
| Player | Date | P | Comment |
|---|---|---|---|
| 11/4/2026 | D | Activated (The Buffalo Sabres activated D Conor Timmins from injured reserve.) | |
| 11/1/2026 | D | Sent to minors (The Buffalo Sabres assigned D Dennis Gilbert to the minors.) | |
| 10/30/2026 | RW | Placed on Injured Reserve (The Buffalo Sabres placed F Justin Danforth on injured reserve.) | |
| 10/29/2026 | C | Activated (The Buffalo Sabres activated F Sam Carrick from injured reserve.) | |
| 10/21/2026 | C | Placed on Injured Reserve (The Buffalo Sabres placed F Sam Carrick on injured reserve.) | |
| 10/21/2026 | LW | Activated (The Buffalo Sabres activated F Jason Zucker form injured reserve.) | |
| 10/17/2026 | G | Sent to minors (The Buffalo Sabres assigned G Topias Leinonen to the minors.) | |
| 10/13/2026 | D | Placed on Injured Reserve (The Buffalo Sabres placed D Matt Grzelcyk on injured reserve.) | |
| 10/13/2026 | D | Called up from minors (The Buffalo Sabres recalled D Dennis Gilbert from the minors.) | |
| 10/12/2026 | D | Traded (The Buffalo Sabres traded D Ryan Johnson to the Pittsburgh Penguins.) To Pittsburgh | |
| 10/12/2026 | D | Traded (The Pittsburgh Penguins traded D Caleb Jones to the Buffalo Sabres.) From Pittsburgh | |
| 10/12/2026 | D | Traded (The Pittsburgh Penguins traded D Daniel Laatsch to the Buffalo Sabres.) From Pittsburgh | |
| 10/2/2026 | D | Sent to minors (The Buffalo Sabres assigned D Dennis Gilbert to the minors.) | |
| 10/2/2026 | D | Activated (The Buffalo Sabres activated D Olen Zellweger from injured reserve.) | |
| 10/1/2026 | G | Placed on Injured Reserve (The Buffalo Sabres placed G Alex Lyon on injured reserve.) | |
| 10/1/2026 | D | Placed on Injured Reserve (The Buffalo Sabres placed D Olen Zellweger on injured reserve.) | |
| 10/1/2026 | D | Activated (The Buffalo Sabres activated D Mattias Samuelsson from Injured Reserve.) | |
| 10/1/2026 | D | Called up from minors (The Buffalo Sabres recalled D Dennis Gilbert from the minors.) | |
| 9/30/2026 | RW | Sent to minors (The Buffalo Sabres assigned F Caden Dabrowski to the minors.) | |
| 9/30/2026 | RW | Sent to minors (The Buffalo Sabres assigned F Brayden Holberton to the minors.) | |
| 9/30/2026 | C | Sent to minors (The Buffalo Sabres assigned F Sawyer Mayes to the minors.) | |
| 9/30/2026 | LW | Placed on Injured Reserve (The Buffalo Sabres placed F Jason Zucker on injured reserve.) | |
| 9/30/2026 | RW | Sent to minors (The Buffalo Sabres assigned F Cohen Bidgood to the minors.) | |
| 9/30/2026 | D | Sent to minors (The Buffalo Sabres assigned D Jack Rathbone to the minors.) | |
| 9/30/2026 | D | Sent to minors (The Buffalo Sabres assigned D Kristopher Richards to the minors.) | |
| 9/30/2026 | RW | Activated (The Buffalo Sabres activated F Justin Danforth.) | |
| 9/30/2026 | LW | Sent to minors (The Buffalo Sabres assigned F Jean-Christoph Lemieux to the minors.) | |
| 9/29/2026 | LW | Waived (The Buffalo Sabres waived F Conor Sheary.) | |
| 9/29/2026 | LW | Placed on Injured Reserve (The Buffalo Sabres placed F Conor Sheary on injured reserve.) | |
| 9/28/2026 | D | Placed on Injured Reserve (The Buffalo Sabres placed D Jack Rathbone on injured reserve.) | |
| 9/28/2026 | G | Placed on Injured Reserve (The Buffalo Sabres placed G Topias Leinonen on injured reserve.) | |
| 9/28/2026 | D | Placed on Injured Reserve (The Buffalo Sabres placed D Mattias Samuelsson on injured reserve.) | |
