San Francisco 49ers May Be Without DE Nick Bosa for Multiple Weeks Ross Johnston reacts to the latest injury report with 49ers DE Nick Bosa. 1:53 Now Playing Paused Ad Playing 49ers' Nick Bosa Injury Update Raises BIG Concerns 2:22 Now Playing Paused Ad Playing 49ers Talk: Nick Bosa's calf injury adds to growing IR list ahead of Week 3 2:40 Now Playing Paused Ad Playing San Francisco 49ers DE Nick Bosa is a Go for Week 1 2:14 Now Playing Paused Ad Playing San Francisco 49ers DE Nick Bosa is a Go for Week 1 2:14 Now Playing Paused Ad Playing Bosa's absence from practice 'not a good sign' 1:53 Now Playing Paused Ad Playing What Nick Bosa's injury means for 49ers' depleted defensive line 7:20 Now Playing Paused Ad Playing Inside Nick Bosa’s Delayed Return: Why the 49ers Pumped the Brakes Ahead of the Bye 2:09 Now Playing Paused Ad Playing 49ers DE Nick Bosa is Not at Monday's Practice 1:41 Now Playing Paused Ad Playing 49ers Talk: Nick Bosa experiencing tendinitis in surgically repaired knee 1:55 Now Playing Paused Ad Playing 49ers Talk: Assessing Nick Bosa's availability for international game vs. Rams 1:59 Now Playing Paused Ad Playing San Francisco 49ers May Be Without DE Nick Bosa for Multiple Weeks AtoZ Sports Fri, Sep 25, 2026 Ross Johnston reacts to the latest injury report with 49ers DE Nick Bosa . San Francisco 49ers May Be Without DE Nick Bosa for Multiple Weeks Ross Johnston reacts to the latest injury report with 49ers DE Nick Bosa. 1:53 Now Playing Paused Ad Playing 49ers' Nick Bosa Injury Update Raises BIG Concerns 2:22 Now Playing Paused Ad Playing 49ers Talk: Nick Bosa's calf injury adds to growing IR list ahead of Week 3 2:40 Now Playing Paused Ad Playing San Francisco 49ers DE Nick Bosa is a Go for Week 1 2:14 Now Playing Paused Ad Playing San Francisco 49ers DE Nick Bosa is a Go for Week 1 2:14 Now Playing Paused Ad Playing Bosa's absence from practice 'not a good sign' 1:53 Now Playing Paused Ad Playing What Nick Bosa's injury means for 49ers' depleted defensive line 7:20 Now Playing Paused Ad Playing Inside Nick Bosa’s Delayed Return: Why the 49ers Pumped the Brakes Ahead of the Bye 2:09 Now Playing Paused Ad Playing 49ers DE Nick Bosa is Not at Monday's Practice 1:41 Now Playing Paused Ad Playing 49ers Talk: Nick Bosa experiencing tendinitis in surgically repaired knee 1:55 Now Playing Paused Ad Playing 49ers Talk: Assessing Nick Bosa's availability for international game vs. Rams 1:59 Now Playing Paused Ad Playing