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Praxis Precision Medicines, Inc. (PRAX)

311.99 -7.29 (-2.28%)
As of 12:34:47 PM EDT. Market Open.
Trade PRAX on Coinbase
Chart Range Bar
Loading chart for PRAX
  • Previous Close 319.28
  • Open 308.97
  • Bid 227.78 x 200
  • Ask 400.75 x 200
  • Day's Range 308.51 - 320.85
  • 52 Week Range 26.70 - 356.00
  • Volume 142,870
  • Avg. Volume 493,804
  • Market Cap (intraday) 8.689B
  • Beta (5Y Monthly) 3.01
  • PE Ratio (TTM) --
  • EPS (TTM) -13.47
  • Earnings Date (est.) Apr 30, 2026
  • Forward Dividend & Yield --
  • Ex-Dividend Date --
  • 1y Target Est 617.62

Praxis Precision Medicines, Inc., a clinical-stage biopharmaceutical company, engages in the development of therapies for central nervous system (CNS) disorders characterized by neuronal excitation-inhibition imbalance in the United States. The company's platforms include Cerebrum, a small molecule platform for CNS small molecule therapies to develop orally available precision therapies; and Solidus to discover and develop antisense oligonucleotide. It also develops ulixacaltamide, a small molecule inhibitor of T-type calcium channels that in NDA for the treatment of essential tremor; relutrigine, a small molecule, which is in NDA for the treatment of SCN2A- and SCN8A-developmental and epileptic encephalopathies (DEE), as well as in Phase 3 trial for broad DEEs; vormatrigine, a small molecule targeting the hyperexcitable state of sodium-channels in the brain that is in Phase 3 trial for the treatment of adjunctive focal epilepsy, as well as in Phase 2 trial for monotherapy focal epilepsy; and Elsunersen, a clinical-stage ASO designed to selectively decrease SCN2A gene expression, which is in Phase 3 trial for the treatment of SCN2A-DEE. In addition, the company is developing product candidates in pre-clinical trial comprising PRAX-020 to treat KCNT1; PRAX-080 that targets PCDH19 mosaic expression disorders; PRAX-090 for targeting SYNGAP1 loss-of-function; and PRAX-100 that targets SCN2A LoF mutations. It has a cooperation and license agreement with RogCon Inc.; and a research collaboration, option, and license agreement with Ionis Pharmaceuticals, Inc. The company was formerly known as EpiPM Therapeutics, Inc. and changed its name to Praxis Precision Medicines, Inc. in October 2016. Praxis Precision Medicines, Inc. was incorporated in 2015 and is headquartered in Boston, Massachusetts.

praxismedicines.com

168

Full Time Employees

December 31

Fiscal Year Ends

Healthcare

Sector

Biotechnology

Industry

Performance Overview: PRAX

Trailing total returns as of 4/2/2026, which may include dividends or other distributions. Benchmark is S&P 500 (^GSPC) .

YTD Return

PRAX
5.85%
S&P 500 (^GSPC)
4.22%

1-Year Return

PRAX
740.72%
S&P 500 (^GSPC)
15.62%

3-Year Return

PRAX
2,470.99%
S&P 500 (^GSPC)
59.56%

5-Year Return

PRAX
32.58%
S&P 500 (^GSPC)
63.11%

Earnings Trends: PRAX

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Earnings Per Share

GAAP
Normalized
GAAP
Normalized

Revenue vs. Earnings

Annual
Quarterly
Annual
Quarterly
Q4 FY25
Revenue --
Earnings -88.91M

Q1

FY25

Q2

FY25

Q3

FY25

Q4

FY25

-80M
-60M
-40M
-20M
0

Analyst Insights: PRAX

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Analyst Price Targets

130.00 Low
617.62 Average
311.99 Current
1,245.00 High

Analyst Recommendations

  • Strong Buy
  • Buy
  • Hold
  • Underperform
  • Sell

Latest Rating

Date 2/24/2026
Analyst Wolfe Research
Rating Action Initiated
Rating Outperform
Price Action Announces
Price Target 500

Statistics: PRAX

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Valuation Measures

Annual
As of 4/1/2026
  • Market Cap

    8.89B

  • Enterprise Value

    8.29B

  • Trailing P/E

    --

  • Forward P/E

    --

  • PEG Ratio (5yr expected)

    --

  • Price/Sales (ttm)

    953.14

  • Price/Book (mrq)

    10.13

  • Enterprise Value/Revenue

    1.22k

  • Enterprise Value/EBITDA

    --

Financial Highlights

Profitability and Income Statement

  • Profit Margin

    0.00%

  • Return on Assets (ttm)

    -28.69%

  • Return on Equity (ttm)

    -45.83%

  • Revenue (ttm)

    --

  • Net Income Avi to Common (ttm)

    -303.27M

  • Diluted EPS (ttm)

    -13.47

Balance Sheet and Cash Flow

  • Total Cash (mrq)

    599.33M

  • Total Debt/Equity (mrq)

    0.01%

  • Levered Free Cash Flow (ttm)

    -146.25M

Compare To: PRAX

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Company Insights: PRAX

Fair Value

311.99 Current

Dividend Score

0 Low
Sector Avg.
100 High

Hiring Score

0 Low
Sector Avg.
100 High

Insider Sentiment Score

0 Low
Sector Avg.
100 High

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