Detroit Lions Week 2 Preview Against Buffalo Bills Examining Detroit Lions keys to victory in Week 2 NFL contest against Buffalo Bills. 2:14 Now Playing Paused Ad Playing Week 2 NFL Preview: Lions vs. Bills High-Octane Matchup 3:37 Now Playing Paused Ad Playing Keys to Week 2 Victory For Detroit Lions Against Buffalo Bills 1:44 Now Playing Paused Ad Playing Detroit Lions Are Betting Underdogs To Buffalo Bills Week 2 1:31 Now Playing Paused Ad Playing Lions vs. Bills could be ‘fireworks’ in Week 2 8:13 Now Playing Paused Ad Playing Bills-Lions preview: Will Josh Allen, Buffalo roll in new stadium debut? 2:37 Now Playing Paused Ad Playing Thursday Night Preview: Bills vs. Lions - Who Will Dominate? 5:05 Now Playing Paused Ad Playing The Lions vs Bills Game Will Come Down To THIS... 9:36 Now Playing Paused Ad Playing Ride with Bills as 3.5-point favorites vs. Lions 2:15 Now Playing Paused Ad Playing Lions will have a 'hard time' with Allen in Week 2 2:57 Now Playing Paused Ad Playing Expect high-scoring affair between Bills and Lions 10:56 Now Playing Paused Ad Playing Detroit Lions Week 2 Preview Against Buffalo Bills Detroit Lions On SI Thu, Sep 17, 2026 Examining Detroit Lions keys to victory in Week 2 NFL contest against Buffalo Bills . Detroit Lions Week 2 Preview Against Buffalo Bills Examining Detroit Lions keys to victory in Week 2 NFL contest against Buffalo Bills. 2:14 Now Playing Paused Ad Playing Week 2 NFL Preview: Lions vs. Bills High-Octane Matchup 3:37 Now Playing Paused Ad Playing Keys to Week 2 Victory For Detroit Lions Against Buffalo Bills 1:44 Now Playing Paused Ad Playing Detroit Lions Are Betting Underdogs To Buffalo Bills Week 2 1:31 Now Playing Paused Ad Playing Lions vs. Bills could be ‘fireworks’ in Week 2 8:13 Now Playing Paused Ad Playing Bills-Lions preview: Will Josh Allen, Buffalo roll in new stadium debut? 2:37 Now Playing Paused Ad Playing Thursday Night Preview: Bills vs. Lions - Who Will Dominate? 5:05 Now Playing Paused Ad Playing The Lions vs Bills Game Will Come Down To THIS... 9:36 Now Playing Paused Ad Playing Ride with Bills as 3.5-point favorites vs. Lions 2:15 Now Playing Paused Ad Playing Lions will have a 'hard time' with Allen in Week 2 2:57 Now Playing Paused Ad Playing Expect high-scoring affair between Bills and Lions 10:56 Now Playing Paused Ad Playing