| 9/28/2026 | D | Placed on Injured Reserve (The Buffalo Sabres placed D Conor Timmins on injured reserve.) | |
| 9/25/2026 | D | Sent to minors (The Buffalo Sabres assigned D Ryan Johnson to the minors.) | |
| 9/25/2026 | C | Sent to minors (The Buffalo Sabres assigned F Graham Slaggert to the minors.) | |
| 9/25/2026 | D | Sent to minors (The Buffalo Sabres assigned D Vsevolod Komarov to the minors.) | |
| 9/25/2026 | D | Sent to minors (The Buffalo Sabres assigned D Radim Mrtka to the minors.) | |
| 9/25/2026 | RW | Sent to minors (The Buffalo Sabres assigned F Jake Richard to the minors.) | |
| 9/25/2026 | RW | Sent to minors (The Buffalo Sabres assigned F Jason Polin to the minors.) | |
| 9/25/2026 | D | Sent to minors (The Buffalo Sabres assigned D Dennis Gilbert to the minors.) | |
| 9/25/2026 | RW | Sent to minors (The Buffalo Sabres assigned F Zac Funk to the minors.) | |
| 9/25/2026 | D | Sent to minors (The Buffalo Sabres assigned D Maxim Strbak to the minors.) | |
| 9/25/2026 | C | Sent to minors (The Buffalo Sabres assigned F Trevor Kuntar to the minors.) | |
| 9/25/2026 | D | Sent to minors (The Buffalo Sabres assigned D Noah Laaouan to the minors.) | |
| 9/25/2026 | G | Sent to minors (The Buffalo Sabres assigned G Talyn Boyko to the minors.) | |
| 9/25/2026 | C | Sent to minors (The Buffalo Sabres assigned F Matteo Costantini to the minors.) | |
| 9/25/2026 | LW | Sent to minors (The Buffalo Sabres assigned F Mason Geertsen to the minors.) | |
| 9/25/2026 | C | Sent to minors (The Buffalo Sabres assigned F Riley Fiddler-Schultz to the minors.) | |
| 9/25/2026 | RW | Sent to minors (The Buffalo Sabres assigned F Carson Meyer to the minors.) | |
| 9/25/2026 | LW | Sent to minors (The Buffalo Sabres assigned F Aidan McDonough to the minors.) | |
| 9/25/2026 | G | Sent to minors (The Buffalo Sabres assigned G Matt Villalta to the minors.) | |
| 9/25/2026 | G | Sent to minors (The Buffalo Sabres assigned G Scott Ratzlaff to the minors.) | |
| 9/25/2026 | D | Sent to minors (The Buffalo Sabres assigned D Gavin McCarthy to the minors.) | |
| 9/25/2026 | LW | Sent to minors (The Buffalo Sabres assigned F Brendan Warren to the minors.) | |
| 9/25/2026 | C | Sent to minors (The Buffalo Sabres assigned F Redmond Savage to the minors.) | |
| 9/25/2026 | C | Sent to minors (The Buffalo Sabres assigned F Thomas Bordeleau to the minors.) | |
| 9/25/2026 | RW | Sent to minors (The Buffalo Sabres assigned F Liam Valente to the minors.) | |
| 9/25/2026 | C | Sent to minors (The Buffalo Sabres assigned F Matthew Peca to the minors.) | |
| 9/25/2026 | D | Signed (The Buffalo Sabres signed D Matt Grzelcyk.) | |
| 9/21/2026 | RW | Signed (The Buffalo Sabres signed F Cohen Bidgood.) | |
| 9/21/2026 | LW | Signed (The Buffalo Sabres signed F Jean-Christoph Lemieux.) | |
| 9/21/2026 | RW | Signed (The Buffalo Sabres signed F Brayden Holberton.) | |
| 9/21/2026 | RW | Signed (The Buffalo Sabres signed F Caden Dabrowski.) | |
| 9/21/2026 | D | Signed (The Buffalo Sabres signed D Kristopher Richards.) | |
| 9/21/2026 | C | Signed (The Buffalo Sabres signed F Sawyer Mayes.) | |
| 9/17/2026 | C | Activated (The Buffalo Sabres activated F Jiri Kulich from injured reserve.) | |
| 9/15/2026 | C | Sent to minors (The Buffalo Sabres assigned F Doman Szongoth to the minors.) | |
| 9/15/2026 | RW | Sent to minors (The Buffalo Sabres assigned F Dylan Dumont to the minors.) | |
