Arsenal star Bukayo Saka left their UEFA Champions League game against Bayern Munich after just 10 minutes on Wednesday at the Allianz Arena.
Saka, 25, grabbed at his upper leg following a pass against Bayern, and left the game after a few more minutes.
Eberechi Eze took Saka's place in the pitch.
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Arteta's initial post-match comments braced for "really bad news," and he added more.
"Against Lille, he didn't start the game. Then he started the game at the weekend. And then it's very early in this game."
"The level of intensity these games require is something incredible. You could see last night what happened in the PSG-Barcelona game. This is man-to-man for 96 minutes. Every action. There's no breathing."
"The strength, the quality, the attention, the level that you need is unbelievable because it's the highest level. Those things happen unfortunately. It doesn't look good at all but we have to wait and see."
Bukayo Saka injury update, history: Arsenal manager Arteta to be without Saka for weeks
Arteta is not expecting Saka back any time soon, the Spaniard revealed in his Friday press conference ahead of the Gunners' Week 8 match versus Everton.
"He's got another MRI [on Friday] because he had quite a lot of fluid in the area so it was difficult to understand the extent of the injury, but we'll know more probably tomorrow." Arteta said, via Arsenal.com .
"Again, we need a few more scans and opinions from the specialist. Obviously when a player has to walk off the pitch, he's struggling to walk without any pain, he's restricted to movement, they are not good signs."
"So again, let's be a little bit patient so we can give a definitive assessment and then let you know."
Saka missed time on three different occasions last Premier League season:
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Weeks 3 and 4 with a hamstring injury
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Weeks 24 and 25 with a hip problem
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Weeks 32 and 33 with a sore achilles
The first and last of those injuries also saw him miss one Champions League league phase game at Athletic Bilbao and both legs of the quarterfinals versus Sporting Lisbon.
Arsenal are also without Christos Tzolis after letting Leandro Trossard and Gabriel Martinelli leave the club this season, so this is another opportunity for Eze or young Max Dowman to claim minutes.

