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Southern Living

43 Main Dish Casserole Recipes That Practically Make Dinner For You

Mary Shannon Wells
12 min read
Caitlin Bensel; Food Stylist: Torie Cox

Caitlin Bensel; Food Stylist: Torie Cox

  • Main dish casserole recipes are a convenient and kid-friendly option for weeknight dinners.

What would dinnertime in the South be without trusty casserole recipes ? They're easy, kid-friendly, and you can usually find a spare casserole stored in the freezer for the most hectic weeknights. Although we love classic side dish casseroles for cookouts and holidays, main dish recipes are more useful for weeknight dinners. When you don't have the time to prep a main dish and several sides at dinnertime (which, who does these days?), these ideas get it all done for you.

Related: 10 5-Star Casserole Recipes We Can't Stop Making

01 of 43

Chicken Cannelloni With Roasted Red Bell Pepper Sauce

Jen Causey; Food Stylist: Jennifer Wendorf; Prop Stylist: Josh Hoggle

Jen Causey; Food Stylist: Jennifer Wendorf; Prop Stylist: Josh Hoggle

The secret to this gorgeous casserole is a quick sauce made from blending store-bought Alfredo with roasted red bell peppers. It give the dish a vibrant orange hue and lots of rich, cheesy flavor.

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02 of 43

Hamburger Rice Casserole

Morgan Hunt Glaze

Morgan Hunt Glaze

Aside from chopping an onion and a little garlic, this humble hamburger casserole requires almost no prep work. You will need a can opener at the ready for a few of the key ingredients, like fire-roasted diced tomatoes and cream of mushroom soup.

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03 of 43

Old-Fashioned Cabbage Rolls

Greg DuPree; Food Stylist: Ali Ramee; Prop Stylist: Hannah Greenwood

Greg DuPree; Food Stylist: Ali Ramee; Prop Stylist: Hannah Greenwood

We've put a Southern spin on this classic dish that is much beloved in many cultures. Our tasty twists include a tomato sauce spiked with Creole seasoning and flavored with the holy trinity, a mixture of bell pepper, onion, and celery.

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04 of 43

Baked Ziti

Greg DuPree; Food Stylist: Emily Nabors Hall; Prop Stylist: Buffy Hargett

Greg DuPree; Food Stylist: Emily Nabors Hall; Prop Stylist: Buffy Hargett

Loaded with three types of cheese (ricotta, mozzarella, and Parmesan) and a rich beef ragu, this baked pasta is the kind of stick-to-your-ribs dish that cold winter nights call for.

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05 of 43

Slow-Cooker Cowboy Casserole

Morgan Hunt Glaze; Food Stylist: Emily Nabors Hall; Prop Stylist: Christina Daley

Morgan Hunt Glaze; Food Stylist: Emily Nabors Hall; Prop Stylist: Christina Daley

This is one of those "dump and go" recipes that doesn't require much more effort than combining the ingredients in a slow cooker, setting it, and forgetting it until dinnertime.

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06 of 43

Ham And Potato Casserole

Victor Protasio, Food Stylist: Margaret Dickey

Victor Protasio, Food Stylist: Margaret Dickey

Frozen diced hash browns and cubed ham make this casserole a breeze to assemble. Better yet, it will be right at home on the table for breakfast, lunch, or dinner.

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07 of 43

Hot Chicken Salad

Caitlin Bensel; Food Stylist: Torie Cox

Caitlin Bensel; Food Stylist: Torie Cox

This old-school dish combines creamy chicken salad with pimientos, mushrooms, and water chestnuts. The mixture is topped with Cheddar, crushed potato chips, and Parmesan, and is baked until hot and bubbly.

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08 of 43

Barbecue Mac and Cheese

Hector Sanchez; Styling: Heather Chadduck Hillegas

Hector Sanchez; Styling: Heather Chadduck Hillegas

This super-Southern recipe combines two comfort food favorites—mac and cheese and barbecue. You won't believe how fast it is to make. Toppings like cornbread, barbecue sauce , and green onion really send this mac and cheese over the top.

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09 of 43

Chicken Tamale Pie

Antonis Achilleos

Antonis Achilleos

This Tex-Mex favorite has a bottom layer made with cornmeal mix that's topped with seasoned chicken, corn, and a bubbly layer of cheese.

