Cheap flights from Chicago to Santa Cruz de la Sierra

Flights overview

Useful information for finding cheap flights from Chicago to Santa Cruz de la Sierra and booking your next trip
Cheapest round-trip flights $700
Avianca 1 stop 27 hr Sun, May 3 — Sat, May 16
The cheapest round-trip flight from Chicago to Santa Cruz de la Sierra is currently $700
Cheapest one-way flight $351
COPA 1 stop 12 hr Sun, May 3
The cheapest one-way flight from Chicago to Santa Cruz de la Sierra is currently $351
Last-minute weekend getaway $806
Avianca, United 2 stops 17 hr Thu, May 7 — Sun, May 10
The cheapest last-minute weekend getaway from Chicago to Santa Cruz de la Sierra is currently $806
Cheapest business class flights $1,185
COPA, United 2 stops 17 hr Sun, May 3 — Tue, May 19
The cheapest business class round-trip flight from Chicago to Santa Cruz de la Sierra is currently $1,185
Fastest flight 11 hr 10 min The fastest flight with stops from Chicago to Santa Cruz de la Sierra takes 11 hr 10 min
Nonstop flights None There are no direct flights on this route.

When is the cheapest time to fly?

The cheapest month to fly from Chicago to Santa Cruz de la Sierra is typically October. The most expensive month to fly is typically July.
October
Cheapest
Typical prices: $415–590
July
Most expensive
Typical prices: $790–990

Popular airlines from Chicago to Santa Cruz de la Sierra

  • COPA
    from $760
    Typical price: $580–1,450
    20 weekly connecting flights
    ORD - VVI Every day
  • Avianca
    from $700
    Typical price: $700–1,200
    7 weekly connecting flights
    ORD - VVI Every day

Popular airports near Chicago

  • Chicago O'Hare International Airport (ORD)
    Chicago United States 26 min 16 mi
  • Chicago Midway International Airport (MDW)
    Chicago United States 25 min 9 mi
  • Milwaukee Mitchell International Airport (MKE)
    Milwaukee United States 1 hr 23 min 75 mi
  • Indianapolis International Airport (IND)
    Indianapolis United States 2 hr 58 min 165 mi

Popular airports near Santa Cruz de la Sierra

  • Viru Viru International Airport (VVI) (VVI)
    Santa Cruz de la Sierra Bolivia 29 min 11 mi

Frequently asked questions about flying from Chicago to Santa Cruz de la Sierra

The cheapest flights from Chicago to Santa Cruz de la Sierra are usually in October. Typical ticket prices in October range from $415 to $590.
The cheapest round-trip flight from Chicago to Santa Cruz de la Sierra recently found on Google Flights was with Avianca from $700. The cheapest one-way flight was with COPA from $351.

Some of the cheapest round-trip deals we found with different airlines:
  • The cheapest COPA flight from Chicago to Santa Cruz de la Sierra is $760, flying from May 3 to May 18.
  • The cheapest Avianca flight from Chicago to Santa Cruz de la Sierra is $700, flying from May 3 to May 16.
The cheapest round-trip flight from Chicago to Santa Cruz de la Sierra starts at $700 from Sun, May 3 to Sat, May 16. The cheapest one-way flight starts at $351 and departs on Sun, May 3.
11 hr 10 min is the shortest flight time from Chicago to Santa Cruz de la Sierra.
Santa Cruz de la Sierra is an all-year destination, with the most popular months being Dec–Jan. The tropical weather is warm-to-hot year-round, with the heaviest rainfall in Dec–Jan. Key annual events include Carnaval (Feb/Mar, dates vary), the Festival de Música Misiones de Chiquitos (Apr–May), celebrating American Renaissance and baroque music, and the city’s independence day (Sep 24).
It's easy to use Google Flights to find the cheapest days to fly from Chicago to Santa Cruz de la Sierra.
Just click the Departure label near the top of the page to open the calendar. Choose a start date and a return date to see how the round-trip fare changes on those specific days.
Adjust the trip type to see one-way fares. The cheapest available flights are highlighted and easy to spot. Once you settle on dates, click the Search button to see flight options and book the deal.