| 8/17/2026 | RW | Traded (The Buffalo Sabres traded F Stiven Sardarian to the Carolina Hurricanes.) To Carolina | |
| 8/17/2026 | D | Sent to minors (The Buffalo Sabres sent D Radim Mrtka to the minors.) | |
| 7/13/2026 | RW | Traded (The Washington Capitals traded F Zac Funk to the Buffalo Sabres.) From Washington | |
| 7/13/2026 | LW | Traded (The Buffalo Sabres traded F Tyler Kopff to the Washington Capitals.) To Washington | |
| 7/4/2026 | G | Signed (The Buffalo Sabres signed G Matt Villalta to a two-way contract.) | |
| 7/2/2026 | LW | Signed (The Buffalo Sabres signed F Aidan McDonough to a two-way contract.) | |
| 7/2/2026 | LW | Became Unrestricted Free Agent (F Jagger Joshua elected free agency.) | |
| 7/1/2026 | LW | Signed (The Buffalo Sabres signed F Conor Sheary.) | |
| 7/1/2026 | RW | Signed (The Buffalo Sabres signed F Jason Polin.) | |
| 7/1/2026 | G | Traded (The Buffalo Sabres traded G Devon Levi to the Edmonton Oilers.) To Edmonton | |
| 7/1/2026 | C | Signed (The Buffalo Sabres signed F Trevor Kuntar.) | |
| 7/1/2026 | D | Became Unrestricted Free Agent (D Zachary Jones elected free agency) | |
| 7/1/2026 | D | Signed (The Buffalo Sabres signed D Dennis Gilbert.) | |
| 6/30/2026 | D | Became Unrestricted Free Agent (D Isaac Belliveau elected free agency.) | |
| 6/30/2026 | D | Became Unrestricted Free Agent (D Nikita Novikov elected free agency.) | |
| 6/30/2026 | D | Became Unrestricted Free Agent (D Zachary Jones elected free agency) | |
| 6/30/2026 | LW | Became Unrestricted Free Agent (F Jagger Joshua elected free agency.) | |
| 6/30/2026 | D | Became Unrestricted Free Agent (D Gavin Bayreuther elected free agency.) | |
| 6/30/2026 | C | Became Unrestricted Free Agent (The Buffalo Sabres F Josh Dunne elected free agency.) | |
| 6/29/2026 | C | Became Unrestricted Free Agent (The Buffalo Sabres F Jake Leschyshyn elected free agency.) | |
| 6/29/2026 | D | Became Unrestricted Free Agent (D Logan Stanley elected free agency.) | |
| 6/29/2026 | D | Became Unrestricted Free Agent (D Luke Schenn elected free agency.) | |
| 6/29/2026 | LW | Became Unrestricted Free Agent (F Tanner Pearson elected free agency.) | |
| 6/27/2026 | RW | Drafted (The Buffalo Sabres drafted F Dylan Dumont) | |
| 6/27/2026 | C | Drafted (The Buffalo Sabres drafted F Doman Szongoth.) | |
| 6/27/2026 | C | Drafted (The Buffalo Sabres drafted F Olivers Murnieks) | |
| 6/26/2026 | C | Drafted (The Buffalo Sabres drafted F Ilia Morozov.) | |
| 6/26/2026 | D | Drafted (The Buffalo Sabres drafted D Daxon Rudolph.) | |
| 6/26/2026 | C | Traded (The Buffalo Sabres traded F Anton Wahlberg to the Anaheim Ducks.) To Anaheim | |
| 6/26/2026 | D | Traded (The Anaheim Ducks traded D Olen Zellweger to the Buffalo Sabres.) From Anaheim | |
| 6/24/2026 | C | Traded (The Washington Capitals traded F David Kampf to the Buffalo Sabres.) From Washington | |
| 6/24/2026 | RW | Traded (The Buffalo Sabres traded F Alex Tuch to the Washington Capitals.) To Washington | |
| 6/24/2026 | D | Traded (The Buffalo Sabres traded D Bowen Byram to the Chicago Blackhawks.) To Chicago | |
| 6/24/2026 | D | Traded (The Chicago Blackhawks traded D Louis Crevier to the Buffalo Sabres.) From Chicago | |
| 6/24/2026 | LW | Traded (The Buffalo Sabres traded F Jordan Greenway to the Chicago Blackhawks.) To Chicago | |
| 6/17/2026 | D | Traded (The Buffalo Sabres traded D Michael Kesselring to the San Jose Sharks.) To San Jose |