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10 of 43

Beefy Nacho Casserole

Photographer Victor Protasio, Food Stylist Rishon Hanners, Prop Stylist Heather Chadduck

Photographer Victor Protasio, Food Stylist Rishon Hanners, Prop Stylist Heather Chadduck

Nachos are a guaranteed crowd-pleaser but they're not the most filling dinner. This casserole combines the best of both worlds for a comforting meal that you can top however you like.

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11 of 43

Sloppy Joe Casserole

Southern Living

Southern Living

Sloppy Joes are a guaranteed hit with the kids, but they're, well, sloppy. This one-dish dinner solves the messiness issue without slacking in the kid-friendly department.

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12 of 43

Zucchini Lasagna

Antonis Achilleos; Prop Styling: Kay E. Clarke; Food Styling: Tina Stamos

Antonis Achilleos; Prop Styling: Kay E. Clarke; Food Styling: Tina Stamos

Meatless Monday doesn't have to lack comfort. This summery lasagna recipe is filling and fresh. The woven zucchini makes this pretty enough to share with company.

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13 of 43

Chicken-and-Biscuit Cobbler

Alison Miksch

Alison Miksch

"Cobbler" doesn't always mean fruity and sweet—this savory, biscuit-topped casserole is one of our favorite uses of the word. This cozy dish is made all the better with homemade biscuits with chopped bacon in them.

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14 of 43

Sloppy Joe Casserole With Dinner Rolls

Photographer Victor Protasio, Food Stylist Rishon Hanners, Prop Stylist Heather Chadduck

Photographer Victor Protasio, Food Stylist Rishon Hanners, Prop Stylist Heather Chadduck

Sloppy joes get revamped into a tasty, straight-from-the-oven meal. This one-dish version is cheesy, sweet, and topped with buttery rolls. Yellow mustard and pickle relish add some zip to the filling.

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15 of 43

Creamy Chicken Alfredo Casserole

Greg DuPree; Food Stylist: Emily Nabors Hall; Prop Stylist: Buffy Hargett

Greg DuPree; Food Stylist: Emily Nabors Hall; Prop Stylist: Buffy Hargett

During the week, there's no time for slow-cooked homemade sauces and roasted chicken. That doesn't mean skimping on flavor. Store-bought sauce and rotisserie chicken speed up this incredibly comforting casserole recipe.

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16 of 43

Ham and Noodle Casserole

Caitlin Bensel; Food Stylist: Torie Cox

Caitlin Bensel; Food Stylist: Torie Cox

This is the perfect easy casserole to throw together with whatever you have on hand during busy weeks. Chive-and-onion cream cheese is the secret to the creamy sauce. This makes two 8-inch casseroles, so you can cook one now and freeze the other for later.

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17 of 43

French Onion Soup Casserole

Jennifer Causey; Prop Styling: Christine Keely; Food Styling: Torie Cox

Jennifer Causey; Prop Styling: Christine Keely; Food Styling: Torie Cox

Sweet Georgia Vidalia onions shine in this oh-so-comfy take on one of our favorite soup recipes of all time. Save time by caramelizing the onions the day before.

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18 of 43

King Ranch Chicken Casserole

Stacy K. Allen, Food Stylist: Ruth Blackburn, Prop Stylist: Christina Daley

Stacy K. Allen, Food Stylist: Ruth Blackburn, Prop Stylist: Christina Daley

King Ranch Chicken truly reigns supreme when it comes to crowd-pleasing Southern casseroles. This makes a great weeknight meal, but don't overlook it for potlucks, parties, and holidays. It's easy to double and even triple.

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19 of 43

Cheeseburger Casserole

Caitlin Bensel; Food Stylist: Torie Cox

Caitlin Bensel; Food Stylist: Torie Cox

No need to fuss with forming burger patties. This casserole puts your burger, its toppings, and your favorite side into the tastiest dish. Finish with chopped bacon and a drizzle of ketchup.

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20 of 43

Homestyle Ground Beef Casserole

This super-cozy ground beef casserole can be made up to one month in advance and kept in the freezer for your busiest nights. When you're ready to use, thaw overnight in the fridge. Garlic bread and a side salad make this a hearty meal.

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21 of 43

Ravioli Lasagna

Caitlin Bensel; Food Stylist: Torie Cox

Caitlin Bensel; Food Stylist: Torie Cox

Indulge a lasagna craving on a weeknight without all the work. Layer cheese ravioli, Italian sausage, marinara sauce, and mozzarella cheese for a skillet casserole that is ready in 30 minutes. Add a salad and bread to complete the meal.

