Texas, Miami on upset alert? College football bold predictions for Week 6

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Texas, Miami on upset alert? College football bold predictions for Week 6

Texas, Miami on upset alert? College football bold predictions for Week 6

USA TODAY · USA TODAY Sports

Sat, Oct 4, 2025 ·

4 min read

Billy Napier, Florida take down Texas , Arch Manning

The hottest of hot seats may belong to Billy Napier, but it's about to get cooler. The Florida coach always seems to perform best with his back up against the wall and this week's matchup against No. 7 Texas with his team 1-3 qualfies. The Longhorns , meanwhile, might be looking ahead to next week's showdown with Oklahoma . Expect the home crowd to be a factor and a strong defense that harasses Arch Maning to be pivotal as Florida gets to celebrate a big win. -- Matt Hayes

Penn State damages CFP hopes against UCLA

We know Penn State can't win big games, but they sure can take those gimme ones. The Nittany Lions head West to take on winless UCLA in what will likely be a Rose Bowl filled with more visiting fans. However, it won't be a cakewalk. Playing with nothing to lose, UCLA actually makes things interesting and forces Penn State to play all four quarters. While the Nittany Lions win, the performance against one of the worst teams in the country won't help the argument this team deserves to be in the playoff conversation. -- Jordan Mendoza

Cincinnati continues upset run with Iowa State win

Cincinnati stays hot and beats Iowa State to throw the Big 12 race into further chaos. In addition to moving the Bearcats up the standings, a marquee win against the Cyclones would go a long way toward securing another year for coach Scott Satterfield. UC has been very good all year and particularly the past three games, rebounding from a narrow loss to Nebraska in the opener to look like one of the top offenses in the conference. Few quarterbacks have been playing better than Brendan Sorsby . -- Paul Myerberg

Florida State bounces back with defeat of Miami

A week ago, the Seminoles were getting exposed on defense while getting beat on the road at Virginia . So conventional wisdom would be that a visit from the rival Hurricanes would go poorly this week. But that loss actually might work in Florida State's favor by getting them refocused and Miami overconfident. The Hurricanes have risen into the top five but haven't yet gone on the road. We'll see how good Carson Beck and the rest of the team function in a tough environment. The bet is they won't pass the test. -- Erick Smith

Virginia stumbles at Louisville after Florida State win

Let's give credit where due. Virginia's victory against Florida State was a true program changer, a much needed ray of light for a team that has struggled for relevance for years amid a multitude of issues on and off the field.

But sometimes in college football, winning the game after the game is the hardest thing, and the Cavaliers are about to learn this lesson at unbeaten Louisville. The Cardinals had to work a bit harder than they'd have liked to get out of Pittsburgh with a win last week, and they'll be very happy to be back at home. Add in the uncertainty of UVa quarterback Chandler Morris's hand injury, and Saturday shapes up to be a back down to earth affair for the Cavaliers as the Cardinals stay undefeated for another week. -- Eddie Timanus

Another rough day for UCLA, Nico Iamaleava

Nico Iamaleava, aka "Mr. April," will continue his quest to become "Mr. Winless" at UCLA after taking a pay cut to leave Tennessee , a playoff contender. Penn State heads west with a perfect opportunity to lick their wounds while basking in some sunshine and playing in front of a friends-and-family crowd at the Rose Bowl. Drew Allar might never look closer to a first-round NFL pick than he does in this get-right game against UCLA. Meanwhile, Iamaleava has a good chance to throw for at least 85 yards. -- Blake Toppmeyer