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Amylyx Pharmaceuticals, Inc. (AMLX)

28.07 -0.23 (-0.81%)
At close: October 28 at 4:00:01 PM EDT
28.25 +0.18 (+0.64%)
Overnight: 2:08:36 AM EDT
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Chart Range Bar
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  • Previous Close 28.30
  • Open 28.48
  • Bid 20.02 x 200
  • Ask 35.35 x 200
  • Day's Range 27.58 - 28.48
  • 52 Week Range 10.83 - 41.14
  • Volume 1,064,204
  • Avg. Volume 2,246,716
  • Market Cap (intraday) 3.523B
  • Beta (5Y Monthly) -0.09
  • PE Ratio (TTM) --
  • EPS (TTM) -1.41
  • Earnings Date Nov 5, 2026
  • Forward Dividend & Yield -- (0.00%)
  • 1y Target Est 43.00
  • Zacks Rating Neutral

Amylyx Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, engages in the discovery and development of treatment options for neurodegenerative diseases and endocrine conditions in the United States. It provides Avexitide, an investigational, first-in-class glucagon-like peptide-1, or GLP-1 receptor antagonist, which is in phase 3 clinical trial to treat post-bariatric hypoglycemia and congenital hyperinsulinism. The company also develops AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol which is phase 2 clinical trial for the treatment of wolfram syndrome, as well as in phase 2b/3 clinical trial to treat progressive supranuclear palsy; AMX0114, which is in phase 1 clinical trial for the treatment of amyotrophic lateral sclerosis; and long-acting GLP-1 receptor antagonist to treat post-bariatric hypoglycemia and other rare diseases. Further, it develops AMX0318, a GLP-1 receptor antagonist for the treatment of post-bariatric hypoglycemia and other rare diseaees. Amylyx Pharmaceuticals, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.

amylyx.com

136

Full Time Employees

December 31

Fiscal Year Ends

Healthcare

Sector

Recent News

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Performance Overview

Trailing total returns as of 10/28/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC) .

YTD Return

AMLX
132.37%
S&P 500 (^GSPC)
13.13%

1-Year Return

AMLX
96.02%
S&P 500 (^GSPC)
12.38%

3-Year Return

AMLX
78.34%
S&P 500 (^GSPC)
88.08%

5-Year Return

AMLX
33.67%
S&P 500 (^GSPC)
68.48%

Earnings Trends

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Earnings Per Share

GAAP
Normalized
GAAP
Normalized

Revenue vs. Earnings

Annual
Quarterly
Annual
Quarterly
Q2 FY26
Revenue --
Earnings -43.42M
Profit Margin 0.00%

Q3

FY25

Q4

FY25

Q1

FY26

Q2

FY26

-40M
-30M
-20M
-10M
0
0.0%

Analyst Insights

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Analyst Price Targets

20.00 Low
43.00 Average
28.07 Current
57.00 High

Analyst Recommendations

  • Strong Buy
  • Buy
  • Hold
  • Underperform
  • Sell

Latest Rating

Date 10/15/2026
Analyst Citigroup
Rating Action Maintains
Rating Buy
Price Action Raises
Price Target 32 -> 39

Statistics

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Valuation Measures

Annual
  • Market Cap

  • Enterprise Value

  • Trailing P/E

  • Forward P/E

  • PEG Ratio (current)

  • Price/Sales (ttm)

  • Price/Book (mrq)

  • Enterprise Value/Revenue

  • Enterprise Value/EBITDA

Financial Highlights

Profitability and Income Statement

  • Profit Margin

    0.00%

  • Return on Assets (ttm)

    -44.13%

  • Return on Equity (ttm)

    -74.73%

  • Revenue (ttm)

    --

  • Net Income Avi to Common (ttm)

    -152.09M

  • Diluted EPS (ttm)

    -1.41

Balance Sheet and Cash Flow

  • Total Cash (mrq)

    250.76M

  • Total Debt/Equity (mrq)

    2.20%

  • Levered Free Cash Flow (ttm)

    -77.32M

Company Insights

Research Reports

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