
| Player | Date | P | Comment |
|---|---|---|---|
| 11/3/2026 | SP | Traded (The St. Louis Cardinals traded SP Juan García to the Boston Red Sox.) To Boston | |
| 11/3/2026 | SP | Traded (The Boston Red Sox traded SP Eduardo Rivera to the St. Louis Cardinals.) From Boston | |
| 11/2/2026 | RP | Declared Free Agency (St. Louis Cardinals RP Ryne Stanek declared free agency.) | |
| 11/2/2026 | SP | Claimed on Unconditional Release Waivers (The Baltimore Orioles claimed SP Chase Hampton off waivers from the St. Louis Cardinals.) To Baltimore | |
| 11/2/2026 | SP | Designated for Assignment (The St. Louis Cardinals designated SP Chase Hampton for assignment.) | |
| 10/1/2026 | SP | Traded (The Arizona Diamondbacks traded SP Brian Curley to the St. Louis Cardinals.) From Arizona | |
| 9/30/2026 | RP | Declared Free Agency (St. Louis Cardinals RP Jared Shuster declared free agency.) | |
| 9/29/2026 | SP | Activated (The St. Louis Cardinals activated RHP Tekoah Roby.) | |
| 9/29/2026 | RF | Activated (The St. Louis Cardinals activated RF Everson Pereira from the 10-day injured list.) | |
| 9/29/2026 | LF | Activated (The St. Louis Cardinals activated LF Joshua Báez from the 10-day injured list.) | |
| 9/29/2026 | RP | Activated (The St. Louis Cardinals activated Matt Svanson.) | |
| 9/29/2026 | RP | Activated (The St. Louis Cardinals activated RHP Ryan Fernandez.) | |
| 9/29/2026 | C | Activated (The St. Louis Cardinals activated C Jimmy Crooks.) | |
| 9/29/2026 | 3B | Activated (The St. Louis Cardinals activated 3B Blaze Jordan from the 10-day injured list.) | |
| 9/29/2026 | SP | Activated (The St. Louis Cardinals activated SP Hunter Dobbins from the 15-day injured list.) | |
| 9/29/2026 | SP | Activated (The St. Louis Cardinals activated SP Max Rajcic from the 60-day injured list.) | |
| 9/29/2026 | SP | Activated (The St. Louis Cardinals activated LHP Cooper Hjerpe.) | |
| 9/29/2026 | SP | Activated (The St. Louis Cardinals activated RHP Richard Fitts.) | |
| 9/29/2026 | SP | Activated (The St. Louis Cardinals activated RHP Chase Hampton) | |
| 9/28/2026 | SP | Claimed on Unconditional Release Waivers (The St. Louis Cardinals claimed SP Chase Hampton off waivers from the Washington Nationals.) From Washington | |
| 9/25/2026 | SP | Recalled From Minors Rehab (The St. Louis Cardinals recalled SP Hancel Rincon from the minors.) | |
| 9/24/2026 | SP | Sent to Minors (The St. Louis Cardinals optioned SP Cooper Hjerpe to the minors.) | |
| 9/19/2026 | RP | Declared Free Agency (St. Louis Cardinals RP Peter Strzelecki declared free agency.) | |
| 9/18/2026 | LF | Placed on 10-Day IL (The St. Louis Cardinals placed LF Joshua Báez on the 10-day injured list.) | |
| 9/18/2026 | 3B | Recalled From Minors Rehab (The St. Louis Cardinals recalled 3B Cesar Prieto from the minors.) | |
| 9/16/2026 | 2B | Activated (The St. Louis Cardinals activated 2B JJ Wetherholt from the 10-day injured list.) | |
| 9/16/2026 | 3B | Designated for Assignment (The St. Louis Cardinals designated 3B Ramón Urías for assignment.) | |
| 9/16/2026 | RP | Designated for Assignment (The St. Louis Cardinals designated RP Peter Strzelecki for assignment.) | |
| 9/16/2026 | RP | Activated (The St. Louis Cardinals activated RP Peter Strzelecki from the 15-day injured list.) | |
| 9/8/2026 | SS | Activated (The St. Louis Cardinals activated SS Masyn Winn from the injured list.) | |
| 9/8/2026 | 3B | Sent to Minors (The St. Louis Cardinals optioned 3B Cesar Prieto to the minors.) | |
| 9/6/2026 | SP | Recalled From Minors Rehab (The St. Louis Cardinals recalled SP Cooper Hjerpe from the minors.) | |
| 9/6/2026 | SP | Sent to Minors (The St. Louis Cardinals optioned SP Hancel Rincon to the minors.) | |
| 9/4/2026 | RP | Sent to Minors (The St. Louis Cardinals optioned RP Ryan Fernandez to the minors.) | |
| 9/4/2026 | SP | Activated (The St. Louis Cardinals activated SP Andre Pallante from the injured list.) | |
| 9/1/2026 | C | Sent to Minors (The St. Louis Cardinals optioned C Jimmy Crooks to the minors.) | |
| 9/1/2026 | SP | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of RHP Hancel Rincon from the minors.) | |
| 9/1/2026 | C | Recalled From Minors Rehab (The St. Louis Cardinals recalled C Leonardo Bernal from the minors.) | |
| 9/1/2026 | CF | Recalled From Minors Rehab (The St. Louis Cardinals recalled OF Victor Scott from the minors.) | |
| 8/30/2026 | RP | Released (The St. Louis Cardinals released LHP Caleb Ferguson.) | |
| 8/30/2026 | 3B | Recalled From Minors Rehab (The St. Louis Cardinals recalled INF Cesar Prieto from the minors.) | |
| 8/30/2026 | 2B | Placed on 10-Day IL (The St. Louis Cardinals placed INF JJ Wetherholt on the 10-day injured list.) | |
