He is the second starting offensive lineman to head to the IR.
This comes afterCardinals head coach Mike LaFleur ruled Adams outfor this week on Oct. 7, and after LaFleur announced that starting left tackle Paris Johnson Jr. is out for the rest of the season on Oct. 5. Adams will miss at least a month.
Arizona Cardinals wide receiver Marvin Harrison Jr. (18) is lifted in the air by his teammates after scoring the first touchdown of the game against the New York Giants on Oct. 4, 2026, in East Rutherford, New Jersey.
(Kevin R. Wexler/NorthJersey.com)
Arizona Cardinals wide receiver Marvin Harrison Jr. (18) attempts to make a catch over San Francisco 49ers defensive back Deommodore Lenoir (2) in the first half at Levi's Stadium in Santa Clara, California, on Sept. 27, 2026.
(Darren Yamashita/Imagn Images)
Arizona Cardinals wide receiver Marvin Harrison Jr. (18) celebrates with tight end Teagan Quitoriano (47) after catching a touchdown pass during the first quarter of a preseason game against the Las Vegas Raiders at Allegiant Stadium on Aug. 13, 2026.
(David Brytus/Imagn Images)
Arizona Cardinals wide receiver Marvin Harrison Jr. (18) catches a 7-yard touchdown pass against Las Vegas Raiders cornerback Darien Porter (26) in the first half at Allegiant Stadium on Aug. 13, 2026.
(Kirby Lee/Imagn Images)
Arizona Cardinals wide receiver Marvin Harrison Jr. (18) celebrates with tight end Trey McBride (85) after scoring a touchdown against the Dallas Cowboys in the first half at AT&T Stadium on Nov. 3, 2025.
(Kevin Jairaj/Imagn Images)
Arizona Cardinals receiver Marvin Harrison Jr. (18) catches a touchdown over cornerback Max Melton (16) during their training camp red and white practice at State Farm Stadium in Glendale on Aug. 9, 2026.
(Joe Rondone/The Republic)
Arizona Cardinals wide receiver Marvin Harrison Jr. (18) catches a touchdown pass as Minnesota Vikings cornerback Fabian Moreau (23) defends during the third quarter at U.S. Bank Stadium in Minneapolis on Dec. 1, 2024.
(Jeffrey Becker/Imagn Images)
Arizona Cardinals receiver Marvin Harrison Jr. signs autographs for fans during training camp at State Farm Stadium in Glendale on Aug. 2, 2026.
(Joe Rondone/The Republic)
Arizona Cardinals wide receiver Marvin Harrison Jr. (18) catches a touchdown pass against Los Angeles Rams cornerback Tre'Davious White (27) during the first half at State Farm Stadium in Glendale on Sept. 15, 2024.
(Joe Camporeale/Imagn Images)
Marvin Harrison Jr. #18 of the Arizona Cardinals is unable to catch the ball against the Tampa Bay Buccaneers during the third quarter at Raymond James Stadium on Nov. 30, 2025, in Tampa, Florida.
(Mike Ehrmann/Getty Images)
Marvin Harrison Jr. talks with the media in the locker room at Dignity Health Arizona Cardinals Training Center in Tempe on Jan. 5, 2026.
(Mark Henle/The Republic)
Ohio State Buckeyes wide receiver Marvin Harrison Jr. stands on the red carpet ahead of the 2024 NFL Draft at Detroit’s Fox Theatre.
(Kirby Lee, Kirby Lee-USA TODAY Sports)
NFL draft prospect Marvin Harrison Jr., a wide receiver who played at Ohio State, walks the red carpet for NFL draft day at the Fox Theatre in Detroit on Thursday, April 25, 2024.
(Kimberly P. Mitchell/USA Today)
Marvin Harrison Jr. celebrates after being selected fourth overall by the Arizona Cardinals during the first round of the 2024 NFL Draft at Campus Martius Park and Hart Plaza on April 25, 2024 in Detroit.
