Cheap flights from San Diego to Knoxville

Flights overview

Useful information for finding cheap flights from San Diego to Knoxville and booking your next trip
Cheapest round-trip flights $230
Frontier 1 stop 11 hr Mon, Jun 1 — Mon, Jun 8
The cheapest round-trip flight from San Diego to Knoxville is currently $230
Cheapest one-way flight $105
Frontier 1 stop 7 hr Wed, Jul 29
The cheapest one-way flight from San Diego to Knoxville is currently $105
Last-minute weekend getaway $613
Frontier 1 stop 7 hr Fri, May 8 — Sun, May 10
The cheapest last-minute weekend getaway from San Diego to Knoxville is currently $613
Cheapest business class flights $535
Frontier 1 stop 11 hr Mon, Jun 1 — Mon, Jun 8
The cheapest business class round-trip flight from San Diego to Knoxville is currently $535
Fastest flight 5 hr 40 min The fastest flight with stops from San Diego to Knoxville takes 5 hr 40 min
Nonstop flights None There are no direct flights on this route.

When is the cheapest time to fly?

The cheapest month to fly from San Diego to Knoxville is typically January. The most expensive month to fly is typically March.
January
Cheapest
Typical prices: $255–460
March
Most expensive
Typical prices: $315–560

Popular airlines from San Diego to Knoxville

  • American
    from $337
    Typical price: $310–590
    429 weekly connecting flights
    SAN - TYS Every day
  • Delta
    from $337
    Typical price: $350–760
    393 weekly connecting flights
    SAN - TYS Every day
  • United
    from $337
    Typical price: $315–620
    221 weekly connecting flights
    SAN - TYS Every day
  • Southwest
    from $394
    Typical price: $400–720
    175 weekly connecting flights
    SAN - TYS Every day
  • Frontier
    from $230
    Typical price: $240–610
    12 weekly connecting flights
    SAN - TYS Every Tue, Wed, Thu, Fri, Sun

Popular airports near San Diego

  • San Diego International Airport (SAN)
    San Diego United States 10 min 2 mi
  • Tijuana International Airport (TIJ)
    Tijuana Mexico 37 min 16 mi
  • Los Angeles International Airport (LAX)
    Los Angeles United States 2 hr 2 min 111 mi
  • John Wayne Airport (SNA)
    Santa Ana United States 1 hr 21 min 78 mi

Popular airports near Knoxville

  • McGhee Tyson Airport (TYS)
    Knoxville United States 21 min 11 mi
  • Nashville International Airport (BNA)
    Nashville United States 2 hr 38 min 154 mi
  • Hartsfield-Jackson Atlanta International Airport (ATL)
    Atlanta United States 3 hr 23 min 163 mi
  • Chattanooga Metropolitan Airport (CHA)
    Chattanooga United States 1 hr 39 min 96 mi

Frequently asked questions about flying from San Diego to Knoxville

The cheapest flights from San Diego to Knoxville are usually in January. Typical ticket prices in January range from $255 to $460.
The cheapest round-trip flight from San Diego to Knoxville recently found on Google Flights was with Frontier from $230. The cheapest one-way flight was with Frontier from $105.

Some of the cheapest round-trip deals we found with different airlines:
  • The cheapest American flight from San Diego to Knoxville is $337, flying from May 29 to Jun 6.
  • The cheapest Delta flight from San Diego to Knoxville is $337, flying from May 28 to Jun 3.
  • The cheapest United flight from San Diego to Knoxville is $337, flying from May 28 to Jun 3.
  • The cheapest Southwest flight from San Diego to Knoxville is $394, flying from Jul 25 to Aug 1.
  • The cheapest Frontier flight from San Diego to Knoxville is $230, flying from Jun 1 to Jun 8.
The cheapest round-trip flight from San Diego to Knoxville starts at $230 from Mon, Jun 1 to Mon, Jun 8. The cheapest one-way flight starts at $105 and departs on Wed, Jul 29.
5 hr 40 min is the shortest flight time from San Diego to Knoxville.
A common time to visit Knoxville is May–Oct, when the weather is warm and relatively dry. Summers (Jun–Aug) are warm to hot, and winters (Dec–Feb) are cool. Rain is possible year-round. The annual Big Ears Music Festival (Mar) features music, film and visual art. The Rhythm N' Blooms Music Festival sees performances in the city's historic district. The Dogwood Arts Festival (Apr) brings arts and crafts booths, live music and food stalls to Market Square.
It's easy to use Google Flights to find the cheapest days to fly from San Diego to Knoxville.
Just click the Departure label near the top of the page to open the calendar. Choose a start date and a return date to see how the round-trip fare changes on those specific days.
Adjust the trip type to see one-way fares. The cheapest available flights are highlighted and easy to spot. Once you settle on dates, click the Search button to see flight options and book the deal.