| 8/29/2026 | RP | Designated for Assignment (The St. Louis Cardinals designated LHP Caleb Ferguson for assignment.) | |
| 8/29/2026 | SP | Recalled From Minors Rehab (The St. Louis Cardinals recalled LHP Brycen Mautz from the minors.) | |
| 8/28/2026 | 3B | Placed on 10-Day IL (The St. Louis Cardinals placed INF Blaze Jordan on the 10-day injured list.) | |
| 8/28/2026 | SS | Recalled From Minors Rehab (The St. Louis Cardinals recalled OF Thomas Saggese from the minors.) | |
| 8/27/2026 | SP | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of RHP Cade Winquest from the minors.) | |
| 8/27/2026 | RP | Placed on 15-Day IL (The St. Louis Cardinals placed RHP Peter Strzelecki on the 15-day injured list.) | |
| 8/25/2026 | SS | Placed on 10-Day IL (The St. Louis Cardinals placed INF Masyn Winn on the 10-day injured list.) | |
| 8/25/2026 | 3B | Recalled From Minors Rehab (The St. Louis Cardinals recalled INF Nolan Gorman from the minors.) | |
| 8/23/2026 | 3B | Activated (The St. Louis Cardinals activated INF Ramón Urías from the 60-day injured list.) | |
| 8/23/2026 | RF | Placed on 10-Day IL (The St. Louis Cardinals placed OF Everson Pereira on the 10-day injured list.) | |
| 8/22/2026 | SP | Placed on 15-Day IL (The St. Louis Cardinals placed RHP Hunter Dobbins on the 15-day injured list.) | |
| 8/22/2026 | SP | Recalled From Minors Rehab (The St. Louis Cardinals recalled LHP Quinn Mathews from the minors.) | |
| 8/21/2026 | RP | Recalled From Minors Rehab (The St. Louis Cardinals recalled RHP Ryan Fernandez from the minors.) | |
| 8/21/2026 | SP | Placed on 15-Day IL (The St. Louis Cardinals placed RHP Andre Pallante on the 15-day injured list.) | |
| 8/19/2026 | RP | Signed (The St. Louis Cardinals signed LHP Josh Fleming to a minor league contract.) | |
| 8/18/2026 | SP | Sent to Minors (The St. Louis Cardinals returned LHP Quinn Mathews to the minors, after he served as the 27th player in its doubleheader against the Reds.) | |
| 8/17/2026 | SP | Recalled From Minors Rehab (The St. Louis Cardinals appointed LHP Quinn Mathews from the minors. He will serve as the teams' 27th player in its doubleheader against the Reds.) | |
| 8/15/2026 | LF | Recalled From Minors Rehab (The St. Louis Cardinals recalled OF Joshua Baez from the minors.) | |
| 8/10/2026 | LF | Claimed on Unconditional Release Waivers (The Houston Astros claimed OF Nelson Velázquez off waivers from the St. Louis Cardinals.) To Houston | |
| 8/8/2026 | RF | Activated (The St. Louis Cardinals activated OF Everson Pereira from the minors.) | |
| 8/8/2026 | LF | Designated for Assignment (The St. Louis Cardinals designated OF Nelson Velázquez for assignment.) | |
| 8/6/2026 | SP | Sent to Minors (The St. Louis Cardinals sent RHP Tink Hence outright to the minors.) | |
| 8/6/2026 | RF | Claimed on Unconditional Release Waivers (The St. Louis Cardinals claimed OF Everson Pereira off waivers from the Chicago White Sox.) From Chi White Sox | |
| 8/4/2026 | SP | Sent to Minors (The St. Louis Cardinals optioned LHP Quinn Mathews to the minors.) | |
| 8/4/2026 | 3B | Recalled From Minors Rehab (The St. Louis Cardinals recalled INF Cesar Prieto from the minors.) | |
| 8/4/2026 | RP | Activated (The St. Louis Cardinals activated LHP Caleb Ferguson.) | |
| 8/3/2026 | SP | Traded (The Arizona Diamondbacks traded LHP Sandro Santana to the St. Louis Cardinals.) From Arizona | |
| 8/3/2026 | RP | Traded (The Cincinnati Reds traded LHP Caleb Ferguson to the St. Louis Cardinals.) From Cincinnati | |
| 8/3/2026 | SP | Traded (The Arizona Diamondbacks traded RHP Daniel Eagen to the St. Louis Cardinals.) From Arizona | |
| 8/3/2026 | 3B | Traded (The Arizona Diamondbacks traded INF Ruben Santana to the St. Louis Cardinals.) From Arizona | |
| 8/3/2026 | LF | Traded (The St. Louis Cardinals traded OF Lars Nootbaar to the Arizona Diamondbacks.) To Arizona | |
| 8/3/2026 | SP | Recalled From Minors Rehab (The St. Louis Cardinals recalled RHP Hunter Dobbins from the minors.) | |
| 8/3/2026 | CF | Traded (The Milwaukee Brewers traded OF Josiah Ragsdale to the St. Louis Cardinals.) From Milwaukee | |
| 8/3/2026 | CF | Traded (The Milwaukee Brewers traded OF Alexander Frias to the St. Louis Cardinals.) From Milwaukee | |
| 8/3/2026 | SP | Traded (The St. Louis Cardinals traded RHP Dustin May to the Milwaukee Brewers.) To Milwaukee | |
| 8/3/2026 | RP | Traded (The St. Louis Cardinals traded LHP JoJo Romero to the Milwaukee Brewers.) To Milwaukee | |
| 8/1/2026 | RP | Sent to Minors (The St. Louis Cardinals optioned RHP Matt Svanson to the minors.) | |
| 8/1/2026 | SP | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of LHP Quinn Mathews from the minors.) | |
