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Taysha Gene Therapies, Inc. (TSHA)

3.7300 +0.2200 (+6.27%)
At close: 4:00:00 PM EDT
3.8000 +0.0700 (+1.88%)
After hours: 4:36:26 PM EDT
Trade TSHA on Coinbase
Chart Range Bar
Loading chart for TSHA
  • Previous Close 3.5100
  • Open 3.5300
  • Bid 3.7300 x 200
  • Ask 4.4900 x 200
  • Day's Range 3.5000 - 3.7900
  • 52 Week Range 3.4550 - 7.3000
  • Volume 4,529,002
  • Avg. Volume 3,302,989
  • Market Cap (intraday) 1.215B
  • Beta (5Y Monthly) 1.17
  • PE Ratio (TTM) --
  • EPS (TTM) -0.4000
  • Earnings Date Nov 4, 2026
  • Forward Dividend & Yield -- (0.00%)
  • 1y Target Est 13.00
  • Zacks Rating
    Neutral

Taysha Gene Therapies, Inc., a clinical-stage biotechnology company, focuses on developing and commercializing adeno-associated virus-based gene therapies for the treatment of severe monogenic diseases of the central nervous system. The company primarily develops TSHA-120 for the treatment of giant axonal neuropathy; TSHA-102 for the treatment of Rett syndrome; TSHA-121 for the treatment of CLN7 disease; TSHA-118 for the treatment of CLN1 disease; TSHA-105 for the treatment of SLC13A5 deficiency; TSHA-113 for the treatment of tauopathies; TSHA-106 for the treatment of angelman syndrome; and TSHA-114 for the treatment of fragile X syndrome. The company has research, collaboration, and license agreement with The University of Texas Southwestern Medical Center. Taysha Gene Therapies, Inc. was incorporated in 2019 and is headquartered in Dallas, Texas.

www.tayshagtx.com

99

Full Time Employees

December 31

Fiscal Year Ends

Healthcare

Sector

Biotechnology

Industry

Performance Overview

Trailing total returns as of 10/15/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC) .

YTD Return

TSHA
32.18%
S&P 500 (^GSPC)
13.13%

1-Year Return

TSHA
30.15%
S&P 500 (^GSPC)
16.08%

3-Year Return

TSHA
65.04%
S&P 500 (^GSPC)
78.94%

5-Year Return

TSHA
79.14%
S&P 500 (^GSPC)
73.19%

Earnings Trends

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Earnings Per Share

GAAP
Normalized
GAAP
Normalized

Revenue vs. Earnings

Annual
Quarterly
Annual
Quarterly
Q2 FY26
Revenue --
Earnings -46.64M
Profit Margin 0.00%

Q3

FY25

Q4

FY25

Q1

FY26

Q2

FY26

-40M
-30M
-20M
-10M
0
-500.0%
-400.0%
-300.0%
-200.0%
-100.0%
0.0%

Analyst Insights

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Analyst Price Targets

9.00
13.00 Average
3.7300 Current
19.00 High

Analyst Recommendations

  • Strong Buy
  • Buy
  • Hold
  • Underperform
  • Sell

Latest Rating

Date 9/17/2026
Analyst Wolfe Research
Rating Action Initiated
Rating Outperform
Price Action --
Price Target --

Statistics

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Valuation Measures

Annual
As of 9/23/2026
  • Market Cap

    1.60B

  • Enterprise Value

    1.20B

  • Trailing P/E

    --

  • Forward P/E

    --

  • PEG Ratio (5yr expected)

    --

  • Price/Sales (ttm)

    323.85

  • Price/Book (mrq)

    4.13

  • Enterprise Value/Revenue

    218.99

  • Enterprise Value/EBITDA

    --

Financial Highlights

Profitability and Income Statement

  • Profit Margin

    0.00%

  • Return on Assets (ttm)

    -23.82%

  • Return on Equity (ttm)

    -47.06%

  • Revenue (ttm)

    5.49M

  • Net Income Avi to Common (ttm)

    -149.63M

  • Diluted EPS (ttm)

    -0.4000

Balance Sheet and Cash Flow

  • Total Cash (mrq)

    455.41M

  • Total Debt/Equity (mrq)

    14.64%

  • Levered Free Cash Flow (ttm)

    -80.97M

Compare

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Company Insights

Fair Value

3.7300 Current

Dividend Score

0 Low
Sector Avg.
100 High

Hiring Score

0 Low
Sector Avg.
100 High

Insider Sentiment Score

0 Low
Sector Avg.
100 High

Research Reports

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  • Daily – Vickers Top Buyers & Sellers for 07/02/2024

    The Vickers Top Buyers & Sellers is a daily report that identifies the five companies the largest insider purchase transactions based on the dollar value of the transactions as well as the five companies the largest insider sales transactions based on the dollar value of the transactions.

  • Daily – Vickers Top Buyers & Sellers for 08/17/2023

    The Vickers Top Buyers & Sellers is a daily report that identifies the five companies the largest insider purchase transactions based on the dollar value of the transactions as well as the five companies the largest insider sales transactions based on the dollar value of the transactions.

  • Daily – Vickers Top Buyers & Sellers for 02/07/2022

    The Vickers Top Buyers & Sellers is a daily report that identifies the five companies the largest insider purchase transactions based on the dollar value of the transactions as well as the five companies the largest insider sales transactions based on the dollar value of the transactions.

  • Daily – Vickers Top Buyers & Sellers for 02/04/2022

    The Vickers Top Buyers & Sellers is a daily report that identifies the five companies the largest insider purchase transactions based on the dollar value of the transactions as well as the five companies the largest insider sales transactions based on the dollar value of the transactions.

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