
| Player | Pos | Status | Date |
|---|---|---|---|
| SP | day-to-day (Elbow) | 9/4 | |
| LF | day-to-day (Shoulder) | 9/4 | |
| 1B | 10-day IL (The San Diego Padres placed INF Gavin Sheets on the 10-day injured list with left foot sprain.) | 8/30 | |
| LF | 60-day IL (The San Diego Padres transferred OF Luis Rengifo from the 10-day injured list to the 60-day injured list with a right knee sprain.) | 8/29 | |
| RP | 15-day IL (The San Diego Padres placed RHP Jeremiah Estrada on the 15-day injured list with right shoulder impingement.) | 8/25 | |
| DH | 10-day IL (The San Diego Padres placed DH Miguel Andujar on the 10-day injured list due to fractured right wrist.) | 7/20 | |
| RP | 60-day IL (The San Diego Padres placed RHP Jason Adam on the 60-day injured list with a right shoulder strain.) | 6/30 | |
| SP | 60-day IL (The San Diego Padres transferred RHP Lucas Giolito to the 60-day injured list with right elbow inflammation.) | 6/23 | |
| LF | 60-day IL (The San Diego Padres placed OF Ramón Laureano on the 60-day injured list.) | 5/31 | |
| SP | 60-day IL (The San Diego Padres transferred RHP Nick Pivetta from the 15-day injured list to the 60-day injured list with a right elbow inflammation.) | 4/13 | |
| SP | 60-day IL (The San Diego Padres transferred RHP Joe Musgrove to the 60-day injured list due to his elbow surgery.) | 3/25 | |
| RP | 60-day IL (The San Diego Padres transferred RHP Bryan Hoeing from the 15-day injured list to the 60-day injured list due to a right elbow surgery.) | 3/25 |