NFL Week 13 Predictions: Projections for Every Game on NFL Schedule this Week

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NFL Week 13 Predictions: Projections for Every Game on NFL Schedule this Week

NFL Week 13 Predictions: Projections for Every Game on NFL Schedule this Week — Jeff Hanisch-Imagn Images

Matt Johnson

Mon, Nov 24, 2025 ·

8 min read

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It's a special NFL schedule this week, with the Week 13 slate featuring the iconic Thanksgiving Day triple-header and the recently-introduced Black Friday game. With so many great matchups on the schedule this week, we believe this can be one of the best of the entire 2025 NFL season.

Let's dive into our NFL Week 13 predictions, delivering score projections for every game on the NFL schedule this week from Thanksgiving through Monday Night Football.

Detroit Lions 24, Green Bay Packers 17

It's an NFL classic: the Detroit Lions hosting the Green Bay Packers on Thursday Night Football. Neither NFC North contender has been quite as good as everyone expected coming into the season. At the very least, we haven't seen the dominant version of the Packers that we saw in the regular-season opening victory over Detroit. Green Bay really doesn't have the pass-catching threats who can create separation from the Lions' secondary. Meanwhile, Detroit should be able to run the football effectively enough to create third-and-shorts that prevent Micah Parsons and Co. from pinning their ears back to get after Jared Goff . In the end, we think Detroit's advantages in the run game and its superior pass-catchers dictate who comes out on top.

Kansas City Chiefs 28, Dallas Cowboys 27

We're certainly not ruling out the possibility of the Dallas Cowboys upsetting the Kansas City Chiefs on Thanksgiving. For one thing, Kansas City doesn't have much of a run game to speak of, and its offensive line could be a bit leaky against this new-look Cowboys' front seven. We can also say confidently that the Chiefs' secondary isn't well-equipped to handle both CeeDee Lamb and George Pickens , especially with Dak Prescott more than capable of outmastering Steve Spagnuolo in a chess match. In the end, it will be the weakest link for both teams (Cowboys' secondary) that allows Patrick Mahomes to get a critical win for the Chiefs.

Baltimore Ravens 31, Cincinnati Bengals 27

The nightcap for the Thanksgiving Day triple-header in Week 13 delivers the return of Joe Burrow . Unfortunately for the Cincinnati Bengals, he is still saddled by the league's worst defense and a bottom-10 offensive line. Even with Lamar Jackson not playing at 100 percent, the Baltimore Ravens will be able to run the ball at will on Cincinnati, and there'll be some deep shots available, too. We expect plenty of fireworks from both sides, but the better roster and coaching staff comes out on top despite Burrow's best efforts.

Philadelphia Eagles 20, Chicago Bears 14

Being without All-Pro right tackle Lane Johnson is a definite blow for this Philadelphia Eagles offense. Even without him, though, there'll be an opportunity on Friday night for Saquon Barkley to have success against a bottom-10 run defense. As for Caleb Williams and the Chicago Bears offense, it's just far too inconsistent to have any real success against this Eagles defense with the way they can generate pressure without blitzing and blanket top receivers in coverage. This will be a low-scoring game, but Philadelphia takes it.

San Francisco 49ers 20, Cleveland Browns 14

Points could be hard to come by in this one, even with Kyle Shanahan orchestrating an offensewith Brock Purdy , Christian McCaffrey , and George Kittle . Thanks to Myles Garrett and Co., the one thing the Cleveland Browns defense will be able to do is take advantage of the 49ers offensive line. Unfortunately for Cleveland, it doesn't have the quarterback, offensive line, or receivers to exploit this injury-depleted 49ers defense. San Francisco 's offense might not put on a clinic in Week 13, but it will get the win.

Jacksonville Jaguars 27, Tennessee Titans 17

The Jacksonville Jaguars need a strong rushing attack and an effective pass rush to win games. In Week 13, they face a Tennessee Titans team that ranks bottom 10 against the run and has allowed one of the highest sack rates in the NFL. Getting tight end Brenton Strange back should make it even easier for Travis Etienne to find running lanes on Sunday, and we expect this to be a matchup that the Jaguars win fairly comfortably.

