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Rx Chicken & Oysters Seafood Restaurant ·$$

Enjoy a wholesome meal as you dine at Rx Restaurant and Bar. This restaurant is known for serving delicious Southern delicacies prepared with fresh and locally sourced ingredients. The delectable menu, which changes daily, is followed by an extensive beverage list. Their cocktails complement the meal in the best way.

Website: rxwilmington.com

Phone: (910) 399-3080

Cross Streets: Near the intersection of Castle St and S 5th Ave

Interested in our services?

Opening soon · 5 PM

  • Tue 5:00 PM - 9:00 PM

421 Castle St Wilmington, NC 28401 ·274.51 mi

Is this your business? Verify your listing

Amenities

  • Accessible

Reviews

yelp
4.5 63 reviews
5 star
44 4 star
5 3 star
5 2 star
7 1 star
2
Tiffany G. 09/30/26

What's the one dish from your childhood you wish you could taste again? You know the one, the dish that, with one bite, could transport you back in time. Apparently, for me, it's butterbeans. Who...

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Christopher R. 07/29/26

Ridiculously over priced on this 2nd version of Rx. Terrible bartender with no personality, no talent, and miserly pours. Save your money and eat at one of the dozens of oyster houses and...

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Emily B. 07/28/26

This one has been on my list for a while. Finally made it in for brunch. Highly recommend making a reservation as they are busy! Started with a variety of oysters. Mains- one sweet, one savory....

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Rick D. 02/27/26

This place is a gem. Set inside a beautifully restored old pharmacy, the atmosphere strikes a perfect balance between historic charm and lively energy. It feels warm, welcoming, and thoughtfully...

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Desiree P. 02/15/26

This was an amazing meal with top notch service. I ended up having additional people that wanted to join my group for dinner and the staff was so accommodating. The location is not too large but...

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