Find Cheap Flights from Medellín to Santiago (MDE - SCL)

Flights overview

Useful information for finding cheap flights from Medellín to Santiago and booking your next trip

Cheapest round-trip flights	$444	JetSMART Nonstop 7 hr Sun, Jul 19 — Tue, Jul 28	The cheapest round-trip flight from Medellín to Santiago is currently $444
Cheapest one-way flight	$245	JetSMART Nonstop 7 hr Sun, Jun 7	The cheapest one-way flight from Medellín to Santiago is currently $245
Last-minute weekend getaway	$485	JetSMART Nonstop 7 hr Fri, May 8 — Sun, May 10	The cheapest last-minute weekend getaway from Medellín to Santiago is currently $485
Cheapest business class flights	$1,093	COPA 1 stop 14 hr Thu, Jun 4 — Wed, Jun 10	The cheapest business class round-trip flight from Medellín to Santiago is currently $1,093

Fastest flight	6 hr 10 min	The fastest nonstop flight from Medellín to Santiago takes 6 hr 10 min
Nonstop flights	Some days	There are direct flights on this route 4 days a week: Mon, Thu, Fri, Sun.

When is the cheapest time to fly?

The cheapest month to fly from Medellín to Santiago is typically April. The most expensive month to fly is typically February.

April Cheapest	Typical prices: $365–510
February Most expensive	Typical prices: $460–630

Popular airlines from Medellín to Santiago

JetSMART

Nonstop

from $441

Typical price: $410–610

4 weekly nonstop flights

MDE - SCL Every Mon, Thu, Fri, Sun

42 weekly connecting flights

MDE - SCL Every day
LATAM

from $499

Typical price: $445–690

238 weekly connecting flights

MDE - SCL Every day
Avianca

from $543

Typical price: $465–820

234 weekly connecting flights

MDE - SCL Every day
COPA

from $501

Typical price: $455–890

201 weekly connecting flights

MDE - SCL Every day
American

14 weekly connecting flights

MDE - SCL Every day

Popular airports near Medellín

Jose Maria Cordova International Airport (MDE)

Medellín Colombia 41 min 11 mi
Olaya Herrera Airport (EOH)

Medellín Colombia 16 min 2 mi
El Dorado International Airport (BOG)

Bogotá Colombia 8 hr 41 min 144 mi
Aeropuerto Internacional Matecaña (PEI)

Pereira Colombia 4 hr 20 min 99 mi

Popular airports near Santiago

Arturo Merino Benitez International Airport (SCL)

Santiago Chile 27 min 8 mi

Frequently asked questions about flying from Medellín to Santiago

The cheapest flights from Medellín to Santiago are usually in April. Typical ticket prices in April range from $365 to $510.

The cheapest round-trip flight from Medellín to Santiago recently found on Google Flights was with JetSMART from $444. The cheapest one-way flight was with JetSMART from $245.

Some of the cheapest round-trip deals we found with different airlines:

The cheapest JetSMART flight from Medellín to Santiago is $441, flying from Jun 7 to Jun 13.
The cheapest LATAM flight from Medellín to Santiago is $499, flying from May 28 to Jun 3.
The cheapest Avianca flight from Medellín to Santiago is $543, flying from May 14 to May 22.
The cheapest COPA flight from Medellín to Santiago is $501, flying from May 28 to Jun 3.

The cheapest round-trip flight from Medellín to Santiago starts at $444 from Sun, Jul 19 to Tue, Jul 28. The cheapest one-way flight starts at $245 and departs on Sun, Jun 7.

6 hr 10 min is the shortest flight time from Medellín to Santiago.

Peak season is summer (Nov–Apr). Temperatures are mild year-round, but winter (May–Sep) sees frequent rain (snow in the Andes). The Santiago a Mil international theater festival takes place in Jan, as well as the Festival Nacional del Folklore, a days-long festival of traditional Chilean music and dance in the suburb of San Bernardo. The Fiesta del Vino (Apr) celebrates the fall grape harvest in the nearby wine capital of Pirque. The Fiestas Patrias (Sep) mark Chile’s freedom from Spanish rule.

It's easy to use Google Flights to find the cheapest days to fly from Medellín to Santiago.
Just click the Departure label near the top of the page to open the calendar. Choose a start date and a return date to see how the round-trip fare changes on those specific days.
Adjust the trip type to see one-way fares. The cheapest available flights are highlighted and easy to spot. Once you settle on dates, click the Search button to see flight options and book the deal.

