Benzoyl Peroxide vs. Salicylic Acid: Which Is Best for Your Acne?

So, you have acne. Welcome to the club. You and 50 million other Americans have to deal with various types of acne . Thankfully, the best benzoyl peroxide products and the best salicylic acid products can absorb excess oil, unclog pores, and prevent future breakouts.

Both acne-fighting ingredients are easily accessible (you can even find them at the drugstore), available in various concentrations, and come in cleanser, spot treatment , and pimple sticker delivery methods. Despite their similarities, the ingredients work slightly differently (benzoyl peroxide targets bacteria and inflammation, while salicylic acid focuses on exfoliation and pore cleanout). Knowing which is best suited to handle your current skin concern is quite literally the key to a clearer complexion.

To help you settle the benzoyl peroxide vs salicylic acid debate once and for all, we tapped board-certified dermatologists Marisa Garshick , M.D. FAAD, Christine Choi Kim , M.D. FAAD, and Pooja Rambhia , M.D. FAAD. Here, they're sharing insight into the pros and cons of both ingredients, offering advice on how to incorporate them into your skincare routine for acne , and providing a realistic timeline for when to expect to see results.

Benzoyl Peroxide vs Salicylic Acid: What's the Difference?

"The biggest difference between the two ingredients is that benzoyl peroxide has antibacterial properties and is more helpful for inflammatory acne lesions like tender red papules and pustules," explains Dr. Kim. "However, salicylic acid has stronger comedolytic effects, so it's more effective at treating and preventing blackheads and whiteheads."

The Benefits of Benzoyl Peroxide and Salicylic Acid

The main similarity between benzoyl peroxide and salicylic acid is their ability to fight acne. "Individuals who struggle with acne can benefit from adding either ingredient to their skincare routine," says Dr. Garshick. "Both aid in preventing clogged pores by shedding dead skin cells and excess sebum," notes Dr. Rambhia. Still, their individualized benefits are nuanced, and each is best suited for different types of acne.

• Benzoyl Peroxide

Most commonly found in face washes for acne , benzoyl peroxide gets a dermatologist stamp of approval for its "ability to kill acne-causing bacteria, reduce inflammation, and prevent the formation of new pimples," says Dr. Garshick. While it's effective on comedonal acne, such as blackheads and whiteheads, it's best known for fighting inflammatory acne, like cysts and pustules that tend to be red, swollen, and painful.

• Salicylic Acid

While benzoyl peroxide is a keratolytic agent (aka an exfoliator that cleans out pores), salicylic acid is a stronger one—by a long shot. "It works by exfoliating the skin, shedding dead skin cells, and clearing up clogged pores," notes Dr. Rambhia. It's ideal for blackheads and whiteheads. "It also tends to be less irritating when compared to benzoyl peroxide, making it a safer choice for those with sensitive skin when used correctly."

The Side Effects of Salicylic Acid and Benzoyl Peroxide

You don't have to worry about any serious side effects with either ingredient. The American Academy of Dermatology recommends both. Plus, they are pregnancy-safe and are overwhelmingly well-tolerated.

• Benzoyl Peroxide Side Effects

While benzoyl peroxide is generally safe to use, it can cause side effects like dryness, redness, and peeling, particularly when first introduced to the skin. "Those with other dermatologic conditions involving the area of concern, such as rosacea or eczema, may also experience irritation from benzoyl peroxide," says Dr. Rambhia.

The ingredient also tends to leave its mark. "Benzoyl peroxide can also bleach dark clothing, bedding, and even your hair," adds Dr. Kim. If you are going to use it before bed, consider laying a towel down or using a pillowcase you don't care about.

• Salicylic Acid Side Effects

Salicylic acid is more well tolerated than benzoyl peroxide, but it can still cause a bit of discomfort. "There can be dryness, irritation, redness, and stinging, especially in individuals with sensitive skin or when used in high concentrations," says Dr. Garshick.

How to Know if Salicylic Acid or Benzoyl Peroxide Is Right for You

• Type of Acne

"Those with inflammatory acne may find benzoyl peroxide particularly effective due to its antibacterial properties," says Dr. Garshick, noting that inflammatory acne includes cysts and pustules. "Individuals with comedonal acne, such as blackheads and whiteheads, may benefit more from salicylic acid's ability to penetrate and clear clogged pores."

• Skin Type

Salicylic acid may be the more tolerable option for sensitive skin. That said, benzoyl peroxide isn't out of the question. You may want to consider a short contact treatment, such as a face wash. Those with oily skin may also prefer salicylic acid, as it can regulate long-term sebum production.

• Lifestyle

Because benzoyl peroxide tends to stain bedding or clothing, it might not be the best choice if you want to preserve your sheets. Pimple patches, which are great for on-the-go treatments, also typically feature salicylic acid as the active ingredient.