| 8/1/2026 | SP | Designated for Assignment (The St. Louis Cardinals designated RHP Tink Hence for assignments.) | |
| 7/28/2026 | RP | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of RHP Peter Strzelecki from the minors.) | |
| 7/28/2026 | SP | Sent to Minors (The St. Louis Cardinals optioned RHP Hunter Dobbins to the minors.) | |
| 7/26/2026 | RP | Traded (The St. Louis Cardinals traded RHP Scott Blewett to the Athletics.) To Athletics | |
| 7/25/2026 | RP | Signed (The St. Louis Cardinals signed RHP Peter Strzelecki to a minor league contract.) | |
| 7/23/2026 | SP | Released (The St. Louis Cardinals released RHP Ian Bedell.) | |
| 7/23/2026 | C | Claimed on Unconditional Release Waivers (The Baltimore Orioles claimed C Yohel Pozo off waivers from the St. Louis Cardinals and optioned him to the minors.) To Baltimore | |
| 7/22/2026 | SP | Recalled From Minors Rehab (The St. Louis Cardinals recalled RHP Hunter Dobbins from the minors.) | |
| 7/22/2026 | RP | Designated for Assignment (The St. Louis Cardinals designated RHP Scott Blewett for assignment.) | |
| 7/17/2026 | SP | Traded (The Tampa Bay Rays traded RHP Trey Pooser to the St. Louis Cardinals.) From Tampa Bay | |
| 7/17/2026 | RP | Placed on 15-Day IL (The St. Louis Cardinals placed LHP JoJo Romero on the 15-day injured list.) | |
| 7/17/2026 | C | Designated for Assignment (The St. Louis Cardinals designated C Yohel Pozo for assignment.) | |
| 7/17/2026 | RP | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of RHP Scott Blewett from the minors.) | |
| 7/17/2026 | RF | Signed (The St. Louis Cardinals signed draft pick OF Caden Ferraro.) | |
| 7/17/2026 | SS | Signed (The St. Louis Cardinals signed draft pick INF Dee Kennedy.) | |
| 7/15/2026 | LF | Released (The St. Louis Cardinals released OF Matt Koperniak.) | |
| 7/13/2026 | RP | Drafted (The St. Louis Cardinals drafted RHP Nick Nick Bonn.) | |
| 7/13/2026 | RP | Sent to Minors (The St. Louis Cardinals sent LHP Bruce Zimmermann outright to the minors.) | |
| 7/12/2026 | 1B | Released (The St. Louis Cardinals released INF Bligh Madris.) | |
| 7/12/2026 | SP | Drafted (The St. Louis Cardinals drafted RHP Derek Schaefer.) | |
| 7/12/2026 | SP | Drafted (The St. Louis Cardinals drafted RHP Cal Randall.) | |
| 7/12/2026 | SS | Drafted (The St. Louis Cardinals drafted INF Owen Henne.) | |
| 7/11/2026 | SS | Drafted (The St. Louis Cardinals drafted INF Dee Kennedy.) | |
| 7/11/2026 | SP | Drafted (The St. Louis Cardinals drafted RHP Tegan Kuhns.) | |
| 7/11/2026 | RF | Drafted (The St. Louis Cardinals drafted OF Caden Ferraro.) | |
| 7/11/2026 | SS | Drafted (The St. Louis Cardinals drafted INF Rocco Maniscalco.) | |
| 7/11/2026 | SP | Drafted (The St. Louis Cardinals drafted RHP Dawson Montesa.) | |
| 7/11/2026 | CF | Drafted (The St. Louis Cardinals drafted OF Trevor Condon.) | |
| 7/11/2026 | RF | Drafted (The St. Louis Cardinals drafted OF Andrew Williamson.) | |
| 7/11/2026 | RP | Sent to Minors (The St. Louis Cardinals sent LHP Jared Shuster outright to the minors.) | |
| 7/8/2026 | RP | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of RHP Luis Gastelum from the minors.) | |
| 7/8/2026 | RP | Designated for Assignment (The St. Louis Cardinals designated LHP Jared Shuster for assignment.) | |
| 7/8/2026 | SP | Signed (The St. Louis Cardinals signed RHP Durbin Feltman to a minor league contract.) | |
| 7/8/2026 | SP | Sent to Minors (The St. Louis Cardinals returned RHP Hunter Dobbins to the minors, after he served as the 27th player in its doubleheader against the Brewers.) | |
| 7/7/2026 | LF | Released (The St. Louis Cardinals released OF Jose Cordoba.) | |
| 7/7/2026 | RP | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of LHP Jared Shuster from the minors.) | |
| 7/7/2026 | RP | Designated for Assignment (The St. Louis Cardinals designated LHP Bruce Zimmermann for assignment.) | |
| 7/7/2026 | RP | Sent to Minors (The St. Louis Cardinals optioned RHP Ryan Fernandez to the minors.) | |
| 7/7/2026 | SP | Placed on 60-Day IL (The St. Louis Cardinals transferred RHP Max Rajcic from the 10-day injured list to the 60-day injured list.) | |
| 7/7/2026 | SP | Recalled From Minors Rehab (The St. Louis Cardinals appointed RHP Hunter Dobbins from the minors, He will serve as the teams' 27th player in its doubleheader against the Brewers.) | |
| 7/7/2026 | RP | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of LHP Bruce Zimmermann from the minors.) | |
| 7/6/2026 | SP | Placed on 15-Day IL (The St. Louis Cardinals placed RHP Max Rajcic on the 15-day injured list.) | |
| 7/6/2026 | RP | Recalled From Minors Rehab (The St. Louis Cardinals recalled RHP Gordon Graceffo from the minors.) | |
