トム・ド・サヴォワ Tomme de Savoie は硬めのチーズ。皮は捨て、中身を薄切りで味わうのが風流。冷蔵庫で保存。結構長持ちしますので少しづつ出しては食べます。くせがなく、口の中で芳香豊かに味わえます。サヴォワ地方は一度行きましたが、緩やかな山々に放牧された牛たちがのんびりと過ごし、山の地平線に牛の姿が見えた時はさすがに驚きました。フランス人に愛されるチーズの一つです。
Cet article met en évidence une transformation de l'ARN du vaccin ... en ADN dans des cultures de cellules hépatiques, posant la question de leur intégration dans le génome.
ラウルト博士が読んだスエーデンの Lund University (Clinical Science) の臨床科学の論文はMDPI
という学術論文出版社のサイトで2022年25日に掲載された。下記は英語の「要約」部分↓
Abstract
Preclinical studies of COVID-19 mRNA vaccine BNT162b2, developed by Pfizer and BioNTech, showed reversible hepatic effects in animals that received the BNT162b2 injection. Furthermore, a recent study showed that SARS-CoV-2 RNA can be reverse-transcribed and integrated into the genome of human cells. In this study, we investigated the effect of BNT162b2 on the human liver cell line Huh7 in vitro. Huh7 cells were exposed to BNT162b2, and quantitative PCR was performed on RNA extracted from the cells. We detected high levels of BNT162b2 in Huh7 cells and changes in gene expression of long interspersed nuclear element-1 (LINE-1), which is an endogenous reverse transcriptase. Immunohistochemistry using antibody binding to LINE-1 open reading frame-1 RNA-binding protein (ORFp1) on Huh7 cells treated with BNT162b2 indicated increased nucleus distribution of LINE-1. PCR on genomic DNA of Huh7 cells exposed to BNT162b2 amplified the DNA sequence unique to BNT162b2. Our results indicate a fast up-take of BNT162b2 into human liver cell line Huh7, leading to changes in LINE-1 expression and distribution. We also show that BNT162b2 mRNA is reverse transcribed intracellularly into DNA in as fast as 6 h upon BNT162b2 exposure.
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