虚血性皮膚病
原文 Ischemic-Skin-Disease カリフォルニア大学獣医学部薬剤及び疫学科 Department of Medicine & Epidemiology, School of Veterinary Medicine, University of California, Davis, CA, USA
DOG DISEASES Does your dog have a rash, pustules or nodules as shown in these photos? If so, he may suffer from Vasculitis, an insidious blood vessel disease associated with vaccines.
ISCHEMIC SKIN DISEASE Vasculitis can result from rabies or lepto vaccine reaction, i.e. a manifest result of vaccinosis. Size and breed can affect severity and susceptibility. Vet points out a nodule typical of ischemic skin disease leading to vasculitisVessel wall inflammation or microhemorrhage may be a post-vaccination result of rabies vaccine.
なお、論文の本文中に次の記述もある。 Since this syndrome is seen predominantly in very small dogs, it is tempting to speculate that the disease may be partially linked to increased antigenic load in comparison to the body size of the dog, since the same volume of rabies vaccine is given to all dogs subcutaneously.