Yahoo
Very neat produce department!
Great Customer Service!
Spartanburg, S.C.- East Main Street Location.
Super neat and well stocked produce dept.
Beautiful Store! This Publix is my absolutely favorite grocery store! Just a Perfect place to shop!
Spartanburg, S.C.
So Many BOGO'S! There's BOGO'S on every aisle!
Information!
The most expensive chuck roast per. lb. I've ever seen around here!
Punishing Price!
Publix Pharmacy ·$$

Fill your prescriptions and shop for over-the-counter medications at Publix Pharmacy at Hillcrest Shopping Center. Our staff of knowledgeable, compassionate pharmacists provide patient counseling, immunizations, health screenings, and more. Download the Publix Pharmacy app to request and pay for refills. Visit Publix Pharmacy in Spartanburg, SC today.

Website: publix.com

Phone: (864) 253-1820

Cross Streets: Near the intersection of E Main St and Fernwood Glendale Rd

Open now

  • Sun 7:00 AM - 9:00 PM

1905 E Main St Spartanburg, SC 29307 ·249.80 mi

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Reviews

yelp
3.0 25 reviews
5 star
8 4 star
4 3 star
2 2 star
1 1 star
10
Donna M. 05/23/26

The store itself is terrific, but the pharmacy is a joke. One of the pharmacist there is a gatekeeper and thinks she knows more than my doctor. Would not recommend the Pharmacy

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Joe T. 11/24/25

Need a current sales paper? Need some fresh ideas for dinner? This information center is just about a one stop solution! While I was in here, several people were ahead of me. I was waiting for a...

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Ashley N. 09/14/25

I have been shopping at this location for years, and have been using their app to pay whenever I go through checkout. Publix was light staffed today, so I helped bag and load my cart. At one...

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Kel P. 05/08/24

What gives!!! Is there no bakery manager at this location? Can they not bake bread without almost burning it? I asked the girl if there was some that was not quite so brown. Her reply...No, it...

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Angie K. 08/07/20

There was a woman in the bakery department loading cookies onto a display tray, wearing her mask around her chin. When she saw us watching her, she touched her face and mask WITH THE SAME HANDS...

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