Cheap flights from Knoxville to San Diego

Flights overview

Useful information for finding cheap flights from Knoxville to San Diego and booking your next trip
Cheapest round-trip flights $210
Frontier 1 stop 20 hr Mon, Jun 8 — Wed, Jun 17
The cheapest round-trip flight from Knoxville to San Diego is currently $210
Cheapest one-way flight $111
Frontier 1 stop 16 hr Wed, Jul 29
The cheapest one-way flight from Knoxville to San Diego is currently $111
Last-minute weekend getaway $407
American 1 stop 8 hr Sat, May 9 — Mon, May 11
The cheapest last-minute weekend getaway from Knoxville to San Diego is currently $407
Cheapest business class flights $569
Frontier 1 stop 16 hr Mon, May 25 — Mon, Jun 1
The cheapest business class round-trip flight from Knoxville to San Diego is currently $569
Fastest flight 5 hr 40 min The fastest flight with stops from Knoxville to San Diego takes 5 hr 40 min
Nonstop flights None There are no direct flights on this route.

When is the cheapest time to fly?

The cheapest month to fly from Knoxville to San Diego is typically January. The most expensive month to fly is typically March.
January
Cheapest
Typical prices: $245–470
March
Most expensive
Typical prices: $330–580

Popular airlines from Knoxville to San Diego

  • American
    from $337
    Typical price: $310–580
    460 weekly connecting flights
    TYS - SAN Every day
  • Delta
    from $337
    Typical price: $350–750
    369 weekly connecting flights
    TYS - SAN Every day
  • Southwest
    from $389
    Typical price: $395–690
    289 weekly connecting flights
    TYS - SAN Every day
  • United
    from $384
    Typical price: $320–610
    247 weekly connecting flights
    TYS - SAN Every day
  • Frontier
    from $210
    Typical price: $235–570
    7 weekly connecting flights
    TYS - SAN Every Fri, Sun

Popular airports near Knoxville

  • McGhee Tyson Airport (TYS)
    Knoxville United States 21 min 11 mi
  • Nashville International Airport (BNA)
    Nashville United States 2 hr 38 min 154 mi
  • Hartsfield-Jackson Atlanta International Airport (ATL)
    Atlanta United States 3 hr 23 min 163 mi
  • Chattanooga Metropolitan Airport (CHA)
    Chattanooga United States 1 hr 39 min 96 mi

Popular airports near San Diego

  • San Diego International Airport (SAN)
    San Diego United States 10 min 2 mi
  • Tijuana International Airport (TIJ)
    Tijuana Mexico 37 min 16 mi
  • Los Angeles International Airport (LAX)
    Los Angeles United States 2 hr 2 min 111 mi
  • John Wayne Airport (SNA)
    Santa Ana United States 1 hr 21 min 78 mi

Frequently asked questions about flying from Knoxville to San Diego

The cheapest flights from Knoxville to San Diego are usually in January. Typical ticket prices in January range from $245 to $470.
The cheapest round-trip flight from Knoxville to San Diego recently found on Google Flights was with Frontier from $210. The cheapest one-way flight was with Frontier from $111.

Some of the cheapest round-trip deals we found with different airlines:
  • The cheapest American flight from Knoxville to San Diego is $337, flying from May 28 to Jun 6.
  • The cheapest Delta flight from Knoxville to San Diego is $337, flying from Jul 4 to Jul 11.
  • The cheapest Southwest flight from Knoxville to San Diego is $389, flying from Aug 1 to Aug 8.
  • The cheapest United flight from Knoxville to San Diego is $384, flying from Jul 4 to Jul 11.
  • The cheapest Frontier flight from Knoxville to San Diego is $210, flying from Jun 8 to Jun 17.
The cheapest round-trip flight from Knoxville to San Diego starts at $210 from Mon, Jun 8 to Wed, Jun 17. The cheapest one-way flight starts at $111 and departs on Wed, Jul 29.
5 hr 40 min is the shortest flight time from Knoxville to San Diego.
Jun–Aug is when most people visit San Diego, where the weather's temperate year-round. Beaches are less crowded Dec–Feb, which bring cooler temperatures but brighter sun. Whale-watching season is from mid-Dec–mid-Mar. Major annual events include Comic-Con International (Jul), a massive comic book convention with workshops and film screenings. Fleet Week (autumn) is a large military appreciation event featuring Navy ship tours, an air show and more.
It's easy to use Google Flights to find the cheapest days to fly from Knoxville to San Diego.
Just click the Departure label near the top of the page to open the calendar. Choose a start date and a return date to see how the round-trip fare changes on those specific days.
Adjust the trip type to see one-way fares. The cheapest available flights are highlighted and easy to spot. Once you settle on dates, click the Search button to see flight options and book the deal.

You can also turn on price tracking to get alerts if the price changes for a route or flight.
What counts as the best airline for your flights from Knoxville to San Diego really depends on your individual needs. You may have a favorite carrier or a loyalty program you like, but price, convenience, and airports served also come into play. Flexibility and booking terms – Can you change flights if you want to stay longer or get a refund if you have to postpone your trip? – are also factors that help determine which airline is best to fly from Knoxville to San Diego.