You can also turn on price tracking to get alerts if the price changes for a route or flight.

What counts as the best airline for your flights from Medellín to Santiago really depends on your individual needs. You may have a favorite carrier or a loyalty program you like, but price, convenience, and airports served also come into play. Flexibility and booking terms – Can you change flights if you want to stay longer or get a refund if you have to postpone your trip? – are also factors that help determine which airline is best to fly from Medellín to Santiago.

In terms of nonstop flights, JetSMART is the most popular. JetSMART offers 4 nonstop flights and 42 connecting flights per week. JetSMART flies from Jose Maria Cordova International Airport (MDE) to Arturo Merino Benitez International Airport (SCL) .

In terms of flights, LATAM is the most popular. LATAM offers 238 connecting flights per week. LATAM flies from Jose Maria Cordova International Airport (MDE) to Arturo Merino Benitez International Airport (SCL) .

Other popular airlines flying from Medellín to Santiago are:

Avianca offers 234 connecting flights per week. Avianca flies from Jose Maria Cordova International Airport (MDE) to Arturo Merino Benitez International Airport (SCL) .
COPA offers 201 connecting flights per week. COPA flies from Jose Maria Cordova International Airport (MDE) to Arturo Merino Benitez International Airport (SCL) .
American offers 14 connecting flights per week. American flies from Jose Maria Cordova International Airport (MDE) to Arturo Merino Benitez International Airport (SCL) .

The number of connecting flights refers to distinct flights with at least one stop between Medellín and Santiago.

The cheapest round-trip flight from Medellín to Santiago recently found on Google Flights was with JetSMART from $444. The cheapest one-way flight was with JetSMART from $245.

Some of the cheapest round-trip deals we found with different airlines:

The cheapest JetSMART flight from Medellín to Santiago is $441, flying from Jun 7 to Jun 13.
The cheapest LATAM flight from Medellín to Santiago is $499, flying from May 28 to Jun 3.
The cheapest Avianca flight from Medellín to Santiago is $543, flying from May 14 to May 22.
The cheapest COPA flight from Medellín to Santiago is $501, flying from May 28 to Jun 3.

JetSMART flies direct from Medellín to Santiago.

There are 4 JetSMART direct flights from Medellín to Santiago per week. Flights are available on Monday, Thursday, Friday and Sunday.

Use the Stops filter while searching for flights, to see only nonstop options in your results.

The cheapest last-minute deal between Medellín and Santiago at price $485 is offered by JetSMART from Fri, May 8 to Sun, May 10.

JetSMART flies direct from Medellín to Santiago.

There are 4 JetSMART direct flights from Medellín to Santiago per week. Flights are available on Monday, Thursday, Friday and Sunday.

Use the Stops filter while searching for flights, to see only nonstop options in your results.

Direct flights from Medellín to Santiago are only available on Monday, Thursday, Friday and Sunday.

The cheapest direct (nonstop) round-trip flights between Medellín and Santiago start at $444 from Sun, Jul 19 to Tue, Jul 28 with JetSMART.

It's easy to find nonstop flights with Google Flights! Once you've searched for flights from Medellín to Santiago, just select the nonstop flights only option in the 'Stops’ filter in the search form and view all available direct flights and their prices.

The cheapest business class round-trip flights between Medellín and Santiago start at $1,093 from Thu, Jun 4 to Wed, Jun 10 with COPA.

The cheapest economy class round-trip flights between Medellín and Santiago start at $444 from Sun, Jul 19 to Tue, Jul 28.

To book business class trips from Medellín to Santiago, look for the default Economy selection at the top, and change it to your desired cabin class such as Premium Economy, Business Class, or First Class. You can then select your departure and arrival dates, consider available options, and book your business travel.

You can also adjust the trip type to view one-way fares.

The best last-minute getaway deal for the next weekend between Medellín and Santiago starts at $485 from Fri, May 8 to Sun, May 10 with JetSMART.

The cheapest last-minute deal between Medellín and Santiago at price $485 is offered by JetSMART from Fri, May 8 to Sun, May 10.

To find last-minute flight deals from Medellín to Santiago, start by entering the city names, select the desired departure and return dates, and hit the Search button to view flight options.

You can check for last-minute flights for the same day or adjust the trip type to see one-way fares.