are 23 Frontier connecting flights from San Francisco to Knoxville per week. Flights are available every day.
Use the Stops filter while searching for flights, to see only nonstop options in your results.
The cheapest last-minute deal between San Francisco and Knoxville at price $510 is offered by Frontier from Thu, May 7 to Mon, May 11.
No airline flies direct from San Francisco to Knoxville.
  • There are 588 United connecting flights from San Francisco to Knoxville per week. Flights are available every day.
  • There are 412 American connecting flights from San Francisco to Knoxville per week. Flights are available every day.
  • There are 352 Delta connecting flights from San Francisco to Knoxville per week. Flights are available every day.
  • There are 34 Southwest connecting flights from San Francisco to Knoxville per week. Flights are available every day.
  • There are 23 Frontier connecting flights from San Francisco to Knoxville per week. Flights are available every day.
Use the Stops filter while searching for flights, to see only nonstop options in your results.
There are no direct flights from San Francisco to Knoxville.
It's easy to find nonstop flights with Google Flights! Once you've searched for flights from San Francisco to Knoxville, just select the nonstop flights only option in the 'Stops’ filter in the search form and view all available direct flights and their prices.
The cheapest business class round-trip flights between San Francisco and Knoxville start at $518 from Thu, Jul 9 to Wed, Jul 15 with Frontier.
The cheapest economy class round-trip flights between San Francisco and Knoxville start at $250 from Thu, Jul 23 to Wed, Jul 29.
To book business class trips from San Francisco to Knoxville, look for the default Economy selection at the top, and change it to your desired cabin class such as Premium Economy, Business Class, or First Class. You can then select your departure and arrival dates, consider available options, and book your business travel.

You can also adjust the trip type to view one-way fares.
The best last-minute getaway deal for the next weekend between San Francisco and Knoxville starts at $510 from Thu, May 7 to Mon, May 11 with Frontier.
The cheapest last-minute deal between San Francisco and Knoxville at price $510 is offered by Frontier from Thu, May 7 to Mon, May 11.
To find last-minute flight deals from San Francisco to Knoxville, start by entering the city names, select the desired departure and return dates, and hit the Search button to view flight options.

You can check for last-minute flights for the same day or adjust the trip type to see one-way fares.

Search more flights

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