
| Player | Pos | Status | Date |
|---|---|---|---|
| RP | 15-day IL (The San Francisco Giants placed LHP Sam Hentges on the 15-day injured list with left forearm strain.) | 8/27 | |
| SP | 60-day IL (The San Francisco Giants transferred LHP Carson Whisenhunt from the 15-day injured list to the 60-day injured list with elbow sprain.) | 8/26 | |
| SP | 60-day IL (The San Francisco Giants transferred RHP Adrian Houser to the 60-day injured list due to a right forearm strain.) | 8/25 | |
| RP | 15-day IL (The San Francisco Giants placed RHP JT Brubaker on the 15-day injured list due to bruised ribs.) | 8/24 | |
| LF | 10-day IL (The San Francisco Giants placed OF Victor Bericoto on the 10-day injured list due to a knee injury.) | 8/23 | |
| SS | 10-day IL (The San Francisco Giants placed INF Willy Adames on the 10-day injured list due to an elbow injury.) | 8/23 | |
| RP | 60-day IL (The San Francisco Giants placed RHP Keaton Winn on the 60-day injured list with right elbow neuritis.) | 8/19 | |
| C | 60-day IL (The San Francisco Giants transferred C Daniel Susac to the 60-day injured list.) | 8/10 | |
| C | 60-day IL (The San Francisco Giants placed C Jesus Rodriguez on the 60-day injured list with a right elbow neuritis.) | 8/1 | |
| LF | 60-day IL (The San Francisco Giants transferred OF Casey Schmitt from the 10-day injured list to the 60-day injured list due to left knee meniscus tear.) | 7/28 | |
| SP | 60-day IL (The San Francisco Giants transferred RHP Trevor McDonald from the 15-day injured list to the 60-day injured list with a right elbow strain.) | 7/21 | |
| RP | 60-day IL (The San Francisco Giants transferred LHP Matt Gage from the 15-day injured list to the 60-day injured list due to left elbow strain.) | 7/4 | |
| 3B | 60-day IL (The San Francisco Giants transferred INF Matt Chapman to the 60-day injured list due to abdominal strain.) | 6/30 | |
| 2B | 10-day IL (The San Francisco Giants placed INF Marcelo Mayer on the 10-day injured list with a stress reaction on his left forearm.) | 6/26 | |
| RP | 60-day IL (The San Francisco Giants placed RHP Joel Peguero on the 60-day injured list with a left hamstring strain.) | 6/1 | |
| CF | 60-day IL (The San Francisco Giants transferred OF Harrison Bader to the 60-day injured list.) | 5/30 | |
| RP | 60-day IL (The San Francisco Giants transferred RHP José Buttó to the the 60-day injured list with right arm fatigue.) | 4/2 | |
| SP | 60-day IL (The San Francisco Giants placed RHP Hayden Birdsong on the 60-day injured list as he is scheduled to undergo Tommy John surgery.) | 3/21 | |
| RP | 60-day IL (The San Francisco Giants placed RHP Rowan Wick on the 60-day injured list as he recovers from Tommy John surgery.) | 2/15 | |
| RP | 60-day IL (The San Francisco Giants placed RHP Randy Rodríguez on the 60-day injured list due to a right elbow sprain.) | 2/10 |