(Gregory Shamus/Getty Images)
Marvin Harrison Jr. celebrates after being selected fourth overall by the Arizona Cardinals during the first round of the 2024 NFL Draft at Campus Martius Park and Hart Plaza on April 25, 2024 in Detroit.
(Gregory Shamus/Getty Images)
(L-R) Marvin Harrison Jr. poses with NFL Commissioner Roger Goodell after being selected fourth overall by the Arizona Cardinals during the first round of the 2024 NFL Draft at Campus Martius Park and Hart Plaza on April 25, 2024 in Detroit.
(Gregory Shamus/Getty Images)
Marvin Harrison Jr. #18 of the Ohio State Buckeyes makes a one-handed catch next to Will Johnson #2 of the Michigan Wolverines at Michigan Stadium on Nov. 25, 2023 in Ann Arbor, Michigan.
(Gregory Shamus/Getty Images)
Ohio State Buckeyes wide receiver Marvin Harrison Jr. (18) warms up prior to the NCAA football game against the Minnesota Golden Gophers at Ohio Stadium.
(Adam Cairns/USA Today)
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Marvin Harrison Jr.'s Arizona Cardinals career at a glance
Arizona Cardinals wide receiver Marvin Harrison Jr. (18) is lifted in the air by his teammates after scoring the first touchdown of the game against the New York Giants on Oct. 4, 2026, in East Rutherford, New Jersey.
(Kevin R. Wexler/NorthJersey.com)
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Marvin Harrison Jr.'s Arizona Cardinals career at a glance
Arizona Cardinals wide receiver Marvin Harrison Jr. (18) is lifted in the air by his teammates after scoring the first touchdown of the game against the New York Giants on Oct. 4, 2026, in East Rutherford, New Jersey.
(Kevin R. Wexler/NorthJersey.com)
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Marvin Harrison Jr.'s Arizona Cardinals career at a glance
Arizona Cardinals wide receiver Marvin Harrison Jr. (18) attempts to make a catch over San Francisco 49ers defensive back Deommodore Lenoir (2) in the first half at Levi's Stadium in Santa Clara, California, on Sept. 27, 2026.
(Darren Yamashita/Imagn Images)
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Marvin Harrison Jr.'s Arizona Cardinals career at a glance
Arizona Cardinals wide receiver Marvin Harrison Jr. (18) celebrates with tight end Teagan Quitoriano (47) after catching a touchdown pass during the first quarter of a preseason game against the Las Vegas Raiders at Allegiant Stadium on Aug. 13, 2026.
(David Brytus/Imagn Images)
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Marvin Harrison Jr.'s Arizona Cardinals career at a glance
Arizona Cardinals wide receiver Marvin Harrison Jr. (18) catches a 7-yard touchdown pass against Las Vegas Raiders cornerback Darien Porter (26) in the first half at Allegiant Stadium on Aug. 13, 2026.
(Kirby Lee/Imagn Images)
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Marvin Harrison Jr.'s Arizona Cardinals career at a glance
Arizona Cardinals wide receiver Marvin Harrison Jr. (18) celebrates with tight end Trey McBride (85) after scoring a touchdown against the Dallas Cowboys in the first half at AT&T Stadium on Nov. 3, 2025.
(Kevin Jairaj/Imagn Images)
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Marvin Harrison Jr.'s Arizona Cardinals career at a glance
Arizona Cardinals receiver Marvin Harrison Jr. (18) catches a touchdown over cornerback Max Melton (16) during their training camp red and white practice at State Farm Stadium in Glendale on Aug. 9, 2026.
(Joe Rondone/The Republic)
7/18
Marvin Harrison Jr.'s Arizona Cardinals career at a glance
Arizona Cardinals wide receiver Marvin Harrison Jr. (18) catches a touchdown pass as Minnesota Vikings cornerback Fabian Moreau (23) defends during the third quarter at U.S. Bank Stadium in Minneapolis on Dec. 1, 2024.
(Jeffrey Becker/Imagn Images)
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Marvin Harrison Jr.'s Arizona Cardinals career at a glance
Arizona Cardinals receiver Marvin Harrison Jr. signs autographs for fans during training camp at State Farm Stadium in Glendale on Aug. 2, 2026.