You can also turn on price tracking to get alerts if the price changes for a route or flight.
What counts as the best airline for your flights from San Diego to Knoxville really depends on your individual needs. You may have a favorite carrier or a loyalty program you like, but price, convenience, and airports served also come into play. Flexibility and booking terms – Can you change flights if you want to stay longer or get a refund if you have to postpone your trip? – are also factors that help determine which airline is best to fly from San Diego to Knoxville.

In terms of flights, American is the most popular. American offers 429 connecting flights per week. American flies from San Diego International Airport (SAN) to McGhee Tyson Airport (TYS) .

Other popular airlines flying from San Diego to Knoxville are:
  • Delta offers 393 connecting flights per week. Delta flies from San Diego International Airport (SAN) to McGhee Tyson Airport (TYS) .
  • United offers 221 connecting flights per week. United flies from San Diego International Airport (SAN) to McGhee Tyson Airport (TYS) .
  • Southwest offers 175 connecting flights per week. Southwest flies from San Diego International Airport (SAN) to McGhee Tyson Airport (TYS) .
  • Frontier offers 12 connecting flights per week. Frontier flies from San Diego International Airport (SAN) to McGhee Tyson Airport (TYS) .
The number of connecting flights refers to distinct flights with at least one stop between San Diego and Knoxville.
The cheapest round-trip flight from San Diego to Knoxville recently found on Google Flights was with Frontier from $230. The cheapest one-way flight was with Frontier from $105.

Some of the cheapest round-trip deals we found with different airlines:
  • The cheapest American flight from San Diego to Knoxville is $337, flying from May 29 to Jun 6.
  • The cheapest Delta flight from San Diego to Knoxville is $337, flying from May 28 to Jun 3.
  • The cheapest United flight from San Diego to Knoxville is $337, flying from May 28 to Jun 3.
  • The cheapest Southwest flight from San Diego to Knoxville is $394, flying from Jul 25 to Aug 1.
  • The cheapest Frontier flight from San Diego to Knoxville is $230, flying from Jun 1 to Jun 8.
No airline flies direct from San Diego to Knoxville.
  • There are 429 American connecting flights from San Diego to Knoxville per week. Flights are available every day.
  • There are 393 Delta connecting flights from San Diego to Knoxville per week. Flights are available every day.
  • There are 221 United connecting flights from San Diego to Knoxville per week. Flights are available every day.
  • There are 175 Southwest connecting flights from San Diego to Knoxville per week. Flights are available every day.
  • There are 12 Frontier connecting flights from San Diego to Knoxville per week. Flights are available on Tuesday, Wednesday, Thursday, Friday and Sunday.
Use the Stops filter while searching for flights, to see only nonstop options in your results.
The cheapest last-minute deal between San Diego and Knoxville at price $613 is offered by Frontier from Fri, May 8 to Sun, May 10.
No airline flies direct from San Diego to Knoxville.
  • There are 429 American connecting flights from San Diego to Knoxville per week. Flights are available every day.
  • There are 393 Delta connecting flights from San Diego to Knoxville per week. Flights are available every day.
  • There are 221 United connecting flights from San Diego to Knoxville per week. Flights are available every day.
  • There are 175 Southwest connecting flights from San Diego to Knoxville per week. Flights are available every day.
  • There are 12 Frontier connecting flights from San Diego to Knoxville per week. Flights are available on Tuesday, Wednesday, Thursday, Friday and Sunday.
Use the Stops filter while searching for flights, to see only nonstop options in your results.
There are no direct flights from San Diego to Knoxville.
It's easy to find nonstop flights with Google Flights! Once you've searched for flights from San Diego to Knoxville, just select the nonstop flights only option in the 'Stops’ filter in the search form and view all available direct flights and their prices.
The cheapest business class round-trip flights between San Diego and Knoxville start at $535 from Mon, Jun 1 to Mon, Jun 8 with Frontier.
The cheapest economy class round-trip flights between San Diego and Knoxville start at $230 from Mon, Jun 1 to Mon, Jun 8.
To book business class trips from San Diego to Knoxville, look for the default Economy selection at the top, and change it to your desired cabin class such as Premium Economy, Business Class, or First Class. You can then select your departure and arrival dates, consider available options, and book your business travel.

You can also adjust the trip type to view one-way fares.
The best last-minute getaway deal for the next weekend between San Diego and Knoxville starts at $613 from Fri, May 8 to Sun, May 10 with Frontier.
The cheapest last-minute deal between San Diego and Knoxville at price $613 is offered by Frontier from Fri, May 8 to Sun, May 10.
To find last-minute flight deals from San Diego to Knoxville, start by entering the city names, select the desired departure and return dates, and hit the Search button to view flight options.

You can check for last-minute flights for the same day or adjust the trip type to see one-way fares.

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