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22 of 43

Baked Ziti with Summer Vegetables

Alison Miksch

Alison Miksch

Need to use up your fresh farmers' market haul but way more in the mood for a big plate of pasta? We've got your back. This lightened pasta is heavy on fresh taste thanks to tomatoes and squash that are in season.

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23 of 43

Kentucky Hot Brown Casserole

Victor Protasio; Food Styling: Torie Cox; Prop Styling: Kay E. Clarke

Victor Protasio; Food Styling: Torie Cox; Prop Styling: Kay E. Clarke

Kentucky's favorite sandwich gets big-batch treatment with this casserole that uses tender, slow-cooked turkey. Creamy and irresistible, your family will request this comforting meal again.

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24 of 43

Pasta-Chicken-Broccoli Bake

Iain Bagwell; Prop Stylist: Heather Chadduck; Food Stylist: Ana Kelly

Iain Bagwell; Prop Stylist: Heather Chadduck; Food Stylist: Ana Kelly

This casserole recipe has everything we love about pasta salad in a cozy, warm dish. Even nicer, the refrigerated tortellini can be baked without the extra step of pre-cooking. Broccoli, chicken, peppers, and pecans make this a truly satisfying meal.

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25 of 43

Mushroom and Thyme Chicken-Broccoli Casserole

Victor Protasio; Food Styling: Rishon Hanners; Prop Styling: Audrey Davis

Victor Protasio; Food Styling: Rishon Hanners; Prop Styling: Audrey Davis

Consider this a chicken-and-rice casserole elevated for weeknights. Mushrooms, broccoli, Fontina cheese, and thyme add a bit of elegance to ordinary chicken. Pre-cooked microwavable brown rice helps this one-skillet meal get on the table in a flash.

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26 of 43

Chicken-And-Biscuit Casserole

Jen Causey; Food Stylist: Ana Kelly; Prop Stylist: Julia Bayless

Jen Causey; Food Stylist: Ana Kelly; Prop Stylist: Julia Bayless

Creamy, comforting chicken casserole is studded with vegetables and topped with cheesy biscuits. We couldn't think of anything better on a busy weeknight.

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27 of 43

Skillet Chicken Pot Pie with Puff Pastry

Brittany Conerly; Food Stylist: Karen Rankin; Prop Stylist: Christina Brockman

Brittany Conerly; Food Stylist: Karen Rankin; Prop Stylist: Christina Brockman

This one-dish casserole has everything you crave about classic chicken pot pie in less time thanks to puff pastry. You can save even more time with a little advance prep work. You can chop the carrots and leeks as well as shred the chicken the day before and refrigerate.

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28 of 43

Creamy Kale and Pasta Bake

Hector Manuel Sanchez

Hector Manuel Sanchez

You might not believe kale could be considered comfort food, but if you try this recipe, you'll be convinced. Buy bagged kale that's pre-washed and pre-chopped to cut time. Leftovers, if you have any, make a great side dish.

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29 of 43

Spaghetti Casserole

Jennifer Davick

Jennifer Davick

You don't even have to pre-cook the noodles for this simple slow-cooker casserole recipe that makes pasta night easier than ever. With just eight ingredients, this recipe isn't complicated, and you can enjoy leftovers throughout the week.

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30 of 43

New Tuna Casserole With Potato Chips

Greg Dupree

Greg Dupree

Our updated version of Mama's classic tuna-noodle casserole is lightened up on calories but not flavor. You can make this in advance, freeze it, or eat the leftovers all week. Either way, this casserole is a winner.

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31 of 43

Chicken-Mushroom-Sage Casserole

Iain Bagwell

Iain Bagwell

There's nothing we love more than a chicken casserole, but they have a weeknight-meal reputation. This pretty recipe is company-worthy for your easiest dinner party ever.

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32 of 43

Skillet Enchiladas Suizas

Victor Protasio; Prop Styling: Christine Keely; Food Styling: Torie Cox

Victor Protasio; Prop Styling: Christine Keely; Food Styling: Torie Cox

No filling or rolling required! Our easiest enchilada recipe ever is a fun way to switch up your dinner routine.

