CLEVELAND — The Guardians open a four-game series with the Baltimore Orioles July 21 at Progressive field.
The Guardians won their first series after the All-Star break , 2-1 over the Athletics. The Orioles come into Cleveland as one of the biggest underperforming teams of the 2025 season at 44-54 and in last place in the American League East.
Guardians All-Star left fielder Steven Kwan , who has been working through a wrist issue , is back in the lineup and in the leadoff spot.
Follow along here for live score updates, analysis and highlights from the July 21 game between the Guardians and Orioles at Progressive Field.
Guardians beat the Orioles
The Guardians have beaten the Orioles 10-5. Cleveland is 3-1 to begin the second half of the season.
Guardians lead Orioles in 7th inning
Tanner Bibee was knocked around early, but he's been able to grind his way through the seventh inning with the Guardians leading 6-5.
Bibee has allowed five runs (three earned) with four strikeouts in seven innings. Cade Smith is warming for Cleveland.
Kyle Manzardo hits go-ahead home run vs Orioles
The Guardians have their first lead of the night courtesy of a Kyle Manzardo solo home run that he pulled over the right-field fence in the sixth inning. That's his 16th home run of the season.
Guardians rally for 4-run 7th inning to take 5-run lead over Orioles
Grant Wolfram had a really tough inning on the mound, and the Guardians have taken a 10-5 lead with a four-run seventh-inning rally.
The Guardians loaded the bases and didn't have to do much for a bit. Wolfram walked Nolan Jones and then Daniel Schneemann to score two of the four runs in the inning. Brayan Rocchio followed with a two-run single to left field giving the Guardians bullpen some breathing room.
This is the type of counter-punch the Guardians just didn't have for most of June.
Guardians, Orioles score: Bo Naylor ties it with first home run in more than a month
For the first time since June 9, Bo Naylor has hit a home run.
Naylor's first homer in more than a month, a solo shot to right-center field, has tied it 5-5. The Orioles have twice taken the lead, and the Guardians have twice tied it back up relatively quickly.
Naylor has been one of the least productive hitters in all of baseball over the last month, hitting just .116 during that time.
Carlos Santana RBI single cuts into Orioles lead
With two on, Carlos Santana added an RBI single to right field, and it's now 5-4 Orioles in the fourth inning.
Ramon Laureano crushes go-ahead home run off Tanner Bibee
Ramon Laureano is tormenting Tanner Bibee and the Guardians tonight.
Already with a two-run single, Laureano in the third inning launched a go-ahead, two-run home run to left field, a 425 no-doubter that has the Orioles on top 5-3.
Bibee has been off tonight, to say the least, as the Orioles already have five runs on five hits. Laureano actually missed and fouled off two pitches that caught the middle of the plate before drilling the home run.
Jose Ramirez hits 3-run home run, reaches 20-20 season; Guardians, Orioles score update
The Guardians answered the Orioles' three-run inning within their first three batters of the first inning.
Steven Kwan, back in the lineup after missing the last three games with a wrist issue, led off with a walk. Angel Martinez followed with a single to set up Jose Ramirez, who drilled a three-run home run to tie it, 3-3.
That was Ramirez's 20th home run of the season, giving him the seventh 20-homer, 20-steals season of his career and the fifth consecutive.
Guardians, Orioles score: Baltimore puts up 3-run first inning against Tanner Bibee
The Orioles jumped all over Tanner Bibee in the first inning.
Jackson Holliday , Jordan Westburg and Gunnar Henderson all singled to open the game, with the latter bringing him the first run of the night. With one out, former Guardians outfielder Ramon Laureano added a two-run single to make it a 3-0 Orioles lead.
Below is some pregame information.
MLB Standings: American League Central
The American League Central Division standings entering July 21:
-
Tigers 60-40
-
Guardians 48-50 (11)
-
Twins 48-51 (11.5)
-
Royals 48-52 (12)
-
White Sox 35-65 (25)
Guardians schedule | Upcoming games
The Guardians and Baltimore Orioles will play a four-game series at Progressive Field to finish Cleveland's homestand. The Guardians then head on the road for a quick series in Kansas City against the Royals.
How can I watch, stream or listen to the Guardians vs Orioles game?
The game on July 21 can be viewed locally on AT&T U-verse (channel 1736), COX (channel 80), DIRECTV Satellite and Streaming (channel 662), FuboTV and Spectrum (channel 1306). It can also be streamed via MLB's direct-to-consumer streaming subscription ( CLEGuardians.TV ). And it'll be available on the radio via WTAM 1100, WMMS 100.7 and WARF 1350.
President Trump calls for Guardians to change team name back
President Trump, in a post on Truth Social, again called for the Guardians to revert their team name back to the former name.
This article originally appeared on Akron Beacon Journal: Guardians score, lineup today vs Orioles live updates, highlights