Miami Dolphins 23, New Orleans Saints 17

We're a bit intrigued by this Week 13 matchup between the Miami Dolphins and New Orleans Saints. Both defenses have been flying under the radar for the past month, holding up particularly well versus the pass. It would also be fair to say that both of these offenses have real limitations. Miami's playmakers (De'Von Achane and Jaylen Waddle ) paired with the veteran quarterback lead us to pick the Dolphins to win, but we certainly wouldn't be surprised if rookie Tyler Shough pulls out a victory for the Saints.

New York Jets 24, Atlanta Falcons 20

The New York Jets should be favored to beat the Atlanta Falcons in Week 13, and it should be obvious. Breece Hall can have an outstanding Sunday afternoon running on a defense that is allowing nearly 140 rushing yards per game this season. Kirk Cousins is also a statue in the pocket, which will make things a lot easier for this Jets defense. The wins have been few and far between for New York, but one is coming here.

Tampa Bay Buccaneers 20, Arizona Cardinals 17

The Tampa Bay Buccaneers are getting Bucky Irving back at the right time. He'll resume his role as the lead back in this three-man group, with perfect timing for his return in Week 13 against the Arizona Cardinals. While Arizona's secondary has been better than expected this season, it's been much worse (132 rush ypg and $4.7$ ypc allowed) in the last five weeks. However, the likelihood of being without Baker Mayfield makes this a coin-flip game that Arizona could easily snag.

Los Angeles Rams 31, Carolina Panthers 13

It could be a very rough Sunday for Bryce Young . The Los Angeles Rams front seven should eat the Carolina Panthers offensive line alive, and you know defensive coordinator Chris Shula will take away the easy stuff for Young. On the other side of the ball, the Rams' receivers have a massive advantage in one-on-one matchups versus Carolina's corners, and Los Angeles should be able to run it quite easily on the Panthers.

Seattle Seahawks 24, Minnesota Vikings 14

NFL Defense Rankings — Kevin Ng-Imagn Images

The Seattle Seahawks have one of the best pass rushes in the league, and they don't have to blitz to get to the quarterback. It's a bit brutal to say, but J.J. McCarthy seems exactly like the quarterback Seahawks head coach Mike Macdonald would want his defense to face. Even if Brian Flores dials up the blitzes up the middle that force Sam Darnold into multiple interceptions versus his former team, we tend to believe the Seahawks defense alone can beat the Minnesota Vikings in Week 13.

Buffalo Bills 27, Pittsburgh Steelers 21

The Buffalo Bills offense won't lay an egg like that again, at least not anytime soon. Joe Brady needs to go back to feeding James Cook, especially in this matchup versus Pittsburgh. Besides, as recent weeks have demonstrated, you can have some success passing on the Steelers secondary. As for Pittsburgh's path to victory, it should center around Jaylen Warren going to work against a defense that has allowed a $5.3$ yards-per-carry average this season. Maybe Aaron Rodgers surprises us, but we're betting on Cook and Josh Allen carrying Buffalo to a victory.

Los Angeles Chargers 13, Las Vegas Raiders 10

It's a Week 13 matchup between the two worst offensive lines in football. Don't expect many points. What the Los Angeles Chargers do have going for them in this game against the Las Vegas Raidersis a better defense and a group of skill players that are simply more talented than the Raiders' defensive backs. Plus, even if all things were equal, Los Angeles is a far better coached team.

Denver Broncos 28, Washington Commanders 10

Defensively, the Washington Commanders hand out points like they are turkeys on Thanksgiving Day. It's the kind of opportunity Bo Nix and this Denver Broncos offense have kind of needed. We wouldn't rule out the Commanders offense getting shut out by Denver, especially if Patrick Surtain II returns in Week 13. Even if the Broncos don't get the shutout, they will beat the Commanders by multiple scores.

New England Patriots 27, New York Giants 20

Run the football and take deep shots. That's the game plan against this New York Giants defense. Drake Maye will take plenty of hits behind this New England Patriots offensive line on Monday Night Football, but he'll also get to attack New York deep. On the other side, Jaxson Dart makes his return, and it will all be on his shoulders because there won't be anywhere to run versus New England.

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