You can also turn on price tracking to get alerts if the price changes for a route or flight.
What counts as the best airline for your flights from Chicago to Santa Cruz de la Sierra really depends on your individual needs. You may have a favorite carrier or a loyalty program you like, but price, convenience, and airports served also come into play. Flexibility and booking terms – Can you change flights if you want to stay longer or get a refund if you have to postpone your trip? – are also factors that help determine which airline is best to fly from Chicago to Santa Cruz de la Sierra.

In terms of flights, COPA is the most popular. COPA offers 20 connecting flights per week. COPA flies from Chicago O'Hare International Airport (ORD) to Viru Viru International Airport (VVI) (VVI) .

Another popular airline flying from Chicago to Santa Cruz de la Sierra is:
  • Avianca offers 7 connecting flights per week. Avianca flies from Chicago O'Hare International Airport (ORD) to Viru Viru International Airport (VVI) (VVI) .
The number of connecting flights refers to distinct flights with at least one stop between Chicago and Santa Cruz de la Sierra.
The cheapest round-trip flight from Chicago to Santa Cruz de la Sierra recently found on Google Flights was with Avianca from $700. The cheapest one-way flight was with COPA from $351.

Some of the cheapest round-trip deals we found with different airlines:
  • The cheapest COPA flight from Chicago to Santa Cruz de la Sierra is $760, flying from May 3 to May 18.
  • The cheapest Avianca flight from Chicago to Santa Cruz de la Sierra is $700, flying from May 3 to May 16.
No airline flies direct from Chicago to Santa Cruz de la Sierra.
  • There are 20 COPA connecting flights from Chicago to Santa Cruz de la Sierra per week. Flights are available every day.
  • There are 7 Avianca connecting flights from Chicago to Santa Cruz de la Sierra per week. Flights are available every day.
Use the Stops filter while searching for flights, to see only nonstop options in your results.
The cheapest last-minute deal between Chicago and Santa Cruz de la Sierra at price $806 is offered by Avianca, United from Thu, May 7 to Sun, May 10.
No airline flies direct from Chicago to Santa Cruz de la Sierra.
  • There are 20 COPA connecting flights from Chicago to Santa Cruz de la Sierra per week. Flights are available every day.
  • There are 7 Avianca connecting flights from Chicago to Santa Cruz de la Sierra per week. Flights are available every day.
Use the Stops filter while searching for flights, to see only nonstop options in your results.
There are no direct flights from Chicago to Santa Cruz de la Sierra.
It's easy to find nonstop flights with Google Flights! Once you've searched for flights from Chicago to Santa Cruz de la Sierra, just select the nonstop flights only option in the 'Stops’ filter in the search form and view all available direct flights and their prices.
The cheapest business class round-trip flights between Chicago and Santa Cruz de la Sierra start at $1,185 from Sun, May 3 to Tue, May 19 with COPA, United.
The cheapest economy class round-trip flights between Chicago and Santa Cruz de la Sierra start at $700 from Sun, May 3 to Sat, May 16.
To book business class trips from Chicago to Santa Cruz de la Sierra, look for the default Economy selection at the top, and change it to your desired cabin class such as Premium Economy, Business Class, or First Class. You can then select your departure and arrival dates, consider available options, and book your business travel.

You can also adjust the trip type to view one-way fares.
The best last-minute getaway deal for the next weekend between Chicago and Santa Cruz de la Sierra starts at $806 from Thu, May 7 to Sun, May 10 with Avianca, United.
The cheapest last-minute deal between Chicago and Santa Cruz de la Sierra at price $806 is offered by Avianca, United from Thu, May 7 to Sun, May 10.
To find last-minute flight deals from Chicago to Santa Cruz de la Sierra, start by entering the city names, select the desired departure and return dates, and hit the Search button to view flight options.

You can check for last-minute flights for the same day or adjust the trip type to see one-way fares.

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