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Spero Therapeutics, Inc. (SPRO)

1.0600 -0.0500 (-4.50%)
At close: October 30 at 4:00:01 PM EDT
1.0795 +0.0195 (+1.84%)
After hours: October 30 at 5:47:23 PM EDT
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Chart Range Bar
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  • Previous Close 1.1100
  • Open 1.1100
  • Bid 1.0700 x 200
  • Ask 1.0700 x 100
  • Day's Range 1.0500 - 1.1150
  • 52 Week Range 1.0400 - 3.0800
  • Volume 308,863
  • Avg. Volume 603,952
  • Market Cap (intraday) 61.729M
  • Beta (5Y Monthly) 1.50
  • PE Ratio (TTM) 7.57
  • EPS (TTM) 0.1400
  • Earnings Date (est.) Nov 12, 2026
  • Forward Dividend & Yield -- (0.00%)
  • 1y Target Est 5.33
  • Motley Fool Rating Bullish

Spero Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on identifying and developing novel treatments for multi-drug resistant (MDR) bacterial infections and rare diseases in the United States. The company's product candidates include Tebipenem HBr (tebipenem pivoxil hydrobromide), an oral carbapenem-class antibiotic to treat complicated urinary tract infections, including pyelonephritis for adult patients, which has completed second Phase 3 trial. It has license agreement with Meiji Seika Pharma Co., Ltd. to develop, manufacture, and commercialize tebipenem pivoxil and tebipenem HBr; and Everest Medicines to develop, manufacture, and commercialize SPR206 in Greater China, South Korea, and Southeast Asian countries. Spero Therapeutics, Inc. was incorporated in 2013 and is headquartered in Cambridge, Massachusetts.

sperotherapeutics.com

25

Full Time Employees

December 31

Fiscal Year Ends

Healthcare

Sector

Biotechnology

Industry

Recent News

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Performance Overview

Trailing total returns as of 10/30/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC) .

YTD Return

SPRO
54.51%
S&P 500 (^GSPC)
10.73%

1-Year Return

SPRO
55.08%
S&P 500 (^GSPC)
11.11%

3-Year Return

SPRO
2.91%
S&P 500 (^GSPC)
81.91%

5-Year Return

SPRO
93.96%
S&P 500 (^GSPC)
64.59%

Earnings Trends

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Earnings Per Share

GAAP
Normalized
GAAP
Normalized

Revenue vs. Earnings

Annual
Quarterly
Annual
Quarterly
Q2 FY26
Revenue --
Earnings --
Profit Margin 0.00%

Q1

FY25

Q2

FY25

Q3

FY25

Q2

FY26

-10M
-5M
0
5M
10M
-200.0%
-150.0%
-100.0%
-50.0%
0.0%

Analyst Insights

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Analyst Price Targets

4.00
5.33 Average
1.0600 Current
6.00 High

Analyst Recommendations

  • Strong Buy
  • Buy
  • Hold
  • Underperform
  • Sell

Latest Rating

Date 10/28/2026
Analyst Cantor Fitzgerald
Rating Action Initiated
Rating Overweight
Price Action Announces
Price Target 6

Statistics

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Valuation Measures

Annual
  • Market Cap

  • Enterprise Value

  • Trailing P/E

  • Forward P/E

  • PEG Ratio (current)

  • Price/Sales (ttm)

  • Price/Book (mrq)

  • Enterprise Value/Revenue

  • Enterprise Value/EBITDA

Financial Highlights

Profitability and Income Statement

  • Profit Margin

    15.71%

  • Return on Assets (ttm)

    7.19%

  • Return on Equity (ttm)

    19.17%

  • Revenue (ttm)

    47M

  • Net Income Avi to Common (ttm)

    7.38M

  • Diluted EPS (ttm)

    0.1400

Balance Sheet and Cash Flow

  • Total Cash (mrq)

    50.77M

  • Total Debt/Equity (mrq)

    4.62%

  • Levered Free Cash Flow (ttm)

    28.85M

Company Insights

Research Reports

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