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Old time Walgreens store front
2015-01-03 12.24.21; Walgreens - 300 E Houston St -  Downtown, San Antonio TX
Old school sign
Walgeeens
Cool sign
Walgreens Drug Store ·$

Walgreens is a trusted and convenient local health destination that millions of Americans rely on every day. Our founder, Charles R. Walgreen Sr., was known for finding new ways to connect with customers on a personal level and treating each person like a guest in his own home. For over a century, we have expanded that personal connection through our network of neighborhood pharmacies and our innovative health services and products. The foundation for all of this is our trusted pharmacy expertise, and our team members who provide essential care that helps people achieve better health outcomes at an affordable cost. Pharmacy Hours: M-F 8am-11am, 11:30am-6pm

Website: walgreens.com

Phone: (210) 424-3462

Cross Streets: Near the intersection of E Houston St and Navarro St

Open now

  • Mon 7:00 AM - 10:00 PM

300 E Houston St San Antonio, TX 78205 ·1245.39 mi

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Reviews

yelp
3.5 34 reviews
5 star
10 4 star
9 3 star
6 2 star
5 1 star
4
Keith R. 01/02/26

My fiance decided to stay at a hotel near here the other night and visit some of the bars nearby. Due to bad planning on our part, we forgot the charging blocks for our phones. We decided to...

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Greg H. 03/30/25

Good location, fast service with 4 registers open. Cold inside. Cool vintage sign. Otherwise a typical Walgreens.

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Matthew U. 06/14/24

I honestly didn't need to come in here, but I found myself coming in here. I had been out walking around the city for a hot minute and found myself in need of some hydration. I figured this would...

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Ana K. 09/24/25

Today's workers were great and successfully resolved a computer issue so I could pay for my Hydrocortisone and Zyrtec and go!

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Kyla S. 01/21/24

Quick and convenient location downtown! We stopped in to get some quick snacks. The building was clean, customer service was fine. This was a quick stop, but glad to see and easy to find.

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