Moabac
Mecanismo de acción de moléculas con actividad biológica - Mechanisms of action of biolocally active compounds
Publicaciones ( 76 )
2026
- Mechanism of cyanobacterial ferredoxin-dependent flavin thioredoxin reductase reveals thiolate-FAD charge transfer and catalytic asymmetry in a homodimer
FEBS Journal, Vol. 293, Núm. 1, pp. 96-112
- The oncogenic CCDC6-RET fusion protein is a dual ATP- and ADP-dependent kinase
Nature Communications , Vol. 17, Núm. 1
2025
- A New GlyT2 Variant Associated with Hyperekplexia
International Journal of Molecular Sciences, Vol. 26, Núm. 14
- A Tetrapodal Tryptophan Derivative with Multiple Exposed Free Carboxylic Acids Blocks Host Cell Entry of Omicron SARS-Cov-2 and Respiratory Syncytial Virus
ACS Omega, Vol. 10, Núm. 46, pp. 56830-56844
- A π-stacking gate for redox control in flavin ferredoxin-thioredoxin reductases
International Journal of Biological Macromolecules, Vol. 333
- Assessing the Impact of Depth Data on Human Kinematics: A Hybrid RGB-D and MediaPipe Method
IEEE International Symposium on Medical Measurements and Applications, MeMeA
- Discovery of a Baloxavir-Inspired Endonuclease Inhibitor That Prevents Herpes Simplex Virus 1 Replication in Cell Culture and In Vivo
Advanced Science, Vol. 12, Núm. 42
- Fundamentos de la interacción fármaco-receptor
Velázquez, farmacología básica y clínica (Editorial Médica Panamericana), pp. 55-66
2024
- A distinctive family of L,D-transpeptidases catalyzing L-Ala-mDAP crosslinks in Alpha- and Betaproteobacteria
Nature Communications, Vol. 15, Núm. 1
- Antiviral Agents: Structural Basis of Action and Rational Design
Subcellular Biochemistry (Springer Science and Business Media B.V.), pp. 745-784
- Characterization of VldE (Spr1875), a Pneumococcal Two-State l,d-Endopeptidase with a Four-Zinc Cluster in the Active Site
ACS Catalysis, Vol. 14, Núm. 24, pp. 18786-18798
- Flexible structural arrangement and DNA-binding properties of protein p6 from Bacillus subtillis phage ?29
Nucleic Acids Research, Vol. 52, Núm. 4, pp. 2045-2065
- The repertoire of iron superoxide dismutases from Leishmania infantum as targets in the search for therapeutic agents against leishmaniasis
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol. 39, Núm. 1
2023
- Alternative Approaches to Understand Microtubule Cap Morphology and Function
ACS Omega, Vol. 8, Núm. 4, pp. 3540-3550
- Chemical modulation of microtubule structure through the laulimalide/peloruside site
Structure, Vol. 31, Núm. 1, pp. 88-99.e5
- Computational Approaches to Enzyme Inhibition by Marine Natural Products in the Search for New Drugs
Marine Drugs, Vol. 21, Núm. 2
- Insertion of an Amphipathic Linker in a Tetrapodal Tryptophan Derivative Leads to a Novel and Highly Potent Entry Inhibitor of Enterovirus A71 Clinical Isolates
International Journal of Molecular Sciences, Vol. 24, Núm. 4
- Modulation of taxane binding to tubulin curved and straight conformations by systematic 3′N modification provides for improved microtubule binding, persistent cytotoxicity and in vivo potency
European Journal of Medicinal Chemistry, Vol. 259
- Molecular basis of the final step of cell division in Streptococcus pneumoniae
Cell Reports, Vol. 42, Núm. 7
- Next generation of selenocyanate and diselenides with upgraded leishmanicidal activity
Bioorganic Chemistry, Vol. 138