(Joe Rondone/The Republic)
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Marvin Harrison Jr.'s Arizona Cardinals career at a glance
Arizona Cardinals wide receiver Marvin Harrison Jr. (18) catches a touchdown pass against Los Angeles Rams cornerback Tre'Davious White (27) during the first half at State Farm Stadium in Glendale on Sept. 15, 2024.
(Joe Camporeale/Imagn Images)
10/18
Marvin Harrison Jr.'s Arizona Cardinals career at a glance
Marvin Harrison Jr. #18 of the Arizona Cardinals is unable to catch the ball against the Tampa Bay Buccaneers during the third quarter at Raymond James Stadium on Nov. 30, 2025, in Tampa, Florida.
(Mike Ehrmann/Getty Images)
11/18
Marvin Harrison Jr.'s Arizona Cardinals career at a glance
Marvin Harrison Jr. talks with the media in the locker room at Dignity Health Arizona Cardinals Training Center in Tempe on Jan. 5, 2026.
(Mark Henle/The Republic)
12/18
Marvin Harrison Jr.'s Arizona Cardinals career at a glance
Ohio State Buckeyes wide receiver Marvin Harrison Jr. stands on the red carpet ahead of the 2024 NFL Draft at Detroit’s Fox Theatre.
(Kirby Lee, Kirby Lee-USA TODAY Sports)
13/18
Marvin Harrison Jr.'s Arizona Cardinals career at a glance
NFL draft prospect Marvin Harrison Jr., a wide receiver who played at Ohio State, walks the red carpet for NFL draft day at the Fox Theatre in Detroit on Thursday, April 25, 2024.
(Kimberly P. Mitchell/USA Today)
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Marvin Harrison Jr.'s Arizona Cardinals career at a glance
Marvin Harrison Jr. celebrates after being selected fourth overall by the Arizona Cardinals during the first round of the 2024 NFL Draft at Campus Martius Park and Hart Plaza on April 25, 2024 in Detroit.
(Gregory Shamus/Getty Images)
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Marvin Harrison Jr.'s Arizona Cardinals career at a glance
Marvin Harrison Jr. celebrates after being selected fourth overall by the Arizona Cardinals during the first round of the 2024 NFL Draft at Campus Martius Park and Hart Plaza on April 25, 2024 in Detroit.
(Gregory Shamus/Getty Images)
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Marvin Harrison Jr.'s Arizona Cardinals career at a glance
(L-R) Marvin Harrison Jr. poses with NFL Commissioner Roger Goodell after being selected fourth overall by the Arizona Cardinals during the first round of the 2024 NFL Draft at Campus Martius Park and Hart Plaza on April 25, 2024 in Detroit.
(Gregory Shamus/Getty Images)
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Marvin Harrison Jr.'s Arizona Cardinals career at a glance
Marvin Harrison Jr. #18 of the Ohio State Buckeyes makes a one-handed catch next to Will Johnson #2 of the Michigan Wolverines at Michigan Stadium on Nov. 25, 2023 in Ann Arbor, Michigan.
(Gregory Shamus/Getty Images)
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Marvin Harrison Jr.'s Arizona Cardinals career at a glance
Ohio State Buckeyes wide receiver Marvin Harrison Jr. (18) warms up prior to the NCAA football game against the Minnesota Golden Gophers at Ohio Stadium.
(Adam Cairns/USA Today)
Adams will be the Cardinals' third pick of the 2024 NFL Draft to miss at least a month this season, as running back Trey Benson was waived with an injury designation before the season and tight end Tip Reiman has remained on the Physically Unable to Perform (PUP) list all season.
Backup right guard Jon Gaines II will likely step in against theDetroit Lionsthis week. The Cardinals' 2023 fourth-rounder played38 snaps for the Cardinalslast week due to Adams' injury limiting him to 28. Gaines has started six games in his four-year NFL career (all four years with the Cardinals).
Detroit's defense heads to Arizona for this Week 5 matchup, averaging 3.8 sacks per game, which ranks second in the NFL.