Last Saturday I attended the seminar "Open Academy" held by Quintiles Transinternational Japan. The subject of seminar was "What should do MRs in the future?", that was so informative for MRs who are going to survive through tougher becoming environments. I steadly realized we MRs not only can contribute clinical activities but also must do as such. I am so grateful for excellent talk by Sato-san, CEO of Pharma Business Academy, and Kokubo-san, CEO of Pharma Wisdom Consortium, and excellent coordiation by Numata-san, editor in chief of Montly Mix Magazine.