Cheap flights from Madrid to Santa Cruz de la Sierra

Flights overview

Useful information for finding cheap flights from Madrid to Santa Cruz de la Sierra and booking your next trip
Cheapest round-trip flights $979
Air Europa Nonstop 12 hr Mon, May 25 — Tue, Jun 9
The cheapest round-trip flight from Madrid to Santa Cruz de la Sierra is currently $979
Cheapest one-way flight $479
LATAM 1 stop 33 hr Wed, May 6
The cheapest one-way flight from Madrid to Santa Cruz de la Sierra is currently $479
Last-minute weekend getaway $1,554
Air France, Gol 2 stops 25 hr Thu, May 7 — Mon, May 11
The cheapest last-minute weekend getaway from Madrid to Santa Cruz de la Sierra is currently $1,554
Cheapest business class flights $2,484
BoA Nonstop 11 hr Sun, Jun 7 — Sat, Jun 20
The cheapest business class round-trip flight from Madrid to Santa Cruz de la Sierra is currently $2,484
Fastest flight 11 hr The fastest nonstop flight from Madrid to Santa Cruz de la Sierra takes 11 hr
Nonstop flights Some days There are direct flights on this route 5 days a week: Mon, Wed, Fri, Sat, Sun.

When is the cheapest time to fly?

The cheapest month to fly from Madrid to Santa Cruz de la Sierra is typically April. The most expensive month to fly is typically December.
April
Cheapest
Typical prices: $750–1,150
December
Most expensive
Typical prices: $1,400–2,600

Popular airlines from Madrid to Santa Cruz de la Sierra

  • BoA
    Nonstop
    from $1,869
    Typical price: $1,550–3,050
    3 weekly nonstop flights
    MAD - VVI Every Wed, Fri, Sun
    28 weekly connecting flights
    MAD - VVI Every Tue
  • Air Europa
    Nonstop
    from $979
    Typical price: $1,150–2,150
    3 weekly nonstop flights
    MAD - VVI Every Mon, Wed, Sat
  • Avianca
    from $1,253
    Typical price: $940–1,900
    28 weekly connecting flights
    MAD - VVI Every day
  • LATAM
    from $1,096
    Typical price: $1,200–2,300
    12 weekly connecting flights
    MAD - VVI Every day

Popular airports near Madrid

  • Adolfo Suárez Madrid-Barajas Airport (MAD)
    Madrid Spain 33 min 9 mi
  • Valencia Airport (VLC)
    València Spain 3 hr 34 min 182 mi
  • Valladolid Airport (VLL)
    Valladolid Spain 2 hr 20 min 107 mi
  • Zaragoza Airport (ZAZ)
    Zaragoza Spain 3 hr 13 min 163 mi

Popular airports near Santa Cruz de la Sierra

  • Viru Viru International Airport (VVI) (VVI)
    Santa Cruz de la Sierra Bolivia 29 min 11 mi

Frequently asked questions about flying from Madrid to Santa Cruz de la Sierra

The cheapest flights from Madrid to Santa Cruz de la Sierra are usually in April. Typical ticket prices in April range from $750 to $1,150.
The cheapest round-trip flight from Madrid to Santa Cruz de la Sierra recently found on Google Flights was with Air Europa from $979. The cheapest one-way flight was with LATAM from $479.

Some of the cheapest round-trip deals we found with different airlines:
  • The cheapest BoA flight from Madrid to Santa Cruz de la Sierra is $1,869, flying from May 22 to Jun 6.
  • The cheapest Air Europa flight from Madrid to Santa Cruz de la Sierra is $979, flying from May 25 to Jun 9.
  • The cheapest Avianca flight from Madrid to Santa Cruz de la Sierra is $1,253, flying from Jun 5 to Jun 18.
  • The cheapest LATAM flight from Madrid to Santa Cruz de la Sierra is $1,096, flying from May 21 to Jun 4.
The cheapest round-trip flight from Madrid to Santa Cruz de la Sierra starts at $979 from Mon, May 25 to Tue, Jun 9. The cheapest one-way flight starts at $479 and departs on Wed, May 6.
11 hr is the shortest flight time from Madrid to Santa Cruz de la Sierra.
Santa Cruz de la Sierra is an all-year destination, with the most popular months being Dec–Jan. The tropical weather is warm-to-hot year-round, with the heaviest rainfall in Dec–Jan. Key annual events include Carnaval (Feb/Mar, dates vary), the Festival de Música Misiones de Chiquitos (Apr–May), celebrating American Renaissance and baroque music, and the city’s independence day (Sep 24).
It's easy to use Google Flights to find the cheapest days to fly from Madrid to Santa Cruz de la Sierra.
Just click the Departure label near the top of the page to open the calendar. Choose a start date and a return date to see how the round-trip fare changes on those specific days.
Adjust the trip type to see one-way fares. The cheapest available flights are highlighted and easy to spot. Once you settle on dates, click the Search button to see flight options and book the deal.

You can also turn on price tracking to get alerts if the price changes for a route or flight.
What counts as the best airline for your flights from Madrid to Santa Cruz de la Sierra really depends on your individual needs. You may have a favorite carrier or a loyalty program you like, but price, convenience, and airports served also come into play. Flexibility and booking terms – Can you change flights if you want to stay longer or get a refund if you have to postpone your trip? – are also factors that help determine which airline is best to fly from Madrid to Santa Cruz de la Sierra.

