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Talphera, Inc. (TLPH)

1.0500 +0.0400 (+3.96%)
At close: November 6 at 4:00:00 PM EST
1.0600 +0.0100 (+0.95%)
After hours: November 6 at 5:46:37 PM EST
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  • Previous Close 1.0100
  • Open 1.0000
  • Bid 1.0700 x 100
  • Ask 1.0400 x 100
  • Day's Range 1.0000 - 1.0600
  • 52 Week Range 0.6900 - 1.5700
  • Volume 79,421
  • Avg. Volume 166,209
  • Market Cap (intraday) 54.501M
  • Beta (5Y Monthly) 0.73
  • PE Ratio (TTM) --
  • EPS (TTM) -0.2600
  • Earnings Date Nov 12, 2026
  • Forward Dividend & Yield -- (0.00%)
  • 1y Target Est 3.12
  • Motley Fool Rating Bearish

Talphera, Inc., a specialty pharmaceutical company, focuses on the development and commercialization of therapies for use in medically supervised settings. The company's lead product candidate, Niyad, is a lyophilized formulation of nafamostat that acts as a regional anticoagulant for infusion into the extracorporeal circuit. It is also developing LTX-608, a lyophilized vial containing nafamostat for IV infusion for disseminated intravascular coagulation, acute respiratory distress syndrome, acute pancreatitis, and an anti-viral treatment; Fedsyra, an ephedrine pre-filled syringe for injection; and a phenylephrine pre-filled syringe for injection. The company was formerly known as AcelRx Pharmaceuticals, Inc. and changed its name to Talphera, Inc. in January 2024. The company was incorporated in 2005 and is headquartered in San Mateo, California.

talphera.com

12

Full Time Employees

December 31

Fiscal Year Ends

Healthcare

Sector

Recent News

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Performance Overview

Trailing total returns as of 11/6/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC) .

YTD Return

TLPH
7.89%
S&P 500 (^GSPC)
7.76%

1-Year Return

TLPH
9.48%
S&P 500 (^GSPC)
9.77%

3-Year Return

TLPH
110.00%
S&P 500 (^GSPC)
68.96%

5-Year Return

TLPH
93.90%
S&P 500 (^GSPC)
57.04%

Earnings Trends

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Earnings Per Share

GAAP
Normalized
GAAP
Normalized

Revenue vs. Earnings

Annual
Quarterly
Annual
Quarterly
Q4 FY25
Revenue --
Earnings -3.77M
Profit Margin 0.00%

Q1

FY25

Q2

FY25

Q3

FY25

Q4

FY25

-4M
-3M
-2M
-1M
0
-400000.0%
-300000.0%
-200000.0%
-100000.0%
0.0%

Analyst Insights

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Analyst Price Targets

3.00
3.12 Average
1.0500 Current
3.50 High

Analyst Recommendations

  • Strong Buy
  • Buy
  • Hold
  • Underperform
  • Sell

Latest Rating

Date 4/30/2026
Analyst WestPark Capital
Rating Action Initiated
Rating Buy
Price Action Announces
Price Target 3

Statistics

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Valuation Measures

Annual
  • Market Cap

  • Enterprise Value

  • Trailing P/E

  • Forward P/E

  • PEG Ratio (current)

  • Price/Sales (ttm)

  • Price/Book (mrq)

  • Enterprise Value/Revenue

  • Enterprise Value/EBITDA

Financial Highlights

Profitability and Income Statement

  • Profit Margin

    0.00%

  • Return on Assets (ttm)

    -42.55%

  • Return on Equity (ttm)

    -143.36%

  • Revenue (ttm)

    1k

  • Net Income Avi to Common (ttm)

    -15.08M

  • Diluted EPS (ttm)

    -0.2600

Balance Sheet and Cash Flow

  • Total Cash (mrq)

    17.08M

  • Total Debt/Equity (mrq)

    45.11%

  • Levered Free Cash Flow (ttm)

    -6.87M

Company Insights

Research Reports

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