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Pisillo
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Palermo
Chicken special with Marinated Mushrooms truffle spread and prosciutto
Pisillo
Pisillo Italian Panini Italian Restaurant ·$$

Located in the upscale neighborhood of Manhattan, Pisillo's is a family owned Italian restaurant which opened up in 2013. The place has gained immense popularity among the locals for arguably serving the best paninis in town. They are known for using the freshly produced local ingredients and their sandwiches are huge and could last two meals. Some of their specials include roma panini, trento panini, bologna panini, venezia panini, l'Aquila panini and lots more. They also have a vegetarian menu making it a perfect place for all.

Website: pisillopanini.com

Phone: (212) 227-3104

Cross Streets: Between Fulton St and Ann St

Closing soon · 8 PM

  • Wed 11:00 AM - 8:00 PM

97 Nassau St New York, NY 10038 ·346.49 mi

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Amenities

  • Accessible
  • Wifi
  • Family friendly

Reviews

yelp
4.5 823 reviews
5 star
609 4 star
142 3 star
45 2 star
15 1 star
13
Emily P. 10/20/26

What you pay for vs. what you get, an incredible deal. I love how large the sandwiches are. The samolina bread is so good and they stuff the sandwich with the meat. I'm interested in all the other...

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Jane M. 10/08/26

Pisillo Italian Panini is known for its massive sandwiches, but unfortunately, our experience was underwhelming--both in terms of food and service. We ordered the Pisillo and the New York, but...

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Nancy A. 12/18/25

The only bad thing about this place is they ONLY accept CASH! Other than that, everything else is pretty good with their panini sandwiches that are extremely big! Today, I got a PISILLO panini...

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Jessica D. 07/12/26

Huge and filling sandwiches. Generous is an understate with the amount fillings they put. They have a few tables in and outside. Fast service. Definetly sharable.

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Czarina D. 12/06/25

Came by Pisillos since I was craving a sandwich while in NY! What a HUGE portion!!! The service was also amazing. The workers were so friendly and chatted with us to help us pick the perfect...

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