| 7/3/2026 | RP | Sent to Minors (The St. Louis Cardinals optioned RHP Gordon Graceffo to the minors.) | |
| 7/3/2026 | RP | Activated (The St. Louis Cardinals reinstated RHP Ryne Stanek from the paternity list.) | |
| 6/30/2026 | RP | Activated (The St. Louis Cardinals activated RHP Ryan Fernandez from the 15-day injured list.) | |
| 6/30/2026 | RP | Placed on Paternity Leave List (The St. Louis Cardinals placed RHP Ryne Stanek on the Paternity Leave list.) | |
| 6/23/2026 | RP | Traded (The St. Louis Cardinals traded RHP Chris Roycroft to the Tampa Bay Rays. The Rays then optioned him to the minors.) To Tampa Bay | |
| 6/19/2026 | SS | Released (The St. Louis Cardinals released INF Miguel Villarroel.) | |
| 6/18/2026 | SP | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of RHP Max Rajcic from the minors.) | |
| 6/18/2026 | RP | Designated for Assignment (The St. Louis Cardinals designated RHP Chris Roycroft for assignment.) | |
| 6/18/2026 | RP | Sent to Minors (The St. Louis Cardinals optioned RHP Chris Roycroft to the minors.) | |
| 6/13/2026 | RP | Signed (The St. Louis Cardinals signed LHP Nathan Shinn to a minor league contract.) | |
| 6/12/2026 | 3B | Placed on 60-Day IL (The St. Louis Cardinals transferred INF Ramón Urías to the 60-day injured list.) | |
| 6/12/2026 | SP | Sent to Minors (The St. Louis Cardinals optioned RHP Hunter Dobbins to the minors.) | |
| 6/12/2026 | 3B | Sent to Minors (The St. Louis Cardinals optioned INF Nolan Gorman to the minors.) | |
| 6/12/2026 | 3B | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of INF Blaze Jordan from the minors.) | |
| 6/12/2026 | RP | Recalled From Minors Rehab (The St. Louis Cardinals recalled RHP Chris Roycroft from the minors.) | |
| 6/10/2026 | RP | Signed (The St. Louis Cardinals signed RHP Andrew Schultz to a minor league contract.) | |
| 6/9/2026 | SP | Released (The St. Louis Cardinals released RHP Gerson Moreno.) | |
| 6/9/2026 | CF | Activated (The St. Louis Cardinals activated OF Nathan Church from the 10-day injured list.) | |
| 6/8/2026 | CF | Sent to Minors (The St. Louis Cardinals optioned OF Victor Scott to the minors.) | |
| 6/5/2026 | LF | Activated (The St. Louis Cardinals activated OF Lars Nootbaar from the 60-day injured list.) | |
| 6/5/2026 | SS | Sent to Minors (The St. Louis Cardinals optioned OF Thomas Saggese to the minors.) | |
| 6/5/2026 | RP | Placed on 15-Day IL (The St. Louis Cardinals placed RHP Ryan Fernandez on the 15-day injured list.) | |
| 6/5/2026 | RP | Recalled From Minors Rehab (The St. Louis Cardinals recalled RHP Matt Svanson from the minors.) | |
| 5/31/2026 | RP | Designated for Assignment (The St. Louis Cardinals designated RHP Matt Pushard for assignment.) | |
| 5/31/2026 | SP | Recalled From Minors Rehab (The St. Louis Cardinals recalled RHP Hunter Dobbins from the minors.) | |
| 5/29/2026 | C | Sent to Minors (The St. Louis Cardinals optioned C Yohel Pozo to the minors.) | |
| 5/29/2026 | 3B | Sent to Minors (The St. Louis Cardinals optioned INF Cesar Prieto to the minors.) | |
| 5/29/2026 | LF | Recalled From Minors Rehab (The St. Louis Cardinals recalled OF Nelson Velázquez from the minors.) | |
| 5/29/2026 | C | Recalled From Minors Rehab (The St. Louis Cardinals recalled C Jimmy Crooks from the minors.) | |
| 5/25/2026 | RP | Recalled From Minors Rehab (The St. Louis Cardinals recalled RHP Ryan Fernandez from the minors.) | |
| 5/25/2026 | SP | Sent to Minors (The St. Louis Cardinals optioned LHP Brycen Mautz to the minors.) | |
| 5/24/2026 | RP | Sent to Minors (The St. Louis Cardinals sent RHP Ryan Fernandez to the minors.) | |
| 5/24/2026 | RP | Sent to Minors (The St. Louis Cardinals optioned RHP Matt Svanson to the minors.) | |
| 5/24/2026 | SP | Recalled From Minors Rehab (The St. Louis Cardinals recalled LHP Brycen Mautz from the minors.) | |
| 5/23/2026 | RP | Recalled From Minors Rehab (The St. Louis Cardinals recalled RHP Ryan Fernandez from the minors.) | |
| 5/21/2026 | LF | Recalled From Minors Rehab (The St. Louis Cardinals recalled OF Bryan Torres from the minors.) | |
| 5/21/2026 | CF | Placed on 10-Day IL (The St. Louis Cardinals placed OF Nathan Church on the 10-day injured list.) | |
| 5/18/2026 | RP | Sent to Minors (The St. Louis Cardinals outrighted LHP Jared Shuster to the minors.) | |
| 5/16/2026 | RP | Activated (The St. Louis Cardinals activated RHP Matt Pushard from the 15-day injured list.) | |
| 5/16/2026 | RP | Designated for Assignment (The St. Louis Cardinals designated LHP Jared Shuster for assignment.) | |
| 5/5/2026 | 3B | Placed on 10-Day IL (The St. Louis Cardinals placed INF Ramón Urías on the 10-day injured list.) | |