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33 of 43

Pizza Casserole

Caitlin Bensel; Food Stylist: Torie Cox

Caitlin Bensel; Food Stylist: Torie Cox

Pizza night just got a dose of Southern comfort with this kid-friendly casserole . Add your favorite pizza toppings to this pasta bake for a fun meal that is sure to put a smile on everyone's face.

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34 of 43

Shrimp and Grits Casserole

Antonis Achilleo; Prop Styling: Christine Keely; Food Styling: Tina Bell Stamos

Antonis Achilleo; Prop Styling: Christine Keely; Food Styling: Tina Bell Stamos

This big-batch version of traditional shrimp and grits can be enjoyed from brunch to dinner. Comforting and classic, this casserole makes it easy to share with a crowd .

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35 of 43

Cheesy Ground Beef-Hash Brown Casserole

Caitlin Bensel; Food Stylist: Torie Cox

Caitlin Bensel; Food Stylist: Torie Cox

We've combined our famous ground beef casserole and hash brown casserole to make this creamy and rich dinner that's layers of goodness baked together. It's so easy to make, all you need to do is cook the ground beef, layer ingredients, and bake until golden and bubbly.

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36 of 43

Cheesy Chili Hash Brown Bake

Jennifer Davick

Jennifer Davick

Hectic week? You can still get a homemade dinner on the table with this five-ingredient recipe. Bake in ramekins for individual servings, or cook in a 13- x 9-inch baking dish.

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37 of 43

Tomato 'n' Beef Casserole With Polenta Crust

Beth Dreiling Hontzas

Beth Dreiling Hontzas

Ground beef is a foolproof staple for weeknight dinners, especially when baked into a cheesy casserole. Your family will like the familiar tomatoes and ground beef combination. The polenta base takes the dish to another level.

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38 of 43

Reunion Pea Casserole

Greg DuPree; Prop Styling: Mindi Shapiro Levine; Food Styling: Torie Cox

Greg DuPree; Prop Styling: Mindi Shapiro Levine; Food Styling: Torie Cox

Tell the family to bring their appetites: This Mama-approved casserole is filled to the brim. Sausage, cheese, and black-eyed peas will comfort the whole crowd.

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39 of 43

Italian Casserole

Jen Causey; Food Stylist: Jennifer Wendorf; Prop Stylist: Josh Hoggle

Jen Causey; Food Stylist: Jennifer Wendorf; Prop Stylist: Josh Hoggle

This recipe from our November 1990 issue has been saving us at dinnertime for decades. You can make this in two smaller dishes to bake one for now and freeze one for later.

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40 of 43

Meatloaf Casserole

Caitlin Bensel, Food Stylist: Torie Cox

Caitlin Bensel, Food Stylist: Torie Cox

This will be your new favorite meatloaf and mashed potato dinner. This fun Southern take on classic Shepherd's Pie includes a creamy mashed potato topping for a complete cozy meal in one dish.

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41 of 43

Eggplant Rollups

Greg DuPree; Prop Styling: Kay E. Clarke; Food Styling: Cat Steele

Greg DuPree; Prop Styling: Kay E. Clarke; Food Styling: Cat Steele

You won't miss the pasta in this delightfully fresh lighter take on lasagna rolls. An herbed ricotta mixture fills thinly sliced eggplant and bakes in marinara. It only takes five ingredients plus pantry basics to put this meal together.

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42 of 43

Pimiento Cheese Chicken-Broccoli Casserole

Victor Protasio; Food Styling: Rishon Hanners; Prop Styling: Audrey Davis

Victor Protasio; Food Styling: Rishon Hanners; Prop Styling: Audrey Davis

Can dinnertime get any better than a chicken and pasta casserole? With buttery crackers and pimiento cheese, your chicken casserole will never be the same. Whole-grain pasta and broccoli keep this dish balanced for healthy weeknights .

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43 of 43

Chicken-and-Wild Rice Casserole

Morgan Hunt Glaze; Food Stylist: Jennifer Wendorf; Prop Stylist: Julia Bayless

Morgan Hunt Glaze; Food Stylist: Jennifer Wendorf; Prop Stylist: Julia Bayless

If you don't have a recipe for this Southern staple, go ahead and save this one. Fast-cooking boxed long-grain and wild rice, pre-sliced almonds, and cream of mushroom soup help get this on the table in a hurry.

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Read the original article on Southern Living

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