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Spero Therapeutics, Inc. (SPRO)

2.7800 +0.0600 (+2.21%)
At close: April 9 at 4:00:00 PM EDT
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Chart Range Bar
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  • Previous Close 2.7200
  • Open 2.7200
  • Bid 2.7500 x 100
  • Ask 2.8300 x 100
  • Day's Range 2.6700 - 2.8000
  • 52 Week Range 0.5220 - 3.2200
  • Volume 446,503
  • Avg. Volume 330,206
  • Market Cap (intraday) 160.938M
  • Beta (5Y Monthly) 1.45
  • PE Ratio (TTM) 18.53
  • EPS (TTM) 0.1500
  • Earnings Date (est.) May 13, 2026
  • Forward Dividend & Yield --
  • Ex-Dividend Date --
  • 1y Target Est 4.00

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which is in Phase 3 development; and SPR720, a novel product candidate for first-line treatment of nontuberculous mycobacterial (NTM) pulmonary disease. It has license agreement with Meiji Seika Pharma Co., Ltd. to support the development of tebipenem HBr; Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries; and Vertex Pharmaceuticals Incorporated for patents relating to the oral prodrug SPR720, as well as SPR719, an active metabolite. Spero Therapeutics, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.

sperotherapeutics.com

25

Full Time Employees

December 31

Fiscal Year Ends

Healthcare

Sector

Biotechnology

Industry

Performance Overview: SPRO

Trailing total returns as of 4/9/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC) .

YTD Return

SPRO
19.31%
S&P 500 (^GSPC)
0.30%

1-Year Return

SPRO
371.19%
S&P 500 (^GSPC)
25.06%

3-Year Return

SPRO
84.11%
S&P 500 (^GSPC)
66.25%

5-Year Return

SPRO
78.75%
S&P 500 (^GSPC)
65.29%

Earnings Trends: SPRO

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Earnings Per Share

GAAP
Normalized
GAAP
Normalized

Revenue vs. Earnings

Annual
Quarterly
Annual
Quarterly
Q3 FY25
Revenue 5.44M
Earnings --

Q4

FY24

Q1

FY25

Q2

FY25

Q3

FY25

-20M
-10M
0
10M

Analyst Insights: SPRO

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Analyst Price Targets

4.00
4.00 Average
2.7800 Current
4.00 High

Analyst Recommendations

  • Strong Buy
  • Buy
  • Hold
  • Underperform
  • Sell

Latest Rating

Date 1/30/2025
Analyst HC Wainwright & Co.
Rating Action Reiterates
Rating Buy
Price Action Maintains
Price Target 5 -> 5

Statistics: SPRO

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Valuation Measures

Annual
As of 4/9/2026
  • Market Cap

    160.94M

  • Enterprise Value

    123.57M

  • Trailing P/E

    18.53

  • Forward P/E

    --

  • PEG Ratio (5yr expected)

    --

  • Price/Sales (ttm)

    2.75

  • Price/Book (mrq)

    2.73

  • Enterprise Value/Revenue

    2.07

  • Enterprise Value/EBITDA

    17.26

Financial Highlights

Profitability and Income Statement

  • Profit Margin

    12.83%

  • Return on Assets (ttm)

    4.99%

  • Return on Equity (ttm)

    16.30%

  • Revenue (ttm)

    66.8M

  • Net Income Avi to Common (ttm)

    8.57M

  • Diluted EPS (ttm)

    0.1500

Balance Sheet and Cash Flow

  • Total Cash (mrq)

    40.27M

  • Total Debt/Equity (mrq)

    4.91%

  • Levered Free Cash Flow (ttm)

    -4.25M

Compare To: SPRO

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Company Insights: SPRO

Fair Value

2.7800 Current

Dividend Score

0 Low
Sector Avg.
100 High

Hiring Score

0 Low
Sector Avg.
100 High

Insider Sentiment Score

0 Low
Sector Avg.
100 High

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