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Castle Biosciences, Inc. (CSTL)

34.94 -2.22 (-5.97%)
At close: 4:00:01 PM EST
34.94 0.00 (0.00%)
After hours: 4:00:06 PM EST
Trade CSTL on Coinbase
Chart Range Bar
Loading chart for CSTL
  • Previous Close 37.16
  • Open 37.52
  • Bid 22.02 x 200
  • Ask 40.14 x 200
  • Day's Range 34.46 - 37.52
  • 52 Week Range 17.72 - 44.28
  • Volume 470,254
  • Avg. Volume 377,087
  • Market Cap (intraday) 1.067B
  • Beta (5Y Monthly) 0.95
  • PE Ratio (TTM) --
  • EPS (TTM) -0.64
  • Earnings Date Nov 5, 2026
  • Forward Dividend & Yield -- (0.00%)
  • 1y Target Est 46.70
  • Zacks Rating Neutral

Castle Biosciences, Inc., a molecular diagnostics company, provides test solutions for the diagnosis and treatment of dermatologic cancers, Barrett's esophagus (BE), atopic dermatitis (AD), and uveal melanoma. The company offers DecisionDx-Melanoma, a risk stratification gene expression profile (GEP) test that predicts the likelihood of a positive sentinel lymph node and the risk of metastasis for patients with invasive cutaneous melanoma; TissueCypher, a risk stratification spatialomics test to predict future development of high-grade dysplasia and/or esophageal cancer in patients with non-dysplastic, indefinite dysplasia, and low-grade dysplasia BE; AdvanceAD-Tx, a non-invasive GEP test which is designed to guide systemic treatment selection for patients aged 12 years and older with moderateto-severe AD; DecisionDx-SCC, a GEP test for cutaneous squamous cell carcinoma; and MyPath Melanoma, a diagnostic GEP test for use in patients with difficult-to-diagnose melanocytic lesions. It also provides DecisionDx-UM, a risk stratification GEP test that predicts the risk of metastasis for patients with uveal melanoma. The company offers its products to dermatology and gastroenterology markets. The company was incorporated in 2007 and is headquartered in Friendswood, Texas.

castlebiosciences.com

1,002

Full Time Employees

December 31

Fiscal Year Ends

Healthcare

Sector

Recent News

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Performance Overview

Trailing total returns as of 11/2/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC) .

YTD Return

CSTL
10.18%
S&P 500 (^GSPC)
10.17%

1-Year Return

CSTL
37.02%
S&P 500 (^GSPC)
10.25%

3-Year Return

CSTL
109.85%
S&P 500 (^GSPC)
74.66%

5-Year Return

CSTL
44.35%
S&P 500 (^GSPC)
62.86%

Earnings Trends

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Earnings Per Share

GAAP
Normalized
GAAP
Normalized

Revenue vs. Earnings

Annual
Quarterly
Annual
Quarterly
Q2 FY26
Revenue 103.55M
Earnings -2.06M
Profit Margin -1.99%

Q3

FY25

Q4

FY25

Q1

FY26

Q2

FY26

0
20M
40M
60M
80M
100M
-15.0%
-10.0%
-5.0%

Analyst Insights

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Analyst Price Targets

35.00
46.70 Average
34.94 Current
60.00 High

Analyst Recommendations

  • Strong Buy
  • Buy
  • Hold
  • Underperform
  • Sell

Latest Rating

Date 8/3/2026
Analyst BTIG
Rating Action Maintains
Rating Buy
Price Action Raises
Price Target 40 -> 44

Statistics

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Valuation Measures

Annual
  • Market Cap

  • Enterprise Value

  • Trailing P/E

  • Forward P/E

  • PEG Ratio (current)

  • Price/Sales (ttm)

  • Price/Book (mrq)

  • Enterprise Value/Revenue

  • Enterprise Value/EBITDA

Financial Highlights

Profitability and Income Statement

  • Profit Margin

    -5.43%

  • Return on Assets (ttm)

    -1.36%

  • Return on Equity (ttm)

    -4.20%

  • Revenue (ttm)

    357.28M

  • Net Income Avi to Common (ttm)

    -19.41M

  • Diluted EPS (ttm)

    -0.64

Balance Sheet and Cash Flow

  • Total Cash (mrq)

    266.8M

  • Total Debt/Equity (mrq)

    7.80%

  • Levered Free Cash Flow (ttm)

    -7.26M

Company Insights

Research Reports

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