| 5/5/2026 | SS | Recalled From Minors Rehab (The St. Louis Cardinals recalled INF Thomas Saggese from the minors.) | |
| 5/4/2026 | 3B | Recalled From Minors Rehab (The St. Louis Cardinals recalled INF Cesar Prieto from the minors.) | |
| 5/4/2026 | SS | Sent to Minors (The St. Louis Cardinals optioned INF Thomas Saggese to the minors.) | |
| 5/3/2026 | SP | Claimed on Unconditional Release Waivers (The Chicago Cubs claimed LHP Luis Peralta off waivers from the St. Louis Cardinals and optioned him to the minors.) To Chi Cubs | |
| 5/1/2026 | RP | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of LHP Jared Shuster from the minors.) | |
| 5/1/2026 | SP | Designated for Assignment (The St. Louis Cardinals designated LHP Luis Peralta for assignment.) | |
| 4/30/2026 | RP | Sent to Minors (The St. Louis Cardinals optioned RHP Ryan Fernandez to the minors.) | |
| 4/30/2026 | SP | Activated (The St. Louis Cardinals activated RHP Hunter Dobbins from the 15-day injured list.) | |
| 4/27/2026 | SP | Sent to Minors (The St. Louis Cardinals optioned LHP Luis Peralta to the minors.) | |
| 4/27/2026 | SP | Claimed on Unconditional Release Waivers (The St. Louis Cardinals claimed LHP Luis Peralta off waivers.) | |
| 4/16/2026 | RP | Sent to Minors (The St. Louis Cardinals sent LHP Jared Shuster outright to the minors.) | |
| 4/13/2026 | SP | Other Transaction (The New York Yankees returned RHP Cade Winquest to the St. Louis Cardinals via Rule 5 draft.) From NY Yankees | |
| 4/13/2026 | RP | Recalled From Minors Rehab (The St. Louis Cardinals recalled RHP Ryan Fernandez from the minors.) | |
| 4/13/2026 | RP | Designated for Assignment (The St. Louis Cardinals designated LHP Jared Shuster for assignment.) | |
| 4/7/2026 | SP | Traded (The Baltimore Orioles traded INF Brayden Smith to the St. Louis Cardinals.) From Baltimore | |
| 4/7/2026 | SP | Traded (The St. Louis Cardinals traded LHP Nick Raquet to the Baltimore Orioles.) To Baltimore | |
| 4/5/2026 | RP | Traded (The Boston Red Sox traded RHP Patrick Galle to the St. Louis Cardinals.) From Boston | |
| 4/5/2026 | RP | Sent to Minors (The St. Louis Cardinals optioned RHP Chris Roycroft to the minors.) | |
| 4/5/2026 | SP | Designated for Assignment (The St. Louis Cardinals designated LHP Nick Raquet for assignment.) | |
| 4/5/2026 | RP | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of LHP Jared Shuster from the minors.) | |
| 3/31/2026 | RP | Placed on 15-Day IL (The St. Louis Cardinals placed RHP Matt Pushard on the 15-day injured list.) | |
| 3/31/2026 | RP | Recalled From Minors Rehab (The St. Louis Cardinals recalled RHP Gordon Graceffo from the minors.) | |
| 3/25/2026 | SS | Released (The St. Louis Cardinals released INF Yancel Guerrero.) | |
| 3/25/2026 | RP | Released (The St. Louis Cardinals released RHP Charles Harrison IV.) | |
| 3/25/2026 | Released (The St. Louis Cardinals released OF Andrew Sojka.) | ||
| 3/25/2026 | LF | Placed on 60-Day IL (The St. Louis Cardinals transferred OF Lars Nootbaar from the 10-day injured list to the 60-day injured list.) | |
| 3/25/2026 | SP | Placed on 15-Day IL (The St. Louis Cardinals placed RHP Hunter Dobbins on the 15-day injured list.) | |
| 3/24/2026 | 2B | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of INF JJ Wetherholt from the minors.) | |
| 3/21/2026 | RP | Sent to Minors (The St. Louis Cardinals optioned RHP Gordon Graceffo to the minors.) | |
| 3/21/2026 | LF | Placed on 10-Day IL (The St. Louis Cardinals placed OF Lars Nootbaar on the 10-day injured list.) | |
| 3/18/2026 | SP | Sent to Minors (The St. Louis Cardinals optioned RHP Richard Fitts to the minors.) | |
| 3/15/2026 | LF | Sent to Minors (The St. Louis Cardinals sent OF Matt Koperniak to the minors.) | |
| 3/15/2026 | RP | Sent to Minors (The St. Louis Cardinals optioned RHP Ryan Fernandez to the minors.) | |
| 3/15/2026 | RP | Sent to Minors (The St. Louis Cardinals sent LHP Packy Naughton to the minors.) | |
| 3/15/2026 | RP | Sent to Minors (The St. Louis Cardinals sent RHP Luis Gastelum to the minors.) | |
| 3/15/2026 | SS | Sent to Minors (The St. Louis Cardinals sent INF Jeremy Rivas to the minors.) | |
| 3/15/2026 | 3B | Sent to Minors (The St. Louis Cardinals sent INF Blaze Jordan to the minors.) | |
| 3/15/2026 | SP | Sent to Minors (The St. Louis Cardinals sent RHP Gerson Moreno to the minors.) | |
| 3/10/2026 | SP | Sent to Minors (The St. Louis Cardinals sent RHP Max Rajcic to the minors.) | |
| 3/10/2026 | RP | Sent to Minors (The St. Louis Cardinals sent LHP Bruce Zimmermann to the minors.) | |
| 3/10/2026 | CF | Sent to Minors (The St. Louis Cardinals sent OF Chase Davis to the minors.) | |