In terms of flights, American is the most popular. American offers 460 connecting flights per week. American flies from McGhee Tyson Airport (TYS) to San Diego International Airport (SAN) .

Other popular airlines flying from Knoxville to San Diego are:
  • Delta offers 369 connecting flights per week. Delta flies from McGhee Tyson Airport (TYS) to San Diego International Airport (SAN) .
  • Southwest offers 289 connecting flights per week. Southwest flies from McGhee Tyson Airport (TYS) to San Diego International Airport (SAN) .
  • United offers 247 connecting flights per week. United flies from McGhee Tyson Airport (TYS) to San Diego International Airport (SAN) .
  • Frontier offers 7 connecting flights per week. Frontier flies from McGhee Tyson Airport (TYS) to San Diego International Airport (SAN) .
The number of connecting flights refers to distinct flights with at least one stop between Knoxville and San Diego.
The cheapest round-trip flight from Knoxville to San Diego recently found on Google Flights was with Frontier from $210. The cheapest one-way flight was with Frontier from $111.

Some of the cheapest round-trip deals we found with different airlines:
  • The cheapest American flight from Knoxville to San Diego is $337, flying from May 28 to Jun 6.
  • The cheapest Delta flight from Knoxville to San Diego is $337, flying from Jul 4 to Jul 11.
  • The cheapest Southwest flight from Knoxville to San Diego is $389, flying from Aug 1 to Aug 8.
  • The cheapest United flight from Knoxville to San Diego is $384, flying from Jul 4 to Jul 11.
  • The cheapest Frontier flight from Knoxville to San Diego is $210, flying from Jun 8 to Jun 17.
No airline flies direct from Knoxville to San Diego.
  • There are 460 American connecting flights from Knoxville to San Diego per week. Flights are available every day.
  • There are 369 Delta connecting flights from Knoxville to San Diego per week. Flights are available every day.
  • There are 289 Southwest connecting flights from Knoxville to San Diego per week. Flights are available every day.
  • There are 247 United connecting flights from Knoxville to San Diego per week. Flights are available every day.
  • There are 7 Frontier connecting flights from Knoxville to San Diego per week. Flights are available on Friday and Sunday.
Use the Stops filter while searching for flights, to see only nonstop options in your results.
The cheapest last-minute deal between Knoxville and San Diego at price $407 is offered by American from Sat, May 9 to Mon, May 11.
No airline flies direct from Knoxville to San Diego.
  • There are 460 American connecting flights from Knoxville to San Diego per week. Flights are available every day.
  • There are 369 Delta connecting flights from Knoxville to San Diego per week. Flights are available every day.
  • There are 289 Southwest connecting flights from Knoxville to San Diego per week. Flights are available every day.
  • There are 247 United connecting flights from Knoxville to San Diego per week. Flights are available every day.
  • There are 7 Frontier connecting flights from Knoxville to San Diego per week. Flights are available on Friday and Sunday.
Use the Stops filter while searching for flights, to see only nonstop options in your results.
There are no direct flights from Knoxville to San Diego.
It's easy to find nonstop flights with Google Flights! Once you've searched for flights from Knoxville to San Diego, just select the nonstop flights only option in the 'Stops’ filter in the search form and view all available direct flights and their prices.
The cheapest business class round-trip flights between Knoxville and San Diego start at $569 from Mon, May 25 to Mon, Jun 1 with Frontier.
The cheapest economy class round-trip flights between Knoxville and San Diego start at $210 from Mon, Jun 8 to Wed, Jun 17.
To book business class trips from Knoxville to San Diego, look for the default Economy selection at the top, and change it to your desired cabin class such as Premium Economy, Business Class, or First Class. You can then select your departure and arrival dates, consider available options, and book your business travel.

You can also adjust the trip type to view one-way fares.
The best last-minute getaway deal for the next weekend between Knoxville and San Diego starts at $407 from Sat, May 9 to Mon, May 11 with American.
The cheapest last-minute deal between Knoxville and San Diego at price $407 is offered by American from Sat, May 9 to Mon, May 11.
To find last-minute flight deals from Knoxville to San Diego, start by entering the city names, select the desired departure and return dates, and hit the Search button to view flight options.

You can check for last-minute flights for the same day or adjust the trip type to see one-way fares.

Search more flights

Popular trips from Knoxville

  1. Paris
    $879
    Oct 24 — Nov 2
    2 stops 16 hr 25 min Delta, Scandinavian Airlines
  2. Denver
    $325
    Aug 13 — Aug 19
    Nonstop 3 hr 15 min Southwest
  3. Seattle
    $508
    Jun 4 — Jun 11
    1 stop 8 hr 34 min Delta
  4. Miami
    $86
    May 14 — May 23
    Nonstop 1 hr 59 min Allegiant

Find cheap flights from Knoxville to anywhere

Find cheap flights on popular routes