In terms of nonstop flights, BoA is the most popular. BoA offers 3 nonstop flights and 28 connecting flights per week. BoA flies from Adolfo Suárez Madrid-Barajas Airport (MAD) to Viru Viru International Airport (VVI) (VVI) .

Other popular airlines flying from Madrid to Santa Cruz de la Sierra are:
  • Air Europa offers 3 nonstop flights per week. Air Europa flies from Adolfo Suárez Madrid-Barajas Airport (MAD) to Viru Viru International Airport (VVI) (VVI) .
  • Avianca offers 28 connecting flights per week. Avianca flies from Adolfo Suárez Madrid-Barajas Airport (MAD) to Viru Viru International Airport (VVI) (VVI) .
  • LATAM offers 12 connecting flights per week. LATAM flies from Adolfo Suárez Madrid-Barajas Airport (MAD) to Viru Viru International Airport (VVI) (VVI) .
The number of connecting flights refers to distinct flights with at least one stop between Madrid and Santa Cruz de la Sierra.
The cheapest round-trip flight from Madrid to Santa Cruz de la Sierra recently found on Google Flights was with Air Europa from $979. The cheapest one-way flight was with LATAM from $479.

Some of the cheapest round-trip deals we found with different airlines:
  • The cheapest BoA flight from Madrid to Santa Cruz de la Sierra is $1,869, flying from May 22 to Jun 6.
  • The cheapest Air Europa flight from Madrid to Santa Cruz de la Sierra is $979, flying from May 25 to Jun 9.
  • The cheapest Avianca flight from Madrid to Santa Cruz de la Sierra is $1,253, flying from Jun 5 to Jun 18.
  • The cheapest LATAM flight from Madrid to Santa Cruz de la Sierra is $1,096, flying from May 21 to Jun 4.
BoA and Air Europa fly direct from Madrid to Santa Cruz de la Sierra.
  • There are 3 BoA direct flights from Madrid to Santa Cruz de la Sierra per week. Flights are available on Wednesday, Friday and Sunday.
  • There are 3 Air Europa direct flights from Madrid to Santa Cruz de la Sierra per week. Flights are available on Monday, Wednesday and Saturday.
Use the Stops filter while searching for flights, to see only nonstop options in your results.
The cheapest last-minute deal between Madrid and Santa Cruz de la Sierra at price $1,554 is offered by Air France, Gol from Thu, May 7 to Mon, May 11.
BoA and Air Europa fly direct from Madrid to Santa Cruz de la Sierra.
  • There are 3 BoA direct flights from Madrid to Santa Cruz de la Sierra per week. Flights are available on Wednesday, Friday and Sunday.
  • There are 3 Air Europa direct flights from Madrid to Santa Cruz de la Sierra per week. Flights are available on Monday, Wednesday and Saturday.
Use the Stops filter while searching for flights, to see only nonstop options in your results.
Direct flights from Madrid to Santa Cruz de la Sierra are only available on Monday, Wednesday, Friday, Saturday and Sunday.
The cheapest direct (nonstop) round-trip flights between Madrid and Santa Cruz de la Sierra start at $979 from Mon, May 25 to Tue, Jun 9 with Air Europa.
It's easy to find nonstop flights with Google Flights! Once you've searched for flights from Madrid to Santa Cruz de la Sierra, just select the nonstop flights only option in the 'Stops’ filter in the search form and view all available direct flights and their prices.
The cheapest business class round-trip flights between Madrid and Santa Cruz de la Sierra start at $2,484 from Sun, Jun 7 to Sat, Jun 20 with BoA.
The cheapest economy class round-trip flights between Madrid and Santa Cruz de la Sierra start at $979 from Mon, May 25 to Tue, Jun 9.
To book business class trips from Madrid to Santa Cruz de la Sierra, look for the default Economy selection at the top, and change it to your desired cabin class such as Premium Economy, Business Class, or First Class. You can then select your departure and arrival dates, consider available options, and book your business travel.

You can also adjust the trip type to view one-way fares.
The best last-minute getaway deal for the next weekend between Madrid and Santa Cruz de la Sierra starts at $1,554 from Thu, May 7 to Mon, May 11 with Air France, Gol.
The cheapest last-minute deal between Madrid and Santa Cruz de la Sierra at price $1,554 is offered by Air France, Gol from Thu, May 7 to Mon, May 11.
To find last-minute flight deals from Madrid to Santa Cruz de la Sierra, start by entering the city names, select the desired departure and return dates, and hit the Search button to view flight options.

You can check for last-minute flights for the same day or adjust the trip type to see one-way fares.

Search more flights

Popular trips from Madrid

  1. London
    $47
    May 21 — Jun 3
    Nonstop 2 hr 25 min Ryanair
  2. Barcelona
    $84
    Oct 23 — Nov 6
    Nonstop 1 hr 15 min Iberia
  3. Lisbon
    $42
    Jun 15 — Jun 30
    Nonstop 1 hr 30 min Ryanair
  4. Paris
    $69
    Sep 24 — Oct 8
    Nonstop 2 hr 10 min Ryanair

Find cheap flights from Madrid to anywhere

Find cheap flights on popular routes