| 3/7/2026 | LF | Sent to Minors (The St. Louis Cardinals optioned OF Bryan Torres to the minors.) | |
| 3/7/2026 | C | Sent to Minors (The St. Louis Cardinals optioned C Jimmy Crooks to the minors.) | |
| 3/7/2026 | 3B | Sent to Minors (The St. Louis Cardinals optioned INF Cesar Prieto to the minors.) | |
| 3/7/2026 | C | Sent to Minors (The St. Louis Cardinals optioned C Leonardo Bernal to the minors.) | |
| 3/7/2026 | RP | Sent to Minors (The St. Louis Cardinals sent RHP Skylar Hales to the minors.) | |
| 3/7/2026 | SP | Sent to Minors (The St. Louis Cardinals optioned RHP Tink Hence to the minors.) | |
| 3/2/2026 | SP | Sent to Minors (The St. Louis Cardinals sent RHP Hancel Rincon to the minors.) | |
| 3/2/2026 | C | Sent to Minors (The St. Louis Cardinals sent C Graysen Tarlow to the minors.) | |
| 3/2/2026 | SP | Sent to Minors (The St. Louis Cardinals sent LHP Ixan Henderson to the minors.) | |
| 3/2/2026 | SP | Sent to Minors (The St. Louis Cardinals sent RHP Sem Robberse to the minors.) | |
| 3/2/2026 | RP | Sent to Minors (The St. Louis Cardinals sent RHP Austin Love to the minors.) | |
| 3/2/2026 | RP | Sent to Minors (The St. Louis Cardinals sent LHP Zack Thompson to the minors.) | |
| 3/2/2026 | RP | Sent to Minors (The St. Louis Cardinals sent LHP Jared Shuster to the minors.) | |
| 3/2/2026 | SP | Sent to Minors (The St. Louis Cardinals optioned RHP Tekoah Roby to the minors.) | |
| 3/2/2026 | CF | Sent to Minors (The St. Louis Cardinals sent OF Mike Antico to the minors.) | |
| 3/2/2026 | SP | Sent to Minors (The St. Louis Cardinals sent P Jurrangelo Cijntje to the minors.) | |
| 3/2/2026 | SP | Sent to Minors (The St. Louis Cardinals sent LHP Pete Hansen to the minors.) | |
| 2/26/2026 | SP | Claimed on Unconditional Release Waivers (The Minnesota Twins claimed RHP Zak Kent off waivers from the St. Louis Cardinals.) To Minnesota | |
| 2/21/2026 | SP | Designated for Assignment (The St. Louis Cardinals designated RHP Zak Kent for assignment.) | |
| 2/21/2026 | 3B | Sent to Minors (The St. Louis Cardinals sent INF Ramón Urías to the minors.) | |
| 2/21/2026 | 3B | Signed (The St. Louis Cardinals signed INF Ramón Urías from the minors.) | |
| 2/20/2026 | 3B | Claimed on Unconditional Release Waivers (The Baltimore Orioles claimed INF Bryan Ramos off waivers from the St. Louis Cardinals.) To Baltimore | |
| 2/16/2026 | 3B | Designated for Assignment (The St. Louis Cardinals designated INF Bryan Ramos for assignment.) | |
| 2/16/2026 | SP | Claimed on Unconditional Release Waivers (The St. Louis Cardinals claimed RHP Zak Kent off waivers from the Texas Rangers.) From Texas | |
| 2/10/2026 | RP | Traded (The St. Louis Cardinals traded RHP Andre Granillo to the Washington Nationals.) To Washington | |
| 2/10/2026 | RP | Traded (The Washington Nationals traded RHP George Soriano to the St. Louis Cardinals.) From Washington | |
| 2/6/2026 | 3B | Claimed on Unconditional Release Waivers (The St. Louis Cardinals claimed INF Bryan Ramos off waivers from the Baltimore Orioles.) From Baltimore | |
| 2/4/2026 | 1B | Signed (The St. Louis Cardinals signed INF Bligh Madris to a minor league contract.) | |
| 2/3/2026 | CF | Traded (The Tampa Bay Rays traded OF Colton Ledbetter to the St. Louis Cardinals.) From Tampa Bay | |
| 2/3/2026 | SS | Traded (The Seattle Mariners traded INF Tai Peete to the St. Louis Cardinals.) From Seattle | |
| 2/2/2026 | 3B | Traded (The St. Louis Cardinals traded INF Brendan Donovan to the Seattle Mariners.) To Seattle | |
| 2/2/2026 | SP | Traded (The Seattle Mariners traded P Jurrangelo Cijntje to the St. Louis Cardinals.) From Seattle | |
| 1/30/2026 | RP | Signed (The St. Louis Cardinals signed RHP Dominic Freeberger to a minor league contract.) | |
| 1/26/2026 | 2B | Non-roster Invitee (The St. Louis Cardinals invited INF Brody Moore to the team's spring training.) | |
| 1/26/2026 | SP | Non-roster Invitee (The St. Louis Cardinals invited LHP Ixan Henderson to the team's spring training.) | |
| 1/26/2026 | RP | Non-roster Invitee (The St. Louis Cardinals invited RHP Austin Love to the team's spring training.) | |
| 1/26/2026 | SP | Non-roster Invitee (The St. Louis Cardinals invited LHP Quinn Mathews to the team's spring training.) | |
| 1/26/2026 | SP | Non-roster Invitee (The St. Louis Cardinals invited RHP Gerson Moreno to the team's spring training.) | |
| 1/26/2026 | C | Non-roster Invitee (The St. Louis Cardinals invited C Carlos Linárez to the team's spring training.) | |
| 1/26/2026 | LF | Non-roster Invitee (The St. Louis Cardinals invited OF Matt Koperniak to the team's spring training.) | |
