
| Player | Pos | Status | Date |
|---|---|---|---|
| C | Out (Kulich has been placed in concussion protocol, per Rachel Lenzi of The Buffalo News on Monday (Oct. 26).) | 10/23 | |
| C | Injured Reserve (The Buffalo Sabres placed F Sam Carrick on injured reserve on Wednesday (Oct. 21).) | 10/20 | |
| RW | Day-to-Day (Danforth did not play in Tuesday's (Oct. 27) game against the Sharks.) | 10/19 | |
| D | Injured Reserve (The Buffalo Sabres placed D Matt Grzelcyk on injured reserve on Tuesday (Oct. 13).) | 10/13 | |
| G | Injured Reserve (The Buffalo Sabres said on Thursday's (Oct. 15) that Lyon had a setback in his recovery and is without a timeline to return.) | 9/29 | |
| D | Injured Reserve (The Buffalo Sabres placed D Conor Timmins on injured reserve and does not have a timeline for his return yet, according to Heather Engel of NHL.com.) | 9/28 | |
| D | Injured Reserve (The Buffalo Sabres placed D Jack Rathbone on injured reserve non-roster list on Monday (Sep. 28).) | 9/28 |