Find Cheap Flights from St. Louis to Knoxville (STL - TYS)

Flights overview

Useful information for finding cheap flights from St. Louis to Knoxville and booking your next trip

Cheapest round-trip flights	$230	Frontier 1 stop 23 hr Thu, Jun 11 — Mon, Jun 15	The cheapest round-trip flight from St. Louis to Knoxville is currently $230
Cheapest one-way flight	$121	Frontier 1 stop 23 hr Sun, May 31	The cheapest one-way flight from St. Louis to Knoxville is currently $121
Last-minute weekend getaway	$575	Frontier 1 stop 23 hr Thu, May 7 — Sun, May 10	The cheapest last-minute weekend getaway from St. Louis to Knoxville is currently $575
Cheapest business class flights	$488	Frontier 1 stop 23 hr Thu, Jun 11 — Mon, Jun 15	The cheapest business class round-trip flight from St. Louis to Knoxville is currently $488

Fastest flight	2 hr 35 min	The fastest flight with stops from St. Louis to Knoxville takes 2 hr 35 min
Nonstop flights	None	There are no direct flights on this route.

When is the cheapest time to fly?

The cheapest month to fly from St. Louis to Knoxville is typically July. The most expensive month to fly is typically November.

July Cheapest	Typical prices: $225–320
November Most expensive	Typical prices: $270–540

Popular airlines from St. Louis to Knoxville

American

from $299

Typical price: $230–480

455 weekly connecting flights

STL - TYS Every day
Delta

from $311

Typical price: $250–560

282 weekly connecting flights

STL - TYS Every day
United

from $299

Typical price: $275–600

210 weekly connecting flights

STL - TYS Every day
Southwest

from $294

Typical price: $265–485

174 weekly connecting flights

STL - TYS Every day
Frontier

from $230

Typical price: $225–660

1 weekly connecting flight

STL - TYS Every Thu

Popular airports near St. Louis

St. Louis Lambert International Airport (STL)

St. Louis United States 21 min 12 mi
General Wayne A. Downing Peoria International Airport (PIA)

Peoria United States 2 hr 36 min 143 mi
Columbia Regional Airport (COU)

Columbia United States 2 hr 8 min 109 mi
Indianapolis International Airport (IND)

Indianapolis United States 3 hr 30 min 222 mi

Popular airports near Knoxville

McGhee Tyson Airport (TYS)

Knoxville United States 21 min 11 mi
Nashville International Airport (BNA)

Nashville United States 2 hr 38 min 154 mi
Hartsfield-Jackson Atlanta International Airport (ATL)

Atlanta United States 3 hr 23 min 163 mi
Chattanooga Metropolitan Airport (CHA)

Chattanooga United States 1 hr 39 min 96 mi

Frequently asked questions about flying from St. Louis to Knoxville

The cheapest flights from St. Louis to Knoxville are usually in July. Typical ticket prices in July range from $225 to $320.

The cheapest round-trip flight from St. Louis to Knoxville recently found on Google Flights was with Frontier from $230. The cheapest one-way flight was with Frontier from $121.

Some of the cheapest round-trip deals we found with different airlines:

The cheapest American flight from St. Louis to Knoxville is $299, flying from Jul 9 to Jul 12.
The cheapest Delta flight from St. Louis to Knoxville is $311, flying from Jul 9 to Jul 12.
The cheapest United flight from St. Louis to Knoxville is $299, flying from Aug 1 to Aug 3.
The cheapest Southwest flight from St. Louis to Knoxville is $294, flying from Jul 9 to Jul 12.
The cheapest Frontier flight from St. Louis to Knoxville is $230, flying from Jun 11 to Jun 15.

The cheapest round-trip flight from St. Louis to Knoxville starts at $230 from Thu, Jun 11 to Mon, Jun 15. The cheapest one-way flight starts at $121 and departs on Sun, May 31.

2 hr 35 min is the shortest flight time from St. Louis to Knoxville.

A common time to visit Knoxville is May–Oct, when the weather is warm and relatively dry. Summers (Jun–Aug) are warm to hot, and winters (Dec–Feb) are cool. Rain is possible year-round. The annual Big Ears Music Festival (Mar) features music, film and visual art. The Rhythm N' Blooms Music Festival sees performances in the city's historic district. The Dogwood Arts Festival (Apr) brings arts and crafts booths, live music and food stalls to Market Square.

It's easy to use Google Flights to find the cheapest days to fly from St. Louis to Knoxville.
Just click the Departure label near the top of the page to open the calendar. Choose a start date and a return date to see how the round-trip fare changes on those specific days.
Adjust the trip type to see one-way fares. The cheapest available flights are highlighted and easy to spot. Once you settle on dates, click the Search button to see flight options and book the deal.

