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Xilio Therapeutics, Inc. (XLO)

7.05 -0.88 (-11.10%)
As of 9:57:59 AM EDT. Market Open.
Chart Range Bar
Loading chart for XLO
  • Previous Close 7.93
  • Open 7.05
  • Bid 7.55 x 100
  • Ask 8.46 x 400
  • Day's Range 7.05 - 7.05
  • 52 Week Range 6.47 - 12.32
  • Volume 591
  • Avg. Volume 12,462
  • Market Cap (intraday) 46.391M
  • Beta (5Y Monthly) -0.12
  • PE Ratio (TTM) --
  • EPS (TTM) -0.60
  • Earnings Date (est.) --
  • Forward Dividend & Yield -- (0.00%)
  • 1y Target Est 18.00
  • Zacks Rating Neutral

Xilio Therapeutics, Inc., a clinical-stage biotechnology company, engages in the discovery and development of masked immuno-oncology therapies. The company's pipeline includes XTX501, a bispecific PD-1 / masked IL-2, for patients with metastatic non-small cell lung cancer; Efarindodekin alfa, an investigational, masked IL-12, that is in Phase 2 clinical trial for patients with advanced solid tumors; and Vilastobart, an investigational tumor-activated, Fc-enhanced, high affinity binding anti-CTLA-4 monoclonal antibody. The company was founded in 2016 and is headquartered in Waltham, Massachusetts.

xiliotx.com

76

Full Time Employees

December 31

Fiscal Year Ends

Healthcare

Sector

Biotechnology

Industry

Recent News

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Performance Overview

Trailing total returns as of 10/30/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC) .

YTD Return

XLO
21.32%
S&P 500 (^GSPC)
11.30%

1-Year Return

XLO
37.37%
S&P 500 (^GSPC)
11.68%

3-Year Return

XLO
76.02%
S&P 500 (^GSPC)
82.85%

5-Year Return

XLO
97.00%
S&P 500 (^GSPC)
65.44%

Earnings Trends

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Earnings Per Share (GAAP)

Revenue vs. Earnings

Annual
Quarterly
Annual
Quarterly
Q3 FY25
Revenue 19.07M
Earnings -16.29M
Profit Margin -85.42%

Q4

FY24

Q1

FY25

Q2

FY25

Q3

FY25

-10M
0
10M
-600.0%
-400.0%
-200.0%

Analyst Insights

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Analyst Price Targets

16.00
18.00 Average
7.05 Current
20.00 High

Analyst Recommendations

  • Strong Buy
  • Buy
  • Hold
  • Underperform
  • Sell

Latest Rating

Date 10/21/2026
Analyst Raymond James
Rating Action Initiated
Rating Outperform
Price Action Announces
Price Target 16

Statistics

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Valuation Measures

Annual
  • Market Cap

  • Enterprise Value

  • Trailing P/E

  • Forward P/E

  • PEG Ratio (current)

  • Price/Sales (ttm)

  • Price/Book (mrq)

  • Enterprise Value/Revenue

  • Enterprise Value/EBITDA

Financial Highlights

Profitability and Income Statement

  • Profit Margin

    -34.06%

  • Return on Assets (ttm)

    -13.61%

  • Return on Equity (ttm)

    -55.03%

  • Revenue (ttm)

    64.09M

  • Net Income Avi to Common (ttm)

    -21.83M

  • Diluted EPS (ttm)

    -0.60

Balance Sheet and Cash Flow

  • Total Cash (mrq)

    136.04M

  • Total Debt/Equity (mrq)

    8.72%

  • Levered Free Cash Flow (ttm)

    -37.56M

Company Insights

Research Reports

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