| 1/26/2026 | 2B | Non-roster Invitee (The St. Louis Cardinals invited INF JJ Wetherholt to the team's spring training.) | |
| 1/26/2026 | RP | Non-roster Invitee (The St. Louis Cardinals invited LHP Zack Thompson to the team's spring training.) | |
| 1/26/2026 | SS | Non-roster Invitee (The St. Louis Cardinals invited INF Jeremy Rivas to the team's spring training.) | |
| 1/26/2026 | RP | Non-roster Invitee (The St. Louis Cardinals invited RHP Skylar Hales to the team's spring training.) | |
| 1/26/2026 | SP | Non-roster Invitee (The St. Louis Cardinals invited LHP Pete Hansen to spring training.) | |
| 1/26/2026 | RP | Non-roster Invitee (The St. Louis Cardinals invited LHP Packy Naughton to the team's spring training.) | |
| 1/26/2026 | C | Non-roster Invitee (The St. Louis Cardinals invited C Graysen Tarlow to the team's spring training.) | |
| 1/26/2026 | RP | Non-roster Invitee (The St. Louis Cardinals invited RHP Luis Gastelum to the team's spring training.) | |
| 1/26/2026 | 3B | Non-roster Invitee (The St. Louis Cardinals invited INF Blaze Jordan to the team's spring training.) | |
| 1/26/2026 | SP | Non-roster Invitee (The St. Louis Cardinals invited RHP Max Rajcic to the team's spring training.) | |
| 1/26/2026 | CF | Signed (The St. Louis Cardinals signed OF Chase Davis to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | C | Signed (The St. Louis Cardinals signed C Andy Yerzy to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | RP | Signed (The St. Louis Cardinals signed RHP Austin Love to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | SP | Signed (The St. Louis Cardinals signed LHP Quinn Mathews to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | LF | Signed (The St. Louis Cardinals signed OF Matt Koperniak to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | RP | Signed (The St. Louis Cardinals signed LHP Packy Naughton to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | RP | Signed (The St. Louis Cardinals signed RHP Luis Gastelum to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | 2B | Signed (The St. Louis Cardinals signed INF Ramon Mendoza to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | CF | Signed (The St. Louis Cardinals signed OF Mike Antico to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | 2B | Signed (The St. Louis Cardinals signed INF Brody Moore to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | SP | Signed (The St. Louis Cardinals signed LHP Ixan Henderson to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | SP | Signed (The St. Louis Cardinals signed RHP Gerson Moreno to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | C | Signed (The St. Louis Cardinals signed C Carlos Linárez to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | 2B | Signed (The St. Louis Cardinals signed INF JJ Wetherholt to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | RP | Signed (The St. Louis Cardinals signed LHP Zack Thompson to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | SS | Signed (The St. Louis Cardinals signed INF Jeremy Rivas to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | RP | Signed (The St. Louis Cardinals signed RHP Skylar Hales to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | SP | Signed (The St. Louis Cardinals invited LHP Pete Hansen to spring training.) | |
| 1/26/2026 | C | Signed (The St. Louis Cardinals signed C Graysen Tarlow to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | 3B | Signed (The St. Louis Cardinals signed INF Blaze Jordan to the minor league contract with an invitation to spring training.) | |
| 1/26/2026 | SP | Signed (The St. Louis Cardinals signed RHP Max Rajcic to the minor league contract with an invitation to spring training.) | |
| 1/23/2026 | 1B | Retired (INF Jacob Buchberger retired from the MLB.) | |
| 1/13/2026 | 3B | Traded (The St. Louis Cardinals traded INF Nolan Arenado to the Arizona Diamondbacks.) To Arizona | |
| 1/13/2026 | RP | Sent to Minors (The St. Louis Cardinals assigned RHP Jack Martinez to the minors.) | |
| 1/13/2026 | RP | Traded (The Arizona Diamondbacks traded RHP Jack Martinez to the St. Louis Cardinals.) From Arizona | |
| 1/11/2026 | RP | Signed (The St. Louis Cardinals signed LHP Bruce Zimmermann to the minor league contract.) | |
| 1/9/2026 | RP | Signed (The St. Louis Cardinals signed RHP Ryne Stanek.) | |
| 1/9/2026 | SP | Claimed on Unconditional Release Waivers (The Texas Rangers claimed RHP Zak Kent off waivers from the St. Louis Cardinals.) To Texas | |
| 1/6/2026 | RP | Traded (The Cleveland Guardians traded LHP Justin Bruihl to the St. Louis Cardinals.) From Cleveland | |
| 1/6/2026 | SP | Designated for Assignment (The St. Louis Cardinals designated RHP Zak Kent for assignment.) | |
