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Lexicon Pharmaceuticals, Inc. (LXRX)

1.4200 -0.0600 (-4.05%)
At close: October 30 at 4:00:00 PM EDT
1.5000 +0.0800 (+5.63%)
After hours: October 30 at 7:30:42 PM EDT
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What's happening with LXRX?

45m ago
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Lexicon Pharmaceuticals is approaching two major catalysts: third-quarter results on November 5, 2026, and topline SONATA-HCM data expected in the first quarter of 2027. The company has substantially exceeded enrollment targets for its pivotal heart-disease study, while its broader pipeline remains dependent on clinical and regulatory milestones.

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  • Previous Close 1.4800
  • Open 1.4700
  • Bid 1.2300 x 100
  • Ask 1.4200 x 200
  • Day's Range 1.3750 - 1.4961
  • 52 Week Range 1.1000 - 2.6800
  • Volume 2,443,845
  • Avg. Volume 2,710,779
  • Market Cap (intraday) 631.837M
  • Beta (5Y Monthly) 1.08
  • PE Ratio (TTM) --
  • EPS (TTM) -0.1600
  • Earnings Date Nov 5, 2026
  • Forward Dividend & Yield -- (0.00%)
  • 1y Target Est 4.47
  • Zacks Rating Neutral

Lexicon Pharmaceuticals, Inc., a biopharmaceutical company, focuses on the discovery, development, and commercialization of pharmaceutical products for the treatment of human disease. The company develops sotagliflozin, an orally-delivered small molecule drug for the treatment of hypertrophic cardiomyopathy, and ZYNQUISTA (sotagliflozin) for the treatment of type 1 diabetes. It also commercializes INPEFA (sotagliflozin), a once-daily oral tablet to reduce the risk of cardiovascular death, hospitalization for heart failure, and urgent heart failure visit in adults with heart failure or type 2 diabetes, CKD, and other cardiovascular risk factors. In addition, the company develops LX9851, an orally-delivered small molecule drug candidate for the treatment of obesity and associated cardiometabolic disorders, and pilavapadin (LX9211), an orally-delivered small molecule drug candidate for the treatment of neuropathic pain. It has strategic collaboration and license agreements with Viatris Inc. and Bristol-Myers Squibb Company. The company was incorporated in 1995 and is headquartered in The Woodlands, Texas.

www.lexpharma.com

81

Full Time Employees

December 31

Fiscal Year Ends

Healthcare

Sector

Biotechnology

Industry

Recent News

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Performance Overview

Trailing total returns as of 10/30/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC) .

YTD Return

LXRX
23.48%
S&P 500 (^GSPC)
10.73%

1-Year Return

LXRX
5.97%
S&P 500 (^GSPC)
11.11%

3-Year Return

LXRX
18.33%
S&P 500 (^GSPC)
81.91%

5-Year Return

LXRX
73.16%
S&P 500 (^GSPC)
64.59%

Earnings Trends

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Earnings Per Share

GAAP
Normalized
GAAP
Normalized

Revenue vs. Earnings

Annual
Quarterly
Annual
Quarterly
Q2 FY26
Revenue 692k
Earnings -31.77M
Profit Margin -4,591.76%

Q3

FY25

Q4

FY25

Q1

FY26

Q2

FY26

-30M
-20M
-10M
0
10M
20M
-4000.0%
-3000.0%
-2000.0%
-1000.0%

Analyst Insights

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Analyst Price Targets

1.69
4.47 Average
1.4200 Current
8.00 High

Analyst Recommendations

  • Strong Buy
  • Buy
  • Hold
  • Underperform
  • Sell

Latest Rating

Date 9/28/2026
Analyst Cantor Fitzgerald
Rating Action Initiated
Rating Overweight
Price Action Announces
Price Target 8

Statistics

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Valuation Measures

Annual
  • Market Cap

  • Enterprise Value

  • Trailing P/E

  • Forward P/E

  • PEG Ratio (current)

  • Price/Sales (ttm)

  • Price/Book (mrq)

  • Enterprise Value/Revenue

  • Enterprise Value/EBITDA

Financial Highlights

Profitability and Income Statement

  • Profit Margin

    -147.38%

  • Return on Assets (ttm)

    -14.32%

  • Return on Equity (ttm)

    -40.21%

  • Revenue (ttm)

    41.47M

  • Net Income Avi to Common (ttm)

    -61.12M

  • Diluted EPS (ttm)

    -0.1600

Balance Sheet and Cash Flow

  • Total Cash (mrq)

    190.61M

  • Total Debt/Equity (mrq)

    33.94%

  • Levered Free Cash Flow (ttm)

    -44.77M

Company Insights

Research Reports

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