Keyjuan Brown ran for a career-high 163 yards and a pair of long touchdowns on 10 carries to guide No. 23 Louisville to a 41-31 victory over 16th-ranked SMU on Saturday. The preseason media picks to finish second (SMU) and third (Louisville) in the Atlantic Coast Conference put on a back-and-forth affair, trading the lead eight times before the Cardinals sealed it on Isaac Brown’s 27-yard touchdown with 5:32 remaining to finish the scoring. The Cardinals (2-1, 1-0 ACC) then stripped SMU quarterback Kevin Jennings of the ball just before the goal line on the Mustangs’ ensuing drive, turning what would have been a 19-yard touchdown into a touchback as the ball rolled out of the end zone with 2:43 remaining.