| 12/22/2025 | RP | Signed (The St. Louis Cardinals signed LHP Jared Shuster. to a minor league contract with an invitation to spring training.) | |
| 12/22/2025 | 1B | Traded (The St. Louis Cardinals traded INF Willson Contreras to the Boston Red Sox.) To Boston | |
| 12/22/2025 | SP | Traded (The Boston Red Sox traded RHP Yhoiker Fajardo to the St. Louis Cardinals.) From Boston | |
| 12/22/2025 | SP | Traded (The Boston Red Sox traded RHP Hunter Dobbins to the St. Louis Cardinals.) From Boston | |
| 12/22/2025 | SP | Traded (The Boston Red Sox traded RHP Blake Aita to the St. Louis Cardinals.) From Boston | |
| 12/19/2025 | LF | Sent to Minors (The St. Louis Cardinals sent OF Matt Koperniak outright to the minors.) | |
| 12/17/2025 | LF | Designated for Assignment (The St. Louis Cardinals designated OF Matt Koperniak for assignment.) | |
| 12/13/2025 | SP | Signed (The St. Louis Cardinals signed RHP Dustin May.) | |
| 12/11/2025 | RP | Drafted Via Rule 5 (The Chicago Cubs selected RHP Zane Mills in the Rule 5 Draft.) To Chi Cubs | |
| 12/11/2025 | RP | Drafted Via Rule 5 (The Arizona Diamondbacks selected RHP Sean Harney in the Rule 5 Draft.) To Arizona | |
| 12/11/2025 | 3B | Drafted Via Rule 5 (The Boston Red Sox selected OF Matt Lloyd in the Rule 5 Draft.) To Boston | |
| 12/10/2025 | SP | Drafted Via Rule 5 (The St. Louis Cardinals selected RHP Ryan Murphy in the Rule 5 Draft.) From San Francisco | |
| 12/10/2025 | SP | Drafted Via Rule 5 (The New York Yankees selected RHP Cade Winquest in the Rule 5 Draft.) To NY Yankees | |
| 12/10/2025 | RP | Drafted Via Rule 5 (The St. Louis Cardinals selected RHP Matt Pushard in the Rule 5 Draft.) From Miami | |
| 12/5/2025 | SP | Claimed on Unconditional Release Waivers (The St. Louis Cardinals claimed RHP Zak Kent off waivers from the Cleveland Guardians.) From Cleveland | |
| 11/25/2025 | SP | Sent to Minors (The St. Louis Cardinals assigned LHP Brandon Clarke to the minors.) | |
| 11/25/2025 | SP | Traded (The Boston Red Sox traded RHP Richard Fitts to the St. Louis Cardinals.) From Boston | |
| 11/25/2025 | SP | Traded (The Boston Red Sox traded LHP Brandon Clarke to the St. Louis Cardinals.) From Boston | |
| 11/25/2025 | SP | Traded (The St. Louis Cardinals traded RHP Sonny Gray to the Boston Red Sox.) To Boston | |
| 11/25/2025 | RP | Signed (The St. Louis Cardinals signed RHP Scott Blewett to a minor league contract with a spring training invite..) | |
| 11/25/2025 | SP | Signed (The St. Louis Cardinals signed RHP Sem Robberse to a minor league contract and an invitation to spring training.) | |
| 11/25/2025 | C | Signed (The St. Louis Cardinals signed C Yohel Pozo.) | |
| 11/21/2025 | RP | Released (The St. Louis Cardinals released LHP John King.) | |
| 11/21/2025 | RP | Released (The St. Louis Cardinals released RHP Jorge Alcala.) | |
| 11/21/2025 | SP | Released (The St. Louis Cardinals released RHP Sem Robberse.) | |
| 11/21/2025 | C | Released (The St. Louis Cardinals released C Yohel Pozo.) | |
| 11/21/2025 | C | Signed (The St. Louis Cardinals signed C Andy Yerzy to a minor league contract.) From Cincinnati | |
| 11/21/2025 | 2B | Signed (The St. Louis Cardinals have signed INF Ramon Mendoza to a minor league contract.) | |
| 11/21/2025 | SP | Signed (The St. Louis Cardinals signed RHP Gerson Moreno to a minor league contract.) | |
| 11/19/2025 | SP | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of LHP Brycen Mautz from the minors.) | |
| 11/19/2025 | SP | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of LHP Cooper Hjerpe from the minors.) | |
| 11/19/2025 | C | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of C Leonardo Bernal from the minors.) | |
| 11/19/2025 | RP | Designated for Assignment (The St. Louis Cardinals designated RHP Jorge Alcala for assignment.) | |
| 11/19/2025 | LF | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of OF Joshua Baez from the minors.) | |
| 11/6/2025 | SP | Released (The St. Louis Cardinals released LHP Anthony Veneziano.) | |
| 11/6/2025 | CF | Claimed on Unconditional Release Waivers (The Atlanta Braves claimed OF Michael Siani off waivers from the St. Louis Cardinals.) To Atlanta | |
| 11/6/2025 | RP | Released (The St. Louis Cardinals released LHP Zack Thompson.) | |
| 11/6/2025 | LF | Recalled From Minors Rehab (The St. Louis Cardinals selected the contract of C Bryan Torres from the minors.) | |
| 11/6/2025 | RP | Claimed on Unconditional Release Waivers (The Cincinnati Reds claimed RHP Roddery Muñoz off waivers from the St. Louis Cardinals.) To Cincinnati | |
| 11/2/2025 | SP | Declared Free Agency (RHP Miles Mikolas elected free agency.) |