Pirates vs Brewers Prediction, Picks & Odds for Today's MLB Game

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The Pittsburgh Pirates will attempt a series sweep of their NL Central rival, the Milwaukee Brewers , when the teams meet this afternoon.

My Pirates vs. Brewers predictions expect Pittsburgh to sweep a series in Milwaukee for the first time in a decade.

Find out why in my MLB picks for Sunday, April 26.

Who will win Pirates vs Brewers today: Pirates (+107)

Carmen Mlodzinski takes the bump for the Pittsburgh Pirates , and he’s shown improvement in his arsenal. His split-finger usage has nearly doubled from last year, a key reason he’s ranked in the 91st percentile in barrel rate.

Mlodzinski faces a Milwaukee Brewers lineup that’s posted a. 074 ISO and a 76 wRC+ over the last two weeks, ranking dead-last in both metrics.

Kyle Harrison is prime for some regression, given his ERA of 3.06 is far exceeding his 4.41 xERA. Pittsburgh’s bullpen also has the fourth-best xERA over the past two weeks and will close out the win.

COVERS INTEL:

Carmen Mlodzinski is averaging 38.4 inches of vertical drop on his split-finger fastball, an increase of 2.1 inches over last season.

Pirates vs Brewers Over/Under pick: Under 7.5 (-110)

We were unfortunate to hit the Under yesterday, with the game tied at 3-3 heading into extra innings. That said, we take that route again today.

Harrison is getting strikeouts on a consistent basis, an area where the top of Pittsburgh’s lineup has struggled at times.

The Pirates rank sixth in strikeout rate over the past two weeks,which has negated their high BABIP. They’re also right at 100 in wRC+ in that span.

The Brewers have scored just nine runs in their last four games, and their struggles at the plate will help keep this score low.

[WRITER NAME]'s 2026 Transparency Record

• ML/RL bets:1-4, -3.50 units

• Over/Under bets:4-1, +2.91 units

Pirates vs Brewers odds

• Moneyline: Pirates +108 | Brewers -113

• Run line: Pirates +1.5 (-194) | Brewers -1.5 (+186)

• Over/Under: Over 7.5 (-104) | Under 7.5 (+100)

Pirates vs Brewers trend

The Pittsburgh Pirates have hit the run line in 15 of their last 22 games (+9.65 Units / 34% ROI). Find more MLB betting trends for Pirates vs. Brewers.

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