The Philadelphia Phillies are 48-22 against the Washington Nationals since June 2022, and they'll have a chance to extend that success on Wednesday. The two teams will play the finale of a two-game series at 6:45 p.m. ET at Nationals Park.
On Tuesday, Philadelphia came up short against Washington and fell 6-3.
For Washington, Daylen Lile provided the biggest spark, going a perfect 1-for-1 with a home run and three RBIs. Lile has been locked in at the plate lately, hitting .300 over his last 21 games compared to .242 in his previous 129.
The victory marked Washington's fourth in a row and improved the Nationals to 71-81. They've had to fight for that success, though, beating their opponents by an average of only 1.5 runs across that stretch. Philadelphia, meanwhile, has dropped four of its last five games and sits at 83-68.
How to Watch Philadelphia Phillies at Washington Nationals
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Date:Sept. 16, 2026
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Time:6:45 p.m. ET
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Venue:Nationals Park
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TV:NBCS-PH (road), Nationals.TV (home)
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Streaming:Stream on Fubo
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Buy tickets:Buy Phillies at Nationals tickets on Gametime
Matchup Probable Starting Pitcher Analysis
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Zack Wheeler PHI
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2026 Season Stats: 12-5 | 3.14 ERA | 1.07 WHIP | 10.8 K/9
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No decision in last start on Sept. 10 vs. HOU: 7 IP, 1 ER, 5 H
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2-3, 5.40 ERA in last nine starts; 10-2, 2.16 ERA in prior 16 games
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2.8 walks per nine innings this season; 2.0 last season
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Last start vs. WSH (Aug. 15, 2025, road): (ND) 5 IP, 2 ER, 4 H
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Jared Simpson WSH
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Jared Simpson: first start this season
Betting Philadelphia Phillies vs. Washington Nationals Betting Odds
| Moneyline |
Run Line |
Over / Under |
|---|---|---|
| PHI -197 / WSH +159 |
PHI -1.5 |
8.5 |
Betting lines as of 09/16/2026 at 4:39 a.m. ET. Odds subject to change. Bet with bet365 .
Stat Check Philadelphia Phillies Stat Check: Who's Hot, Who's Not
Who's Hot
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HOT Alec Bohm
1+ time on base in 17 straight games
Who's Not
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COLD Bryce Harper
Previous Game: 0-4
.214/.250/.357 since Sept. 4; .275/.394/.509 in prior 139 games -

COLD Bryson Stott
.139/.205/.167 since Sept. 2; .257/.333/.406 in prior 133 games
Previous Game: 0-4 -

COLD Bryan De La Cruz
Previous Game: 0-4
1-10, 2 runs in last four games; .339/.381/.500 in prior 22 games
Stat Check Washington Nationals Stat Check: Who's Hot, Who's Not
Who's Hot
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No players currently match our analysis around current trends.
Who's Not
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COLD Jacob Young
Previous Game: 0-3
0 walks in eight straight games -

COLD Dylan Crews
2-14, 1 RBIs in last four games; .224/.295/.378 in prior 93 games
Previous Game: 0-3 -

COLD Nasim Nuñez
.109/.182/.118 since July 28; .250/.333/.293 in prior 93 games
Recent Form Last 10 Games for Philadelphia Phillies (4-6)
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Sept. 15 @
San Diego Padres at Colorado Rockies MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)WSH L 3-6
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Sept. 13 @
Philadelphia Phillies at Washington Nationals MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)ATL W 9-4
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Sept. 12 @
Philadelphia Phillies at Washington Nationals MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)ATL L 2-12
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Sept. 11 @
Philadelphia Phillies at Washington Nationals MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)ATL L 5-6
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Sept. 10 vs.
Philadelphia Phillies at Washington Nationals MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)HOU L 1-2
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Sept. 9 vs.
Philadelphia Phillies at Washington Nationals MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)HOU W 11-7
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Sept. 8 vs.
Philadelphia Phillies at Washington Nationals MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)HOU L 5-6
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Sept. 7 vs.
Philadelphia Phillies at Washington Nationals MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)ATL W 1-0
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Sept. 6 vs.
Philadelphia Phillies at Washington Nationals MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)ATL L 4-5
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Sept. 5 vs.
Philadelphia Phillies at Washington Nationals MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)ATL W 4-2
Recent Form Last 10 Games for Washington Nationals (4-6)
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Sept. 15 vs.
Philadelphia Phillies at Washington Nationals MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)PHI W 6-3
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Sept. 13 vs.
Philadelphia Phillies at Washington Nationals MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)LAA W 6-5
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Sept. 12 vs.
Philadelphia Phillies at Washington Nationals MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)LAA W 6-5
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Sept. 11 vs.
Philadelphia Phillies at Washington Nationals MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)LAA W 4-3
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Sept. 9 @
San Diego Padres at Colorado Rockies MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)SD L 2-9
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Sept. 8 @
San Diego Padres at Colorado Rockies MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)SD L 4-5
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Sept. 7 @
San Diego Padres at Colorado Rockies MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)SD L 2-3
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Sept. 6 @
Philadelphia Phillies at Washington Nationals MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)LAD L 5-7
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Sept. 5 @
Philadelphia Phillies at Washington Nationals MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)LAD L 5-6
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Sept. 4 @
Philadelphia Phillies at Washington Nationals MLB Prediction, Picks & Odds for Sept. 16, 2026(athlon_sports_articles_610)LAD L 3-5
Prediction Final Score Prediction for Philadelphia Phillies @ Washington Nationals on Sept. 16, 2026
Phillies 4 – Nationals 5
Lean: Nationals
The Nationals keep this winning streak going here. It ends eventually, but not in this one.
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This story was originally published by Athlon Sports on Sep 16, 2026, where it first appeared in the MLB section. Add Athlon Sports as a Preferred Source by clicking here.

