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Amylyx Pharmaceuticals, Inc. (AMLX)

34.10 +0.14 (+0.41%)
At close: September 4 at 4:00:01 PM EDT
34.25 +0.15 (+0.44%)
After hours: September 4 at 7:48:29 PM EDT
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Chart Range Bar
Loading chart for AMLX
  • Previous Close 33.96
  • Open 33.38
  • Bid 24.16 x 200
  • Ask 42.99 x 200
  • Day's Range 33.38 - 34.24
  • 52 Week Range 10.07 - 41.14
  • Volume 885,093
  • Avg. Volume 2,468,620
  • Market Cap (intraday) 3.8B
  • Beta (5Y Monthly) -0.12
  • PE Ratio (TTM) --
  • EPS (TTM) -1.41
  • Earnings Date Nov 5, 2026
  • Forward Dividend & Yield --
  • Ex-Dividend Date --
  • 1y Target Est 42.36

Amylyx Pharmaceuticals, Inc., a clinical-stage pharmaceutical company, engages in the discovery and development of treatment options for neurodegenerative diseases and endocrine conditions in the United States. It provides Avexitide, an investigational, first-in-class glucagon-like peptide-1, or GLP-1 receptor antagonist, which is in phase 3 clinical trial to treat post-bariatric hypoglycemia and congenital hyperinsulinism. The company also develops AMX0035, an oral, fixed-dose combination of sodium phenylbutyrate and taurursodiol which is phase 2 clinical trial for the treatment of wolfram syndrome, as well as in phase 2b/3 clinical trial to treat progressive supranuclear palsy; AMX0114, which is in phase 1 clinical trial for the treatment of amyotrophic lateral sclerosis; and long-acting GLP-1 receptor antagonist to treat post-bariatric hypoglycemia and other rare diseases. Further, it develops AMX0318, a GLP-1 receptor antagonist for the treatment of post-bariatric hypoglycemia and other rare diseaees. Amylyx Pharmaceuticals, Inc. was founded in 2013 and is headquartered in Cambridge, Massachusetts.

amylyx.com

136

Full Time Employees

December 31

Fiscal Year Ends

Healthcare

Sector

Performance Overview

Trailing total returns as of 9/4/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC) .

YTD Return

AMLX
182.28%
S&P 500 (^GSPC)
12.75%

1-Year Return

AMLX
242.71%
S&P 500 (^GSPC)
18.71%

3-Year Return

AMLX
56.28%
S&P 500 (^GSPC)
70.93%

5-Year Return

AMLX
62.38%
S&P 500 (^GSPC)
70.18%

Earnings Trends

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Earnings Per Share

GAAP
Normalized
GAAP
Normalized

Revenue vs. Earnings

Annual
Quarterly
Annual
Quarterly
Q2 FY26
Revenue --
Earnings -43.42M
Profit Margin 0.00%

Q3

FY25

Q4

FY25

Q1

FY26

Q2

FY26

-40M
-30M
-20M
-10M
0
0.0%

Analyst Insights

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Analyst Price Targets

20.00 Low
42.36 Average
34.10 Current
57.00 High

Analyst Recommendations

  • Strong Buy
  • Buy
  • Hold
  • Underperform
  • Sell

Latest Rating

Date 8/27/2026
Analyst Guggenheim
Rating Action Maintains
Rating Buy
Price Action Raises
Price Target 55 -> 57

Statistics

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Valuation Measures

Annual
As of 9/3/2026
  • Market Cap

    3.79B

  • Enterprise Value

    3.55B

  • Trailing P/E

    --

  • Forward P/E

    --

  • PEG Ratio (5yr expected)

    --

  • Price/Sales (ttm)

    --

  • Price/Book (mrq)

    15.85

  • Enterprise Value/Revenue

    --

  • Enterprise Value/EBITDA

    --

Financial Highlights

Profitability and Income Statement

  • Profit Margin

    0.00%

  • Return on Assets (ttm)

    -44.13%

  • Return on Equity (ttm)

    -74.73%

  • Revenue (ttm)

    --

  • Net Income Avi to Common (ttm)

    -152.09M

  • Diluted EPS (ttm)

    -1.41

Balance Sheet and Cash Flow

  • Total Cash (mrq)

    250.76M

  • Total Debt/Equity (mrq)

    2.20%

  • Levered Free Cash Flow (ttm)

    -77.32M

Compare

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Company Insights

Fair Value

34.10 Current

Dividend Score

0 Low
Sector Avg.
100 High

Hiring Score

0 Low
Sector Avg.
100 High

Insider Sentiment Score

0 Low
Sector Avg.
100 High

Research Reports

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  • Daily – Vickers Top Buyers & Sellers for 12/24/2025

    The Vickers Top Buyers & Sellers is a daily report that identifies the five companies the largest insider purchase transactions based on the dollar value of the transactions as well as the five companies the largest insider sales transactions based on the dollar value of the transactions.

  • Daily – Vickers Top Buyers & Sellers for 09/06/2024

    The Vickers Top Buyers & Sellers is a daily report that identifies the five companies the largest insider purchase transactions based on the dollar value of the transactions as well as the five companies the largest insider sales transactions based on the dollar value of the transactions.

  • Daily – Vickers Top Buyers & Sellers for 04/03/2023

    The Vickers Top Buyers & Sellers is a daily report that identifies the five companies the largest insider purchase transactions based on the dollar value of the transactions as well as the five companies the largest insider sales transactions based on the dollar value of the transactions.

  • Daily – Vickers Top Buyers & Sellers for 03/30/2023

    The Vickers Top Buyers & Sellers is a daily report that identifies the five companies the largest insider purchase transactions based on the dollar value of the transactions as well as the five companies the largest insider sales transactions based on the dollar value of the transactions.

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