The Best Benzoyl Peroxide Products

The Inky List Supersolutions 5% Benzoyl Peroxide Cleanser Acne Solution

My go-to benzoyl peroxide cleanser hack: leave the product on your face for 10 minutes and it'll double as a face mask. This particular option is affordable and last forever, so I never feel guilty using a bit extra.

Kate Somerville Anti Bac Acne Clearing Lotion

While most benozyl peroxide product come in face wash or spot treatment formulations, this one is a lotion. It gives skin the hydration it craves, while simultaneously balancing oil production in the longterm.

Panoxyl Antimicrobial Hydrating Acne Creamy Wash

A classic that is recommended by every dermatologist I spoke to, PanOxyl's face wash is gentle enough for daily use, and still manages to prevent new breakouts from forming.

CeraVe Acne Foaming Cream Cleanser

A dermatologist-loved product, this foaming cleanser contains four percent benzoyl peroxide. You should experience any irritation at this concentration–and will be left with that squeaky clean feel.

La Roche-Posay Effaclar Duo Dual Acne Treatment With Benzoyl Peroxide

My personal favorite spot treatment, La Roche-Posay's Effaclar Duo has been responsible for getting rid of many of my pimples overnight. I use a Q-tip to apply it directly to a blemish, but you can apply it over a greater area of skin, too.

Bubble Fade Away Benzoyl Peroxide Acne Spot Treatment

Bubble is a teen-friendly brand, but don't let the cutesy packaging deter you. This highly efficacious spot treatment contains five percent benozyl peroxide to treat breakouts—and licorice root to brighten acne scars.

The Best Salicylic Acid Products

Paula's Choice Skin Perfecting 2% Bha Liquid Exfoliant for Clear Skin

Whenever anyone asks me for a recommendation to treat large pores or blackheads, I instantly put them onto Paula's Choice. A swipe of this a day truly keeps the clogged comedones at bay. (Sorry for the pun, I had to.)

Murad Rapid Relief Acne Spot Treatment

When I was in the height of my teen acne stage, this product never left my side. To this day, it's my go-to product when whiteheads creep up on my forehead. It acts fast and doesn't irritate even my incredibly sensitive skin.

Glow Recipe Strawberry Smooth Bha + Aha Salicylic Acid Serum

While acne products have a habit of being dubbed unsexy skincare , I'd argue this pretty pink bottle is, in fact, very sexy. And, it works. Salicylic acid teams up with AHAs like lactic and glycolic acid to create a creamy (deliciously smelling) serum that targets blackheads and whiteheads.

The Ordinary Salicylic Acid 2% Masque

If your breakouts are mild and sporadic, you might not need a daily treatment. Enter: The Ordinary's face mask. Use it once a week to keep breakouts under control.

Caudalie Vinopure Natural Salicylic Acid Pore Minimizing Serum

Uneven texture and large pores will fade over time when you regularly use this serum. It doesn't contain a full two percent salicylic acid, so it shouldn't be your primary acne treatment. However, it's a great supplemental serum for acne maintenance.

Necessaire The Body Acne Wash

It's important to have a body skincare routine . If you frequently get back or chest acne , incorporating a salicylic body wash into your shower routine. It's the best course of action and will ensure you're deeply cleansing all oil, dirt, and grease out off your skin.

How to Incorporate Benzoyl Peroxide and Salicylic Acid Into Your Skincare Routine

How you add benzoyl peroxide or salicylic acid into your skincare is largely up to your tolerance and preference. "Benzoyl peroxide can be used in the morning or at night, as can salicylic acid." says Dr. Garshick. That said, you'll only want to use either ingredient once per day, and follow them up with a deeply hydrating moisturizer to prevent (or minimize) irritation, peeling, and flaking, as well as an SPF. "Both benzoyl peroxide and salicylic acid can make you more sensitive to the sun, so whenever incorporating these ingredients, it is important to remember sunscreen," she adds.

If you have retinol in your routine, Dr. Rambhia recommends using benzoyl peroxide or salicylic acid exclusively in the morning.

Can I Use Benzoyl Peroxide and Salicylic Acid Together?

It depends. Some people with oily, thicker skin might be able to tolerate using one ingredient in the morning and one at night. But by and large double dipping in these acne-fighting ingredients will lead to "excessive dryness and irritation," explains Dr. Garshick.

What Concentration of Benzoyl Peroxide and Salicylic Acid Is Best?

• Benzoyl Peroxide Concentration

"In studies , benzoyl peroxide is equally effective at concentrations of 2.5 percent, five percent, and ten percent, but its irritation profile increases with higher concentrations," says Dr. Kim. That in mind, it's often recommended to start with five percent for your face. A 10 percent concentration should be well tolerated if you're treating body acne .

• Salicylic Acid Concentration

Salicylic acid comes in concentrations ranging from 0.5 percent to two percent for over-the-counter topical use. "For those with mild to moderate acne, including blackheads and whiteheads, two percent tends to provide more effective exfoliation and unclogging of pores," says Dr. Rambhia.

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