You can also turn on price tracking to get alerts if the price changes for a route or flight.

What counts as the best airline for your flights from St. Louis to Knoxville really depends on your individual needs. You may have a favorite carrier or a loyalty program you like, but price, convenience, and airports served also come into play. Flexibility and booking terms – Can you change flights if you want to stay longer or get a refund if you have to postpone your trip? – are also factors that help determine which airline is best to fly from St. Louis to Knoxville.

In terms of flights, American is the most popular. American offers 455 connecting flights per week. American flies from St. Louis Lambert International Airport (STL) to McGhee Tyson Airport (TYS) .

Other popular airlines flying from St. Louis to Knoxville are:

Delta offers 282 connecting flights per week. Delta flies from St. Louis Lambert International Airport (STL) to McGhee Tyson Airport (TYS) .
United offers 210 connecting flights per week. United flies from St. Louis Lambert International Airport (STL) to McGhee Tyson Airport (TYS) .
Southwest offers 174 connecting flights per week. Southwest flies from St. Louis Lambert International Airport (STL) to McGhee Tyson Airport (TYS) .
Frontier offers 1 connecting flights per week. Frontier flies from St. Louis Lambert International Airport (STL) to McGhee Tyson Airport (TYS) .

The number of connecting flights refers to distinct flights with at least one stop between St. Louis and Knoxville.

The cheapest round-trip flight from St. Louis to Knoxville recently found on Google Flights was with Frontier from $230. The cheapest one-way flight was with Frontier from $121.

Some of the cheapest round-trip deals we found with different airlines:

The cheapest American flight from St. Louis to Knoxville is $299, flying from Jul 9 to Jul 12.
The cheapest Delta flight from St. Louis to Knoxville is $311, flying from Jul 9 to Jul 12.
The cheapest United flight from St. Louis to Knoxville is $299, flying from Aug 1 to Aug 3.
The cheapest Southwest flight from St. Louis to Knoxville is $294, flying from Jul 9 to Jul 12.
The cheapest Frontier flight from St. Louis to Knoxville is $230, flying from Jun 11 to Jun 15.

No airline flies direct from St. Louis to Knoxville.

There are 455 American connecting flights from St. Louis to Knoxville per week. Flights are available every day.
There are 282 Delta connecting flights from St. Louis to Knoxville per week. Flights are available every day.
There are 210 United connecting flights from St. Louis to Knoxville per week. Flights are available every day.
There are 174 Southwest connecting flights from St. Louis to Knoxville per week. Flights are available every day.
There are 1 Frontier connecting flights from St. Louis to Knoxville per week. Flights are available on Thursday.

Use the Stops filter while searching for flights, to see only nonstop options in your results.

The cheapest last-minute deal between St. Louis and Knoxville at price $575 is offered by Frontier from Thu, May 7 to Sun, May 10.

No airline flies direct from St. Louis to Knoxville.

There are 455 American connecting flights from St. Louis to Knoxville per week. Flights are available every day.
There are 282 Delta connecting flights from St. Louis to Knoxville per week. Flights are available every day.
There are 210 United connecting flights from St. Louis to Knoxville per week. Flights are available every day.
There are 174 Southwest connecting flights from St. Louis to Knoxville per week. Flights are available every day.
There are 1 Frontier connecting flights from St. Louis to Knoxville per week. Flights are available on Thursday.

Use the Stops filter while searching for flights, to see only nonstop options in your results.

There are no direct flights from St. Louis to Knoxville.

It's easy to find nonstop flights with Google Flights! Once you've searched for flights from St. Louis to Knoxville, just select the nonstop flights only option in the 'Stops’ filter in the search form and view all available direct flights and their prices.

The cheapest business class round-trip flights between St. Louis and Knoxville start at $488 from Thu, Jun 11 to Mon, Jun 15 with Frontier.

The cheapest economy class round-trip flights between St. Louis and Knoxville start at $230 from Thu, Jun 11 to Mon, Jun 15.

To book business class trips from St. Louis to Knoxville, look for the default Economy selection at the top, and change it to your desired cabin class such as Premium Economy, Business Class, or First Class. You can then select your departure and arrival dates, consider available options, and book your business travel.

You can also adjust the trip type to view one-way fares.

The best last-minute getaway deal for the next weekend between St. Louis and Knoxville starts at $575 from Thu, May 7 to Sun, May 10 with Frontier.

The cheapest last-minute deal between St. Louis and Knoxville at price $575 is offered by Frontier from Thu, May 7 to Sun, May 10.

To find last-minute flight deals from St. Louis to Knoxville, start by entering the city names, select the desired departure and return dates, and hit the Search button to view flight options.

You can check for last-minute flights for the same day or adjust the trip type to see one-way fares.